|  |  | all patients |  | patients with breast volume <750 cm³ |  | patients with breast volume ≥750 cm³ | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  | (n = 83) |  | (n = 48) |  | (n = 35) | |||||||||||||||
Gene (codon) | Genotype | aa | n (%) | G0/1a | G2/3a | ORb | 95% CIc | Pd | aa | n (%) | G0/1a | G2/3a | ORb | 95% CIc | Pd | aa | n (%) | G0/1a | G2/3a | ORb | 95% CIc | Pd |
ATM | GG |  | 63 (76) | 28 | 35 | 1 |  |  |  | 36 (75) | 20 | 16 | 1 |  |  |  | 27 (77) | 8 | 19 | 1 | 0.19 – 5.68 |  |
(1853) | GA |  | 18 (22) | 9 | 9 | 1.18 | 0.45 – 3.25 | 0.826 |  | 11 (23) | 6 | 5 | 1.43 | 0.38 – 5.67 | 0.573 |  | 7 (20) | 3 | 4 | 0.92 | 0.04 – 32.21 | 1.000 |
 | AA |  | 2 (2) | 0 | 2 | 1.38 | 0.20 – 10.59 |  |  | 1 (2) | 0 | 1 | 2.05 | 0.15 – 32.15 |  |  | 1 (3) | 0 | 1 | 0.84 |  |  |
GSTP1 | AA | Â | 37 (45) | 19 | 18 | 1 | Â | Â | Â | 21 (44) | 12 | 9 | 1 | Â | Â | Â | 16 (46) | 7 | 9 | 1 | Â | Â |
(105) | AG |  | 38 (45) | 12 | 26 | 1.01 | 0.49 – 2.09 | 1.000 |  | 21 (44) | 10 | 11 | 0.98 | 0.39 – 2.44 | 1.000 |  | 17 (48) | 2 | 15 | 1.25 | 0.32 – 5.29 | 0.772 |
 | GG |  | 8 (10) | 6 | 2 | 1.02 | 0.24 – 4.35 |  |  | 6 (12) | 4 | 2 | 0.96 | 0.15 – 5.97 |  |  | 2 (6) | 2 | 0 | 1.56 | 0.10 – 28.03 |  |
TGFB1 | CC | Â | 29 (35) | 14 | 15 | 1 | Â | Â | Â | 18 (38) | 13 | 5 | 1 | Â | Â | Â | 11 (31) | 1 | 10 | 1 | Â | Â |
(pos-509) | CT |  | 40 (48) | 18 | 22 | 1.26 | 0.65 – 2.50 | 0.530 |  | 24 (50) | 12 | 12 | 3.10 | 1.11 –10.21 | 0.028 |  | 16 (46) | 6 | 10 | 0.36 | 0.10 – 1.14 | 0.083 |
 | TT |  | 14 (17) | 5 | 9 | 1.59 | 0.42 – 6.24 |  |  | 6 (12) | 1 | 5 | 9.58 | 1.23 – 104.30 |  |  | 8 (23) | 4 | 4 | 0.13 | 0.01 – 1.29 |  |
XPD e | GG | Â | 34 (42) | 19 | 15 | 1 | Â | Â | Â | 20 (43) | 12 | 8 | 1 | Â | Â | Â | 14 (40) | 7 | 7 | 1 | Â | Â |
(751) | GT |  | 38 (46) | 14 | 24 | 1.85 | 0.90 – 4.00 | 0.098 |  | 20 (43) | 10 | 10 | 1.42 | 0.59 – 3.59 | 0.420 |  | 18 (51) | 4 | 14 | 3.95 | 0.91 – 22.75 | 0.046 |
 | TT |  | 10 (12) | 3 | 7 | 3.44 | 0.81 – 16.01 |  |  | 7 (14) | 3 | 4 | 2.03 | 0.34 – 12.89 |  |  | 3 (9) | 0 | 3 | 15.62 | 0.84 – 517.40 |  |
XRCC1 | GG | Â | 36 (43) | 17 | 19 | 1 | Â | Â | Â | 25 (52) | 14 | 11 | 1 | Â | Â | Â | 11 (31) | 3 | 8 | 1 | Â | Â |
(399) | GA |  | 33 (40) | 13 | 20 | 1.02 | 0.54 – 1.93 | 1.000 |  | 17 (35) | 9 | 8 | 1.13 | 0.46 – 2.76 | 0.840 |  | 16 (46) | 4 | 12 | 0.62 | 0.20 – 1.84 | 0.464 |
 | AA |  | 14 (17) | 7 | 7 | 1.04 | 0.29 – 3.73 |  |  | 6 (12) | 3 | 3 | 1.27 | 0.21 – 7.63 |  |  | 8 (23) | 4 | 4 | 0.39 | 0.04 – 3.39 |  |