| | | Paired comparison |
---|
Sample | %Tail DNA | SD | Compared pair | F-value | p-value |
---|
0 Gy | 6.2 | 7.6 | | | |
0 + 2 Gy | 9.7 | 6.5 | 0 Gy / 0 + 2 Gy | 24.03 | <0.001 |
2 Gy | 15.5 | 6.9 | 0 + 2 Gy / 2 Gy | 74.31 | <0.001 |
2 + 4 Gy | 16.9 | 8.9 | 2 Gy / 2 + 4 Gy | 3.220 | 0.073 |
4 Gy | 20.7 | 8.1 | 2 + 4 Gy / 4 Gy | 20.36 | <0.001 |
4 + 8 Gy | 30.1 | 12.3 | 4 Gy / 4 + 8 Gy | 80.78 | <0.001 |
8 Gy | 43.1 | 14.4 | 4 + 8 Gy / 8 Gy | 94.78 | <0.001 |
- Leukocytes (200 leukocytes/sample of one donor) were irradiated with increasing doses (0-8 Gy) and mixed in equal proportions with the next higher irradiation dose level sample. Comparison of mean DNA damage in %Tail DNA for samples treated with 0, 2, 4 or 8 Gy and mixtures (0 and 2 Gy, 2 and 4 Gy, 4 and 8 Gy) revealed significant differences for almost all pairs and a trend for cells irradiated with 2 Gy vs. 2 + 4 Gy.
- Abbreviations: SD = standard deviation, p-value = probability value, F-value.