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Table 2 Significant factors in multivariate analysis

From: Local prostate cancer radiotherapy after prostate-specific antigen progression during primary hormonal therapy

 

Hazard ratio

95% confidence interval

P-value

Biochemical recurrence free survival

   

T stage ≤2a

1.7

1.1-2.5

0.014

PSA <10ng/ml

1.9

1.2-2.8

0.003

no PSA progression vs. PSA pr. with HT

3.4

1.9-6.0

<0.001

no PSA progression vs. no HT

1.5

1.2-21

0.024

nadir ≤0.5 vs. >0.5 after initial HT

4.7

1.1-19

0.034

Disease specific survival

   

Gleason score ≤6

4.0

1.8-9.1

0.001

no HT vs. PSA progression with HT

23

7.3-72

<0.001

no PSA progression vs. PSA pr. with HT

9.1

3.7-22

<0.001

Overall survival

   

age <70years

2.6

1.5-4.4

<0.001

Gleason score ≤6

2.2

1.4-3.7

0.002

no HT vs. PSA progression with HT

5.2

3.6-9.4

<0.001

no PSA progression vs. PSA pr. with HT

7.2

3.9-14

<0.001

  1. Abbreviations: PSA = prostate-specific antigen; HT = hormonal therapy.