Skip to main content

Table 5 Odds Ratios for Choice of WBRT with SRS versus SRS alone

From: Physician self-reported treatment of brain metastases according to patients’ clinical and demographic factors and physician practice setting

WBRT+SRS vs SRS

OR (95%CI)

P

Lesions

  

1 (referent)

1.00

 

3

2.1 (1.7,2.6)

<.0001

8

6.7 (2.4,18.5)

0.0002

Age

  

55 (referent)

1.00

 

80

0.6 (0.5,0.7)

<.0001

Extracranial Disease

  

None (referent)

1.00

 

Active

0.9 (0.7,1.3)

0.6576

Focal Neurological Deficits

  

Asymptomatic (referent)

1.00

 

Symptomatic

1.4 (1.1,1.7)

0.0021

Performance Status§

  

80 (referent)

1.00

 

50

0.7 (0.5,0.9)

0.0101

Lesion Size

  

Small (referent)

1.00

 

Large

5.6 (3.2,9.8)

<.0001

Melanoma

  

NSCLC¶ (referent)

1.00

 

Melanoma

0.5 (0.4,0.6)

<.0001

  1. Notes
  2. Odds ratios (OR) are quoted with their 95% confidence intervals in parentheses. "*" Denotes significant odds ratios at the 0.05 level.
  3. The odds ratios compare odds of choosing each given treatment, with the odds of choosing the treatments serving as reference categories.
  4. * Whole brain radiation therapy.
  5. † Stereotactic radiosurgery.
  6. †† Confidence intervals.
  7. § Karnofsky Performance Status.
  8. ¶ Non-Small Cell Lung Cancer.