Figure 4

Effect of combination treatment on tumour growth delay. A Modified growth delay to four-fold of starting volume after combined treatment. Given are Kaplan-Meier-plots of mock-irradiated tumours combined with vehicle (open black diamonds) or 40 mg/kg BW Erufosine (open red squares) and 5 × 3.3 Gy combined with vehicle (closed black diamonds) or 40 mg/kg BW Erufosine (closed red squares). B Respective computed median growth delay of data obtained in A) with 95%-confidence interval (n=14-18). C Modified growth delay to eight-fold of starting volume after combined treatment. Given are Kaplan-Meier-plots of mock- irradiated tumours combined with vehicle (open black diamonds) or 40 mg/kg BW Erufosine (open red squares) and 5 × 3.3 Gy combined with vehicle (closed black diamonds) or 40 mg/kg BW Erufosine (closed red squares). D Respective computed median growth delay of data obtained in C) with 95%-confidence interval (n=14-18).