Table 1 Clonogenic Assay: Surviving Fraction (SF) of irradiated cells (n = 3 for each experiment); n.d. = not determined
plating after irradiation | plating before irradiation | |||||||
|---|---|---|---|---|---|---|---|---|
A 549 | 250 cells | 500 cells | mean value | S.D. | 50 cells | 100 cells | mean value | S.D. |
0 Gy | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | ||
1 Gy | 67.9% | 66.3% | 67.1% | 1.1% | 97.7% | 87.2% | 92.5% | 7.4% |
2 Gy | 62.3% | 60.8% | 61.6% | 1.0% | 90.7% | 75.8% | 83.3% | 10.5% |
4 Gy | 22.6% | 24.7% | 23.7% | 1.5% | 55.8% | 34.6% | 45.2% | 15.0% |
6 Gy | n.d. | 25.6% | 19.0% | 22.3% | 4.7% | |||
8 Gy | 5.0% | 4.1% | 4.6% | 0.6% | 16.3% | 10.4% | 13.4% | 4.1% |
15 Gy | 3.4% | 0.0% | 1.7% | 2.4% | 2.3% | 1.9% | 2.1% | 0.3% |
LN 229 | 250 cells | 500 cells | Mean value | S.D. | 100 cells | 200 cells | Mean value | S.D. |
0 Gy | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | ||
1 Gy | 90.5% | 90.2% | 88.9% | 3.1% | 109.0% | 89.5% | 99.5% | 16.7% |
2 Gy | 77.0% | 60.3% | 67.7% | 2.2% | 38.8% | 45.0% | 41.9% | 12.7% |
4 Gy | 20.3% | 21.1% | 20.6% | 0.7% | 12.9% | 14.1% | 13.5% | 2.4% |
6 Gy | n.d. | 1.6% | 3.7% | 2.6% | 1.7% | |||
8 Gy | 1.7% | 1.7% | 1.7% | 0.1% | 0.0% | 0.0% | 0.0% | 0.0% |
15 Gy | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
F 98 | 75 cells | 100 cells | Mean value | S.D. | ||||
0 Gy | n.d. | 100.0% | 100.0% | 100.0% | ||||
1 Gy | 74.1% | 57.4% | 65.8% | 15.4% | ||||
4 Gy | 33.3% | 41.0% | 37.2% | 7.7% | ||||
6 Gy | 33.3% | 28.7% | 31.0% | 8.8% | ||||