| Surgery Only (n = 34) | Surgery+CT (n = 40) | Surgery+CRT (n = 40) | CRT+Surgery+CT (n = 40) | P Value | ||||
---|---|---|---|---|---|---|---|---|---|
 | Mean | Median (range) | Mean | Median (range) | Mean | Median (range) | Mean | Median (range) |  |
Globe health status | 67 | 75 (25-83) | 64 | 75 (25-83) | 69 | 75 (25-92) | 62 | 75 (25-92) | 0.464 |
Functional Scales/Items | |||||||||
EORTC QLQ-C30 | |||||||||
   Physical functioning | 64 | 67 (20-93) | 67 | 73 (13-93) | 69 | 73 (13-93) | 70 | 73 (40-93) | 0.529 |
   Role functioning | 59 | 67 (17-100) | 59 | 67 (17-100) | 55 | 50 (0-100) | 60 | 67 (0-100) | 0.496 |
   Emotional functioning | 55 | 58 (17-100) | 54 | 58 (25-100) | 56 | 58 (25-100) | 58 | 58 (17-100) | 0.774 |
   Cognitive functioning | 68 | 83 (33-100) | 69 | 83 (17-100) | 71 | 83 (33-100) | 72 | 83 (33-100) | 0.814 |
   Social functioning | 72 | 83 (0-100) | 66 | 75 (0-100) | 73 | 83 (17-100) | 71 | 83 (0-100) | 0.563 |
EORTC QLQ-CR29 | |||||||||
   AAnxiety | 84 | 83 (50-100) | 87 | 83 (50-100) | 86 | 83 (50-100) | 88 | 83 (50-100) | 0.145 |
   Body image | 96 | 100 (67-100) | 98 | 100 (67-100) | 95 | 100 (44-100) | 99 | 100 (78-100) | 0.685 |
   Male Sexual function | 61 | 67 (33-100) | 60 | 67 (0-100) | 57 | 67 (0-100) | 64 | 67 (0-100) | 0.968 |
   Female Sexual function | 48 | 50 (0-100) | 48 | 33 (0-100) | 53 | 33 (33-100) | 42 | 33(0-100) | 0.529 |
Symptom Scales/Items | |||||||||
EORTC QLQ-C30 | |||||||||
   Fatigue | 38 | 33 (22-67) | 43 | 44 (22-100) | 39 | 33 (0-89) | 35 | 33 (0-78) | 0.409 |
   Nausea and vomiting | 5 | 0 (0-33) | 3 | 0 (0-33) | 6 | 0 (0-33) | 3 | 0 (0-17) | 0.208 |
   Pain | 18 | 17 (0-67) | 21 | 17 (0-67) | 20 | 17 (0-50) | 16 | 17 (0-50) | 0.627 |
   Dyspareunia | 5 | 0 (0-67) | 12 | 0 (0-67) | 10 | 0 (0-33) | 5 | 0 (0-33) | 0.124 |
   Insomnia | 30 | 33 (0-100) | 21 | 0 (0-100) | 22 | 17 (0-100) | 31 | 33 (0-100) | 0.158 |
   Appetite loss | 10 | 0 (0-67) | 18 | 0 (0-67) | 14 | 0 (0-67) | 12 | 0 (0-67) | 0.375 |
   Constipation | 24 | 33 (0-100) | 23 | 33 (0-67) | 20 | 33 (0-67) | 21 | 33 (0-67) | 0.923 |
   Diarrhoea | 26 | 33 (0-67) | 32 | 33 (0-67) | 45 | 33 (0-100) | 48 | 33 (0-100) | 0.001 |
   Financial difficulties | 60 | 67 (0-100) | 59 | 67 (0-100) | 68 | 67 (0-100) | 63 | 67 (0-100) | 0.509 |
EORTC QLQ-CR29 | |||||||||
   Micturition problems | 8 | 0 (0-67) | 9 | 0 (0-56) | 6 | 0 (0-33) | 6 | 0 (0-33) | 0.844 |
   Abdominal and pelvic pain scale | 7 | 0 (0-22) | 7 | 0 (0-33) | 8 | 0 (0-33) | 5 | 0 (0-44) | 0.396 |
   Defaecation problems | 10 | 8 (0-33) | 9 | 8 (0-42) | 10 | 8 (0-25) | 9 | 0 (0-75) | 0.321 |
   Faecal incontinence scale | 19 | 17 (0-27) | 23 | 17 (0-67) | 28 | 33 (0-50) | 30 | 33 (0-67) | 0.006 |
   Bloated feeling | 5 | 0 (0-67) | 9 | 0 (0-67) | 14 | 0 (0-67) | 3 | 0 (0-33) | 0.003 |
   Dry mouth | 6 | 0 (0-33) | 7 | 0 (0-33) | 5 | 0 (0-33) | 17 | 0 (0-67) | 0.071 |
   Hair loss | 2 | 0 (0-33) | 9 | 0 (0-100) | 7 | 0 (0-67) | 7 | 0 (0-100) | 0.422 |
   Trouble with taste | 4 | 0 (0-67) | 3 | 0 (0-67) | 7 | 0 (0-33) | 2 | 0 (0-33) | 0.072 |
   Sore skin | 7 | 0 (0-67) | 8 | 0 (0-33) | 10 | 0 (0-67) | 9 | 0 (0-67) | 0.815 |
   Embarrassed by Bowel Movement | 9 | 0 (0-67) | 8 | 0 (0-33) | 10 | 0 (0-33) | 6 | 0 (0-33) | 0.572 |
   Stoma related problems | 5 | 0 (0-33) | 7 | 0 (0-33) | 16 | 0 (0-33) | 11 | 0 (0-67) | 0.161 |
   Impotence | 13 | 0 (0-67) | 15 | 0 (0-67) | 19 | 0 (0-100) | 32 | 33 (0-100) | 0.215 |
   Dyspareunia* | 0 | 0 (0-0) | 5 | 0 (0-33) | 21 | 0 (0-100) | 0 | 0 (0-0) | 0.004 |