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Table 1 Relative reduction in surviving fraction of three glioma cells due to combination of irradiation and BO-1051 treatment

From: Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response

Irradiation dose (Gy)

Relative reduction (%)

 

U87MG

U251MG

GBM-3

2

41.7

42.6

40.6

4

70.4

45.6

47.0

6

74.2

47.9

64.3

8

76.3

50.0

73.9

  1. Percentage relative reduction of the observed surviving fraction (SF) compared to the expected SF (calculated on the basis of combing individual treatment component, each with respective SF value).