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Table 1 Calculated model parameter values and 95% confidence intervals (in parentheses).

From: A comparison of dose-response characteristics of four NTCP models using outcomes of radiation-induced optic neuropathy and retinopathy

Data set

Parameter

Logistic

Log-logistic

Poisson

Probit

RION, twice daily*

D50, Gy

96.3 (69.8,∞)

125.2 (71.8, ∞)

119.0 (75.6, ∞)

104.4 (71.7, ∞)

 

γ

1.56 (0.49,3.18)

0.80 (-0.09,2.38)

0.93(0.42,1.65)

1.27(0.47,2.42)

RION, once daily

D50, Gy

94.2 (80.5,146.8)

104.7 (82.8,254.2)

102.0 (83.9,161.9)

96.7 (81.5,150.0)

 

γ

1.41 (0.84,2.16)

0.88 (0.34,1.60)

0.99 (0.66,1.41)

1.25 (0.78,1.85)

RIRP, twice daily

D50, Gy

72.2 (63.9,115.7)

74.2 (63.8,188.7)

75.0 (63.6,133.5)

73.0 (63.8,120.9)

 

γ

2.16 (0.98,3.97)

1.66 (0.42,3.47)

1.51 (0.72,2.73)

1.91 (0.89,3.43)

RIRP, once daily

D50, Gy

72.2 (64.0,91.0)

74.0 (63.1,108.1)

73.0 (62.9,94.4)

72.4 (63.9,91.6)

 

γ

1.20 (0.73,1.80)

0.84 (0.42,1.40)

0.96 (0.64,1.34)

1.12 (0.71,1.62)

  1. *Abbreviations: RION - radiation-induced optic neuropathy; RIRP - radiation-induced retinopathy.