Table 3 Summary of Published Single Institution Experiences
Study | Year | Institution | Period | No. of patients (f/u in months) | Treatment Received | Findings |
|---|---|---|---|---|---|---|
Gruber et al.[9] | 2002 | Universities of Berne and Zurich | 1980-2001 | 28 (68) | Group 1: S (radical) + RT Group 2: S(partial) + RT | 10 year DFS: Group 1: 55% Group 2: 0% |
Lund et al.[10] | 2003 | University College London | 1978-2001 | 45 (57) | Group 1: S alone Group 2: S + RT | Local Recurrence Group 1: 28% Group 2: 8% |
Studies Including Chemotherapy | ||||||
Rastogi et al.[11] | 2006 | King George Medical University | 1988-2004 | 8 (36) | All Patients: S (NCFR) + RT + C | 3 year DFS/OS: 72.9%/71.4% |
Kim et al.[12] | 2007 | Four General Hospitals in South Korea | 1990-2004 | 10 (44.9) | Group 1: S (+/- RT) Group 2: CCRT | 5 year DFS: Group 1: 68% Group 2: 42% |
McLean et al.[13] | 2007 | Emory University-affiliated hospitals | 1991-2006 | 21 (47) | Group 1: S Group 2: S + RT Group 3: S +RT+C | Local Recurrence: Group 1: 0% Group 2: 53.3% Group 3: 43% |
Porter et al.[14] | 2008 | Mayo Clinic Rochester | 1976-2003 | 12 (N/A) | Group 1: S (+/- RT) Group 2: S + C (+/- RT) | Median OS: Group 1: 78 months Group 2: 83+ months |
Bachar et al.[15] | 2008 | Princess Margaret Hospital | 1972-2006 | 39 (82.3) | Group 1: S Group 2: C Group 3: RT Group 4: S + RT | 10 year OS: 69.2% (all groups; OS per group N/A) • S +RT optimal • C did not influence outcome |