Figure 4

Contribution of GP96-expression on locoregional control (LRC) in nodal ECS (A) or pN2 (B) stage-stratified patients, and provides additional information when stratified by risk of ECS (C) or N stage (D). All the survival curves were calculated by the Kaplan-Meier method. ECS(+): positive for nodal ECS; ECS(-): negative for nodal ECS; N0-1: N0-1 stage; N2: N2 stage; GP96(+): GP96 overexpression, as the protein level is 1.5-fold higher in the tumor tissue compared to the normal counterpart; GP96(-): GP96 non-overexpression, as the protein level is comparable or lower (≤ 1.5-fold) 1.5-fold) compared to the normal counterpart.