Figure 6
The effect of anti-DPK3-scFv on apoptosis induction of the xenografted cancer cells in nude mice by irradiation. (A) Immunohistochemistry staining of cleaved caspase-3 in the xenografted tumour tissue sections either non-irradiated or 3 days after the radiotherapy. (B) Expression level of cleaved Caspase-3 in xenografted tumour tissue sections. (C) TUNEL staining of the xenografted tumour sections either non-irradiated or 3 days after the radiotherapy. (D) Apoptosis induction measured from the TUNEL staining of xenografted tumour tissue sections. Expression levels of the detected proteins were expressed as the percentage of positive staining cells. 100 cells were scored for each staining. * P < 0.05 as compared with the tissues of HeLa -pcDNA xenografted tumours.