The effect of external beam radiotherapy volume on locoregional control in patients with locoregionally advanced or recurrent nonanaplastic thyroid cancer

Table 2 Comparison of patient characteristics between the limited field and elective field groups

Patient Characteristics		Limited field	Elective field	p-value
		(n = 11)	(n = 12)
Gender	Female	9	10	1.000*
	Male	2	2
Age (years)	< 45	0	2	0.582*
	45 - 64	5	5
	≥ 65	6	5
KPS	90	4	6	0.680*
	80	7	6
Histologic type	Papillary	11	8	0.093*
	Poorly differentiated	0	4
Recurrence	Primary tumor	3	5	0.667*
	Recurrent tumor	8	7
T stage at diagnosis	T1-2	1	0	0.822*
	T3	6	8
	T4	4	4
N stage at diagnosis	N0	3	1	0.179*
	N1a	6	4
	N1b	2	7
AJCC Stage at diagnosis	I-III	7	6	0.680*
	IVA	4	6
T stage at pre-EBRT	T0-2	2	2	1.000*
	T3	1	2
	T4	8	8
N stage at pre-EBRT	N0	2	1	0.359*
	N1a	3	1
	N1b	6	10
AJCC Stage at pre-EBRT	I-III	1	2	0.640*
	IVA-B	7	8
	IVC	3	2
Tg level (ng/mL)	Median (range)	13.5 (2.7-449)	10.7 (0.2-1411)	0.257^†
	Mean ± SD	76.8 ± 137.7	232.3 ± 431.7
	< 10	5	6	1.000*
	≥ 10	6	6
Thyroid surgery	Subtotal thyroidectomy	2	2	1.000*
	Total thyroidectomy	9	10
Lymph node surgery	CND	3	3	1.000*
	CND+Unilateral SND/MRND	7	7
	CND+Bilateral SND/MRND	1	2
Postoperative residuum	R0-1	2	3	1.000*
	R2	9	9
Radioiodine treatment	No	1	3	0.590*
	Yes	10	9
EBRT dose (EQD₂, Gy)	Median (range)	62.5 (62.5-67.7)	62.5 (60-69)	0.110^†
	Mean ± standard deviation	63.3 ± 1.8	65.1 ± 3.1
EBRT techniques	3DCRT	3	3	1.000*
	IMRT	8	9

Abbreviation: 3DCRT = 3-dimensional conformal radiotherapy; IMRT = intensity modulated radiotherapy; same as in Table 1.
*Fisher's exact test.
^†t-test.

ISSN: 1748-717X