Table 1 Summary of results on published studies on the conventional radiotherapy of skull base meningiomas
From: Radiotherapy and radiosurgery for benign skull base meningiomas
authors | Patients (n) | S + RT (%) | RT (%) | Volume (ml) | Dose (Gy) | Follow-up (months) | Local control (%) | Late toxicity (%) |
|---|---|---|---|---|---|---|---|---|
Carella et al.,1982 | 57 | 84 | 16 | NA | 55 - 60 | NA | 95 | NA |
Forbes et al., 1984 | 31 | 100 | 0 | NA | 53 | 45 | 72 at 4 years | 13 |
Barbaro et al., 1987 | 54 | 100 | 0 | NA | 52.5 | 78 | 68 | 0 |
Miralbell et al., 1992 | 36 | 100 | 0 | NA | 45-64 | 88 | 84 at 8 years | 16 |
Goldsmith et al., 1994 | 117 | 100 | 0 | NA | 54 | 40 | 89 at 5 and 77 at 10 years | 3.6 |
Maire et al., 1995 | 91 | 52 | 48 | NA | 52 | 40 | 94 | 6.5 |
Peele et al., 1996 | 42 | 100 | 0 | NA | 55 | 48 | 100 | 5 |
Condra et al.,1997 | 28 | 75 | 25 | NA | 53.3 | 98 | 87 at 15 years | 24 |
Connell et al., 1999 | 54 | 80 | 20 | NA | 54 | 55 | 76 at 5 years | 19 |
Maguire et al., 1999 | 26 | 78 | 22 | NA | 53 | 41 | 8 at 8 years | 8 |
Nutting et al., 1999 | 82 | 100 | 0 | NA | 55-60 | 41 | 92 at 5 and 83 at 10 years | 14 |
Vendrely et al., 1999 | 156 | 51 | 49 | NA | 50 | 40 | 79 at 5 years | 11.5 |
Dufour et al., 2001 | 31 | 55 | 45 | NA | 52 | 73 | 93 at 5 and 10 years | 3.2 |
Pourel et al., 2001 | 28 | 80 | 20 | NA | 56 | 30 | 95 at 5 years | 4 |
Mendenhall et al., 2003 | 101 | 35 | 65 | NA | 54 | 64 | 95 at 5, 92 at 10 and 15 years | 8 |