Figure 1
From: SCLC extensive disease – treatment guidance by extent or/and biology of response?
Suggested treatment strategy for ED-SCLC. Based on recent and older, hardly considered data [2, 5] there could be three different treatment strategies according to initial response to chemotherapy: Chemotherapy plus TRT (simultaneously with the 4th cycle) and PCI for good responders achieving complete remission at least at distant levels; chemotherapy and PCI for patients having any response; second line chemotherapy or best supportive care for stable or progressive disease.