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Table 2 Prognostic groups stratification and radiation doses prescriptions:

From: Intensity modulated radiotherapy for localized prostate cancer: rigid compliance to dose-volume constraints as a warranty of acceptable toxicity?

 

Prognostic groups§

 

Low Risk

Intermediate Risk

High Risk

Highest serum PSA level (ng/ml)

≤ 10

AND

> 10 e < 20

OR

≥ 20

OR

Stage (AJCC 1997)

≤ T2aN0M0

AND

T2bN0M0

OR

≥ T3N0M0

OR

Gleason Score

≤ 6 (3 + 3)

7

≥ 7

OR 2 Intermediate Risk factors associated

Patients number*

38 (30.4%)

28 (22.4%)

57 (45.6%)

Neo-adjuvant hormonal therapy

12/38

14/28

31/57

Post-operative therapy

6/38

4/28

25/57

  1. § Suggested radiation dose prescription: 72 Gy to post-operative radiotherapy, 74 Gy to low risk, 76 Gy to intermediate risk and 78 Gy to high risk patients, respectively PTV: planning target volume
  2. * 2 patients could not have their risks assessed