Figure 7
From: Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition
Histone acetylation by SAHA and MS-275. The HCT116 cells were treated with SAHA (upper panel) or MS-275 (lower panel) in increasing concentrations, and protein extracts prepared after 12 and 24 hours of incubation were analyzed by Western blot immunostaining with antibodies against acetylated histones H3 (acetyl-H3) and H4 (acetyl-H4). α-tubulin was measured as protein loading control.