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  1. Accurate target localization is mandatory in the accelerated partial breast irradiation (APBI) delivery. Dosimetric verification for positional error will further guarantee the accuracy of treatment delivery. ...

    Authors: Jiazhou Wang, Weigang Hu, Gang Cai, Jiayuan Peng, Ziqiang Pan, Xiaomao Guo and Jiayi Chen
    Citation: Radiation Oncology 2013 8:214
  2. The co-incidence of synchronous intraepithelial neoplasia and early stage invasive lung cancer is not a rare phenomenon. The need for curative treatment and the invasive potential of squamous cell pulmonary ca...

    Authors: Feras Oskan, Christine Kornhuber, Grit Krause and Dirk Vordermark
    Citation: Radiation Oncology 2013 8:213
  3. We estimated sufficient setup margins for head-and-neck cancer (HNC) radiotherapy (RT) when 2D kV images are utilized for routine patient setup verification. As another goal we estimated a threshold for the di...

    Authors: Mika Kapanen, Marko Laaksomaa, Tapio Tulijoki, Seppo Peltola, Tuija Wigren, Simo Hyödynmaa and Pirkko-Liisa Kellokumpu-Lehtinen
    Citation: Radiation Oncology 2013 8:212
  4. To investigate for prostate cancer patients the comparison of ‘in-vivo’ measured portal dose images (PDIs) with predictions based on a kilovoltage cone-beam CT scan (CBCT), acquired during the same treatment f...

    Authors: Ali SAM Ali, Maarten LP Dirkx, Ruud M Cools and Ben JM Heijmen
    Citation: Radiation Oncology 2013 8:211
  5. To report our initial clinical experience of helical tomotherapy (HT) in the treatment of locally advanced oropharynx and inoperable oral cavity cancer.

    Authors: Vittorio Donato, Michele Cianciulli, Sofia Fouraki, Leonardo Vigna, Alberto Rocco, Nicola Raffetto and Gianluca Bellocchi
    Citation: Radiation Oncology 2013 8:210
  6. Chloroquine (CLQ), an antimalarial drug, has a lysosomotropic effect associated with increased radiationsensibility, which is mediated by the leakage of hydrolytic enzymes, increased apoptosis, autophagy and i...

    Authors: Luis L Rojas-Puentes, Marcelino Gonzalez-Pinedo, Alejando Crismatt, Alette Ortega-Gomez, Carlos Gamboa-Vignolle, Rodrigo Nuñez-Gomez, Yusmiren Dorantes-Gallareta, Claudia Arce-Salinas and Oscar Arrieta
    Citation: Radiation Oncology 2013 8:209
  7. To retrospectively analyze whether primary tumor volume and primary nodal volume could be considered independent prognostic factors for nasopharyngeal carcinoma treated with intensity-modulated radiation therapy.

    Authors: Mei Feng, Weidong Wang, Zixuan Fan, Binyu Fu, Jie Li, Shichuan Zhang and Jinyi Lang
    Citation: Radiation Oncology 2013 8:208
  8. The goal of this study was to assess a possible dosimetric advantage of intensity modulated radiotherapy (IMRT) of upper abdominal malignancies compared to three-dimensional conformal radiotherapy (3DCRT), and...

    Authors: Alaa Ahmad Nour, Aziz Alaradi, Adel Mohamed, Saleh Altuwaijri and Volker Rudat
    Citation: Radiation Oncology 2013 8:207
  9. The α/β ratio for prostate cancer is postulated being in the range of 0.8 to 2.2 Gy, giving rise to the hypothesis that there may be a therapeutic advantage to hypofractionation. To do so, we carried out a random...

    Authors: Darius Norkus, Agata Karklelyte, Benedikt Engels, Harijati Versmessen, Romas Griskevicius, Mark De Ridder, Guy Storme, Eduardas Aleknavicius, Ernestas Janulionis and Konstantinas Povilas Valuckas
    Citation: Radiation Oncology 2013 8:206
  10. Stereotactic irradiation of large or critically located arteriovenous malformations (AVMs) is a special challenge for clinicians and radiation physicists. To date, no comprehensive comparison of two linac-base...

    Authors: SÅ‚awomir Blamek, Aleksandra GrzÄ…dziel and Leszek Miszczyk
    Citation: Radiation Oncology 2013 8:205
  11. Survival of patients with brain metastasis particularly from historically more radio-resistant malignancies remains dismal. A phase I study of concurrent bortezomib and whole brain radiotherapy was conducted t...

    Authors: Christopher D Lao, Judah Friedman, Christina I Tsien, Daniel P Normolle, Christopher Chapman, Yue Cao, Oliver Lee, Matt Schipper, Catherine Van Poznak, Daniel Hamstra, Theodore Lawrence, James Hayman and Bruce G Redman
    Citation: Radiation Oncology 2013 8:204
  12. Neoadjuvant chemoradiation therapy followed by curative surgery has gained acceptance as the therapy of choice in locally advanced rectal cancer. However, deterioration of anorectal function after long-course ...

    Authors: Bong-Hyeon Kye, Hyung-Jin Kim, Jun-Gi Kim, Sung-Hwan Kim, Byoung-Yong Shim, Nan-Sook Lee and Hyeon-Min Cho
    Citation: Radiation Oncology 2013 8:203
  13. The effect of insufficient node sampling in patients with rectal cancer managed by neoadjuvant chemoradiation followed by surgery has not been clearly determined. We evalulated the impact of insufficient sampl...

    Authors: Won-Suk Lee, Seok Ho Lee, Jeong-Heum Baek, Woon Kee Lee, Jung Nam Lee, Na Rae Kim and Yeon Ho Park
    Citation: Radiation Oncology 2013 8:202
  14. Accelerated hypofractionated radiotherapy can shorten total treatment time and overcome the accelerated repopulation of tumour cells during radiotherapy. This therapeutic approach has demonstrated good efficac...

    Authors: Qiang Lin, Yue-E Liu, Xiao-Cang Ren, Na Wang, Xue-Ji Chen, Dong-Ying Wang, Jie Zong, Yu Peng, Zhi-Jun Guo and Jing Hu
    Citation: Radiation Oncology 2013 8:201
  15. The objective of this retrospective analysis is to systematically assess osseous lesions on the basis of a validated scoring system in terms of stability and fractures prior to and following radiotherapy in 33...

    Authors: Harald Rief, Marc Bischof, Thomas Bruckner, Thomas Welzel, Vasileios Askoxylakis, Stefan Rieken, Katja Lindel, Stephanie Combs and Jürgen Debus
    Citation: Radiation Oncology 2013 8:200
  16. The role of adjuvant radiotherapy (RT) for patients with stage III thymoma after complete resection is not definite. Some authors have advocated postoperative RT after complete tumor resection, but some others...

    Authors: Chengcheng Fan, Qinfu Feng, Yidong Chen, Yirui Zhai, Zongmei Zhou, Dongfu Chen, Zefen Xiao, Hongxing Zhang, Jian Li, Zhouguang Hui, Jun Liang, Jima Lv, Yousheng Mao, Luhua Wang and Jie He
    Citation: Radiation Oncology 2013 8:199
  17. Increasing the radiotherapy dose can result in improved local control for non-small-cell lung cancer (NSCLC) and can thereby improve survival. Accelerated hypofractionated radiotherapy can expose tumors to a h...

    Authors: Yue-E Liu, Qiang Lin, Fan-Jie Meng, Xue-Ji Chen, Xiao-Cang Ren, Bin Cao, Na Wang, Jie Zong, Yu Peng, Ya-Jun Ku and Yan Chen
    Citation: Radiation Oncology 2013 8:198
  18. Treating prostate cancer with SBRT could potentially minimize radiation proctitis by reducing high-dose rectal irradiation. In addition, it offers the potential radiobiologic benefits of hypofractionation. Thi...

    Authors: Sumit Sood, Andrew W Ju, Honkung Wang, Siyuan Lei, Sunghae Uhm, Guowei Zhang, Simeng Suy, John Carroll, John Lynch, Anatoly Dritschilo and Sean P Collins
    Citation: Radiation Oncology 2013 8:197
  19. To determine the biological effectiveness of single, fractionated and continuous low dose rate irradiation on the human colorectal cancer cell line CL187 in vitro and explore the cellular mechanisms.

    Authors: Hao Wang, Jinna Li, Ang Qu, Jingjia Liu, Yong Zhao and Junjie Wang
    Citation: Radiation Oncology 2013 8:196
  20. Glioma stem cells in the quiescent state are resistant to clinical radiation therapy. An almost inevitable glioma recurrence is due to the persistence of these cells. The high linear energy transfer associated...

    Authors: Ting Sun, Zizhu Zhang, Bin Li, Guilin Chen, Xueshun Xie, Yongxin Wei, Jie Wu, Youxin Zhou and Ziwei Du
    Citation: Radiation Oncology 2013 8:195
  21. We describe five patients receiving a re-implantation (RI) after post-operative dosimetry of the primary 125-I permanent prostate brachytherapy (BT) for prostate cancer revealed an insufficient dose coverage.

    Authors: Paul Martin Putora, Ludwig Plasswilm, Wolf Seelentag, Johann Schiefer, Patrick Markart, Hans-Peter Schmid and Daniel Engeler
    Citation: Radiation Oncology 2013 8:194
  22. The modulated arc (mARC) technique has recently been introduced by Siemens as an analogue to VMAT treatment. However, up to now only one certified treatment planning system supports mARC planning. We therefore...

    Authors: Yvonne Dzierma, Frank Nuesken, Norbert Licht and Christian Ruebe
    Citation: Radiation Oncology 2013 8:193
  23. Radiologic response of brain tumors is traditionally assessed according to the Macdonald criteria 10 weeks from the start of therapy. Because glioblastoma (GB) responds in days rather than weeks after boron ne...

    Authors: Ryo Hiramatsu, Shinji Kawabata, Motomasa Furuse, Shin-Ichi Miyatake and Toshihiko Kuroiwa
    Citation: Radiation Oncology 2013 8:192
  24. The Montpellier cancer institute phase II trial started in 2004 and evaluated the feasibility of intraoperative radiotherapy (IORT) technique given as a sole radiation treatment for patients with an excellent ...

    Authors: Claire Lemanski, David Azria, Sophie Gourgou-Bourgade, Norbert Ailleres, Aurelie Pastant, Philippe Rouanet, Pascal Fenoglietto, Jean-Bernard Dubois and Marian Gutowski
    Citation: Radiation Oncology 2013 8:191
  25. The prognosis of prostate cancer patients with lymph node metastases so small they can only be visualized by new imaging techniques as MR lymphography (MRL) is unknown. The purpose of this study was to investi...

    Authors: Hanneke JM Meijer, Oscar A Debats, Emile NJTh van Lin, Johannes Alfred Witjes, Johannes HAM Kaanders and Jelle O Barentsz
    Citation: Radiation Oncology 2013 8:190
  26. The vascular endothelial cells are important targets of radiotherapy, which may be involved in the pathogenesis of radiation pneumonitis (RP). This study investigated the variations of circulating endothelial ...

    Authors: Yunfang Liu, Tingyi Xia, Wenjun Zhang, Yongjie Zhong, Luhua Zhang, Xuan Wang and Huiming Yu
    Citation: Radiation Oncology 2013 8:189
  27. Increasing use of IMRT to treat breast and prostate cancers at high risk of regional nodal spread relies on accurate contouring of targets and organs at risk, which is subject to significant inter- and intra-o...

    Authors: Vikram M Velker, George B Rodrigues, Robert Dinniwell, Jeremiah Hwee and Alexander V Louie
    Citation: Radiation Oncology 2013 8:188
  28. Neurocognitive decline observed after radiotherapy (RT) for brain tumors in long time survivors is attributed to radiation exposure of the hippocampus and the subventricular zone (SVZ). The potential of sparin...

    Authors: Julia Oehler, Tim Brachwitz, Thomas G Wendt, Nico Banz, Mario Walther and Tilo Wiezorek
    Citation: Radiation Oncology 2013 8:187
  29. In-room cone-beam computerized tomography (CBCT) imaging is a promising method to reduce setup errors, especially in organs such as the bladder that often have large intrafractional variations due to organ mov...

    Authors: Kentaro Nishioka, Shinichi Shimizu, Rumiko Kinoshita, Tetsuya Inoue, Shunsuke Onodera, Koichi Yasuda, Keiichi Harada, Yukiko Nishikawa, Rikiya Onimaru and Hiroki Shirato
    Citation: Radiation Oncology 2013 8:185
  30. Hodgkin disease (HD) and medulloblastoma (MB) are common malignancies found in children and young adults, and radiotherapy is part of the standard treatment. It was reported that these patients who received ra...

    Authors: Rui Zhang, Rebecca M Howell, Kenneth Homann, Annelise Giebeler, Phillip J Taddei, Anita Mahajan and Wayne D Newhauser
    Citation: Radiation Oncology 2013 8:184
  31. To evaluate the interobserver variability of gross tumor volume (GTV) - delineation of Dominant Intraprostatic Lesions (DIPL) in patients with prostate cancer using published MRI criteria for multiparametric M...

    Authors: Hans Christian Rischke, Ursula Nestle, Tobias Fechter, Christian Doll, Natalja Volegova-Neher, Karl Henne, Jutta Scholber, Stefan Knippen, Simon Kirste, Anca L Grosu and Cordula A Jilg
    Citation: Radiation Oncology 2013 8:183
  32. Tomotherapy for intensity-modulated radiation has been demonstrated to reduce unnecessary irradiations to adjacent organs at risk (OARs). The purpose of this study was to compare the dosimetric parameters betw...

    Authors: Mina Yu, Joo Hwan Lee, Hong Seok Jang, Dong Min Jeon, Jae Suk Cheon, Hyo Chun Lee and Jong Hoon Lee
    Citation: Radiation Oncology 2013 8:181
  33. This study compared manually delineated gross tumour volume (GTV) and automatically generated biological tumour volume (BTV) based on fluoro-deoxy-glucose (FDG) positron emission tomography (PET)/CT to assess ...

    Authors: Maximilian Niyazi, Sonja Landrock, Andreas Elsner, Farkhad Manapov, Marcus Hacker, Claus Belka and Ute Ganswindt
    Citation: Radiation Oncology 2013 8:180
  34. Low survival outcomes have been reported for the treatment of locally advanced non small cell lung cancer (LA-NSCLC) with the standard of care treatment of concurrent chemoradiation (cCRT). We present our expe...

    Authors: Sana D Karam, Zachary D Horne, Robert L Hong, Don McRae, David Duhamel and Nadim M Nasr
    Citation: Radiation Oncology 2013 8:179
  35. Radioresistance is the common cause for radiotherapy failure in non-small cell lung cancer (NSCLC), and the degree of radiosensitivity of tumor cells is different during different cell cycle phases. The object...

    Authors: Rubo Cao, Qian Ding, Pindong Li, Jun Xue, Zhenwei Zou, Jing Huang and Gang Peng
    Citation: Radiation Oncology 2013 8:178
  36. To determine prostate volume (Pvol) changes at 3 different time points during the course of I125 permanent seed brachytherapy (PB). To assess the impact of these changes on acute urinary retention (AUR) and dosim...

    Authors: Ciprian Chira, Guila Delouya, Sandra Larrivée, Jean-Francois Carrier and Daniel Taussky
    Citation: Radiation Oncology 2013 8:177
  37. To assess the dosimetric effect induced by inter-observer variability in target definition for 3D-conformal RT (3DCRT) and volumetric modulated arc therapy by RapidArc (RA) techniques for rectal cancer treatment.

    Authors: Francesca Lobefalo, Mario Bignardi, Giacomo Reggiori, Angelo Tozzi, Stefano Tomatis, Filippo Alongi, Antonella Fogliata, Anna Gaudino, Piera Navarria, Luca Cozzi, Marta Scorsetti and Pietro Mancosu
    Citation: Radiation Oncology 2013 8:176
  38. Local ablative therapies such as stereotactically guided single-dose radiotherapy or helical intensity-modulated radiotherapy (tomotherapy) with high single-doses are successfully applied in many centers in pa...

    Authors: Daniel Habermehl, Klaus K Herfarth, Justo Lorenzo Bermejo, Holger Hof, Stefan Rieken, Sabine Kuhn, Thomas Welzel, Jürgen Debus and Stephanie E Combs
    Citation: Radiation Oncology 2013 8:175
  39. Tumor human papillomavirus (HPV) status has emerged as one of the most powerful prognostic factors for disease control and survival in patients with oropharyngeal squamous cell carcinoma (OPSCC). We reviewed o...

    Authors: Trevor J Bledsoe, Anisha R Noble, Grant K Hunter, Lisa A Rybicki, Aaron Hoschar, Deborah J Chute, Jerrold P Saxton, John F Greskovich, David J Adelstein and Shlomo A Koyfman
    Citation: Radiation Oncology 2013 8:174
  40. Accumulating evidence suggests that brachial plexopathy following head and neck cancer radiotherapy may be underreported and that this toxicity is associated with a dose–response. Our purpose was to determine ...

    Authors: Robert W Mutter, Benjamin H Lok, Pinaki R Dutta, Nadeem Riaz, Jeremy Setton, Sean L Berry, Anuj Goenka, Zhigang Zhang, Shyam S Rao, Suzanne L Wolden and Nancy Y Lee
    Citation: Radiation Oncology 2013 8:173
  41. A review of planning studies was undertaken to evaluate estimated risks of radiation induced second primary cancers (RISPC) associated with different prostate radiotherapy techniques for localised prostate can...

    Authors: Louise Murray, Ann Henry, Peter Hoskin, Frank-Andre Siebert and Jack Venselaar
    Citation: Radiation Oncology 2013 8:172
  42. To evaluate the feasibility and early side effects of a short course hypo-fractionated SBRT programme with Volumetric Modulated Arc Therapy (VMAT) and Flattening Filter Free (FFF) beams.

    Authors: Filippo Alongi, Luca Cozzi, Stefano Arcangeli, Cristina Iftode, Tiziana Comito, Elisa Villa, Francesca Lobefalo, Pierina Navarria, Giacomo Reggiori, Pietro Mancosu, Elena Clerici, Antonella Fogliata, Stefano Tomatis, Gianluigi Taverna, Pierpaolo Graziotti and Marta Scorsetti
    Citation: Radiation Oncology 2013 8:171
  43. The ideal prostate-specific antigen (PSA) doubling time (PSADT) threshold for identifying patients at high-risk for poor clinical outcome following salvage radiation therapy (SRT) has not been well established...

    Authors: William C Jackson, Skyler B Johnson, Darren Li, Corey Foster, Benjamin Foster, Yeohan Song, Matthew Schipper, Mark Shilkrut, Howard M Sandler, Todd M Morgan, Ganesh S Palapattu, Daniel A Hamstra and Felix Y Feng
    Citation: Radiation Oncology 2013 8:170
  44. To analyze the longitudinal length accuracy of gross tumor volume (GTV) delineation with diffusion weighted magnetic resonance imaging for esophageal squamous cell carcinoma (SCC).

    Authors: Dong-Liang Hou, Gao-Feng Shi, Xian-Shu Gao, Junichi Asaumi, Xue-Ying Li, Hui Liu, Chen Yao and Joe Y Chang
    Citation: Radiation Oncology 2013 8:169
  45. Lung stereotactic ablative radiotherapy (SABR) has recently become more common in the management of patients with early-stage non-small cell lung cancer (NSCLC) and metastatic lung lesions who are not surgical...

    Authors: Michael C Stauder, Jessica W Rooney, Michelle A Neben-Wittich, Yolanda I Garces and Kenneth R Olivier
    Citation: Radiation Oncology 2013 8:167
  46. To evaluate the therapeutic benefit of 3D-image-guided high-dose-rate intracavitary brachytherapy (3D-image-guided HDR-BT) used as a salvage treatment of intensity modulated radiation therapy (IMRT) in patient...

    Authors: Yu Feng Ren, Xin Ping Cao, Jia Xu, Wei Jun Ye, Yuan Hong Gao, Bin S Teh and Bi Xiu Wen
    Citation: Radiation Oncology 2013 8:165

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