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  1. Whether adjuvant chemotherapy (AC) after concurrent chemoradiotherapy (CCRT) could provide benefit to esophageal squamous cell carcinoma (ESCC) patients is controversial. Therefore, we decided to investigate t...

    Authors: Ao Liu, Yalin Wang, Xin Wang, Liqiong Zhu, Yu Nie and Minghuan Li
    Citation: Radiation Oncology 2021 16:195
  2. Stereotactic body radiotherapy (SBRT) is increasingly used for treatment of liver tumors but the effect on metabolic liver function in surrounding tissue is largely unknown. Using 2-deoxy-2-[18F]fluoro-d-galactos...

    Authors: Michael Sørensen, Mette Marie Fode, Jørgen Baltzer Petersen, Marianne Ingerslev Holt and Morten Høyer
    Citation: Radiation Oncology 2021 16:192
  3. To determine the most appropriate radiologic criteria of metastatic retropharyngeal lymph nodes (RLNs) in patients with maxillary sinus cancer (MSC).

    Authors: Yasuo Kosugi, Michimasa Suzuki, Mitsuhisa Fujimaki, Shinichi Ohba, Fumihiko Matsumoto, Yoichi Muramoto, Terufumi Kawamoto, Masaki Oshima, Naoto Shikama and Keisuke Sasai
    Citation: Radiation Oncology 2021 16:190
  4. MR-guided online adaptive stereotactic body radiation therapy (SBRT) for prostate cancer aims to reduce toxicity by full compensation of interfractional uncertainties. However, the process of online adaptation...

    Authors: J. Schaule, M. Chamberlain, L. Wilke, M. Baumgartl, J. Krayenbühl, M. Zamburlini, M. Mayinger, N. Andratschke, S. Tanadini-Lang and M. Guckenberger
    Citation: Radiation Oncology 2021 16:189
  5. In radiotherapy, respiratory-induced tumor motion is typically measured using a single four-dimensional computed tomography acquisition (4DCT). Irregular breathing leads to inaccurate motion estimates, potenti...

    Authors: Duncan den Boer, Johannes K. Veldman, Geertjan van Tienhoven, Arjan Bel and Zdenko van Kesteren
    Citation: Radiation Oncology 2021 16:188
  6. Pelvic radiotherapy is the key treatment for pelvic malignancies, usually including pelvic primary tumour lesions and lymphatic drainage areas in the pelvic region. Therefore, the intestinal tract in the radia...

    Authors: Lina Wang, Xiaohu Wang, Guangwen Zhang, Yan Ma, Qiuning Zhang, Zheng Li, Juntao Ran, Xiaoming Hou, Yichao Geng, Zheng Yang, Shuangwu Feng, Chengcheng Li and Xueshan Zhao
    Citation: Radiation Oncology 2021 16:187
  7. To develop a risk model based on dosimetric metrics to predict local recurrence in nasopharyngeal carcinoma (NPC) patients treated with intensive modulated radiation therapy (IMRT).

    Authors: Wenjun Liao, Jinlan He, Zijian Liu, Maolang Tian, Jiangping Yang, Jiaqi Han and Jianghong Xiao
    Citation: Radiation Oncology 2021 16:186
  8. To investigate the relationship between radiotherapy (RT) and the risk of cerebrovascular mortality (CVM) in head and neck cancer (HNC) survivors aged ≥ 65 years.

    Authors: Qing-Song He, Zhen-Ping Wang, Zhao-Jun Li, Ping Zhou, Chen-Lu Lian, San-Gang Wu and Si-Fang Chen
    Citation: Radiation Oncology 2021 16:185
  9. The role of postoperative radiotherapy (PORT) in cardiovascular-pulmonary disease mortality in patients with stage IIIA-N2 resected non-small cell lung cancer (NSCLC) remains uncertain. The purpose of this pop...

    Authors: Xia Wang, Jiaqi Song, Jie Long, Zhimin Zeng and Anwen Liu
    Citation: Radiation Oncology 2021 16:184
  10. Hybrid magnetic resonance (MR)-guided linear accelerators represent a new horizon in the field of radiation oncology. By harnessing the favorable combination of on-board MR-imaging with the possibility to dail...

    Authors: Francesco Cuccia, Filippo Alongi, Claus Belka, Luca Boldrini, Juliane Hörner-Rieber, Helen McNair, Michele Rigo, Maartje Schoenmakers, Maximilian Niyazi, Judith Slagter, Claudio Votta and Stefanie Corradini
    Citation: Radiation Oncology 2021 16:183
  11. We aimed to assess the feasibility of a dose painting (DP) procedure, known as simultaneous integrated boost intensity modulated radiation Therapy (SIB-IMRT), for treating prostate cancer with dominant intrapr...

    Authors: Seyed Masoud Rezaeijo, Bijan Hashemi, Bahram Mofid, Mohsen Bakhshandeh, Arash Mahdavi and Mohammad Saber Hashemi
    Citation: Radiation Oncology 2021 16:182
  12. In patients with stage III melanoma, the use of adjuvant radiation therapy (RT) after lymph node dissection (LND) may be currently considered in selected high-risk patients to improve tumor control. Melanomas ...

    Authors: Adam R. Wolfe, Priyanka Chablani, Michael R. Siedow, Eric D. Miller, Steve Walston, Kari L. Kendra, Evan Wuthrick and Terence M. Williams
    Citation: Radiation Oncology 2021 16:181
  13. To report preliminary data on treatment outcome and compliance to dose-intensified organ sparing SBRT for prostate cancer using a novel electromagnetic transmitter-based tracking system (RayPilot® System) to a...

    Authors: Raffaella Lucchini, Denis Panizza, Riccardo Ray Colciago, Veronica Vernier, Martina Camilla Daniotti, Valeria Faccenda and Stefano Arcangeli
    Citation: Radiation Oncology 2021 16:180
  14. The purpose of the study was to assess the uterus motions and bladder volume changes of fractional movements in cervical sites throughout the external beam radiotherapy (EBRT) treatment.

    Authors: Xu Li, Lizhen Wang, Zhen Cui, Yukun Li, Pei Liu, Yungang Wang, Jinhong Zhu, Jianmin Zhu, Yong Yin and Zhenjiang Li
    Citation: Radiation Oncology 2021 16:179

    The Correction to this article has been published in Radiation Oncology 2021 16:200

  15. There is limited evidence concerning radiotherapy for painful lymph node metastases (PLM). We evaluated the effectiveness of radiotherapy for PLM using the International Consensus Endpoint in a subgroup analys...

    Authors: Kohsei Yamaguchi, Tetsuo Saito, Ryo Toya, Etsushi Tomitaka, Tomohiko Matsuyama, Yoshiyuki Fukugawa, Takahiro Watakabe, Hirohito Otsuka and Natsuo Oya
    Citation: Radiation Oncology 2021 16:178
  16. The SWORD trial is the first multicenter, single arm, phase II study assessing the safety and efficacy of a PD-1 inhibitor (Sintilimab), stereotactic body radiotherapy (SBRT) and granulocyte–macrophage colony ...

    Authors: Jianjiao Ni, Yue Zhou, Lin Wu, Xinghao Ai, Xiaorong Dong, Qian Chu, Chengbo Han, Xiaofei Wang and Zhengfei Zhu
    Citation: Radiation Oncology 2021 16:177
  17. The aim of this study was to compare the pattern of intra-patient spread of lymph-node (LN)-metastases within the mediastinum as assessed by 18F-FDG PET/CT and systematic endobronchial ultrasound-guided transbron...

    Authors: Maja Guberina, Kaid Darwiche, Hubertus Hautzel, Christoph Pöttgen, Nika Guberina, Thomas Gauler, Till Ploenes, Lale Umutlu, Dirk Theegarten, Clemens Aigner, Wilfried E. E. Eberhardt, Martin Metzenmacher, Marcel Wiesweg, Rüdiger Karpf-Wissel, Martin Schuler, Ken Herrmann…
    Citation: Radiation Oncology 2021 16:176
  18. Contour delineation, a crucial process in radiation oncology, is time-consuming and inaccurate due to inter-observer variation has been a critical issue in this process. An atlas-based automatic segmentation w...

    Authors: Yuka Urago, Hiroyuki Okamoto, Tomoya Kaneda, Naoya Murakami, Tairo Kashihara, Mihiro Takemori, Hiroki Nakayama, Kotaro Iijima, Takahito Chiba, Junichi Kuwahara, Shouichi Katsuta, Satoshi Nakamura, Weishan Chang, Hidetoshi Saitoh and Hiroshi Igaki
    Citation: Radiation Oncology 2021 16:175
  19. Proton beam therapy is a well-established treatment option for patients with uveal melanoma (UM). The treatment procedure, in general, includes placing radiopaque clips to ensure exact eye-positioning during r...

    Authors: Johannes Gollrad, Christopher Rabsahl, Aline-Isabel Riechardt, Jens Heufelder, Andrea Stroux, Ute Goerling, Antonia Joussen, Volker Budach and Dirk Boehmer
    Citation: Radiation Oncology 2021 16:174
  20. This study aimed to investigate the effect of abdominal compression on tumour motion and target volume and to determine suitable planning target volume (PTV) margins for patients treated with lung stereotactic...

    Authors: Yuanjun Qi, Jianbin Li, Yingjie Zhang, Qian Shao, Xijun Liu, Fengxiang Li, Jinzhi Wang, Zhenxiang Li and Wei Wang
    Citation: Radiation Oncology 2021 16:173
  21. To investigate risk factors for developing radiation-associated facial lymphedema (FL) in nasopharyngeal carcinoma (NPC) patients after concurrent chemoradiation (CCRT).

    Authors: Donghyun Kim, Jiho Nam, Wontaek Kim, Dahl Park, Jihyeon Joo, Hosang Jeon and Yongkan Ki
    Citation: Radiation Oncology 2021 16:172
  22. To compare the dosimetric, normal tissue complication probability (NTCP), secondary cancer complication probabilities (SCCP), and excess absolute risk (EAR) differences of volumetric modulated arc therapy (VMA...

    Authors: Yun Zhang, Yuling Huang, Shenggou Ding, Xingxing Yuan, Yuxian Shu, Jinhui Liang, Qingfeng Mao, Chunling Jiang and Jingao Li
    Citation: Radiation Oncology 2021 16:171
  23. Stereotactic Body Radiotherapy (SBRT) has shown effectiveness in treating bone metastases to alleviate pain. The benefit of SBRT may be further harnessed especially when radiating disease from primary malignan...

    Authors: Eric K. Nguyen, Kimmen Quan, Sameer Parpia, Stephan Tran and Anand Swaminath
    Citation: Radiation Oncology 2021 16:170
  24. To evaluate the combined effect of rotational error and dose gradient on target dose coverage in frameless stereotactic radiotherapy.

    Authors: Jai-Woong Yoon, Soah Park, Kwang-Ho Cheong, Sei-Kwon Kang and Tae Jin Han
    Citation: Radiation Oncology 2021 16:169
  25. The objective of this study was to analyze the amplitude of translational and rotational movements occurring during stereotactic body radiotherapy (SBRT) of spinal metastases in two different positioning devic...

    Authors: Ahmed Hadj Henni, David Gensanne, Maximilien Roge, Chantal Hanzen, Guillaume Bulot, Elyse Colard and Sebastien Thureau
    Citation: Radiation Oncology 2021 16:168
  26. To evaluate the influence of target dose heterogeneity on normal tissue dose sparing for peripheral lung tumor stereotactic body radiation therapy (SBRT).

    Authors: Zhigong Wei, Xingchen Peng, Yan Wang, Lianlian Yang, Ling He, Zheran Liu, Jingjing Wang, Xiaoli Mu, Ruidan Li and Jianghong Xiao
    Citation: Radiation Oncology 2021 16:167
  27. Most anterior visual pathway meningiomas (AVPM) are benign and slow-growing, but these tumors may affect visual functions, including visual acuity (VA) and visual field (VF). Due to location, most are treated ...

    Authors: Leor Zach, Amir Agami, Orit Furman, Moshe Attia, Zvi Cohen, Iris Ben-Bassat Mizrachi, Guy Tam, Zion Zibly, Ouzi Nissim, Roberto Spiegelmann and Ruth Huna-Baron
    Citation: Radiation Oncology 2021 16:166
  28. Multifocal manifestation of high-grade glioma is a rare disease with very unfavourable prognosis. The pathogenesis of multifocal glioma and pathophysiological differences to unifocal glioma are not fully under...

    Authors: Daniel Felix Fleischmann, Rudolph Schön, Stefanie Corradini, Raphael Bodensohn, Indrawati Hadi, Jan Hofmaier, Robert Forbrig, Niklas Thon, Mario Dorostkar, Claus Belka and Maximilian Niyazi
    Citation: Radiation Oncology 2021 16:165
  29. The benefit and the risk profile of Gamma Knife radiosurgery (GKRS) for intracerebral cavernoma remains incompletely defined in part due to the natural history of low incidence of bleeding and spontaneous regr...

    Authors: Chiung-Chyi Shen, Ming Hsi Sun, Meng-Yin Yang, Weir-Chiang You, Meei-Ling Sheu, Yen-Ju Chen, Ying Ju Chen, Jason Sheehan and Hung-Chuan Pan
    Citation: Radiation Oncology 2021 16:164
  30. Advances in multi-modality treatment of locally advanced rectal cancer (LARC) have resulted in low local recurrence rates, but around 30% of patients will still die from distant metastatic disease. In parallel...

    Authors: Catherine R. Hanna, Sean M. O’Cathail, Janet S. Graham, Mark Saunders, Leslie Samuel, Mark Harrison, Lynsey Devlin, Joanne Edwards, Daniel R. Gaya, Caroline A. Kelly, Liz-Anne Lewsley, Noori Maka, Paula Morrison, Louise Dinnett, Susan Dillon, Jacqueline Gourlay…
    Citation: Radiation Oncology 2021 16:163

    The Correction to this article has been published in Radiation Oncology 2021 16:230

  31. Authors: Heather Miller, Koji Matsuo, Lynda D. Roman, Annie A. Yessaian, Huyen Q. Pham, Marianne Hom, Antonio Castaneda, Anthony Pham, Omar Ragab, Laila Muderspach, Marcia Ciccone and Laurie L. Brunette
    Citation: Radiation Oncology 2021 16:162

    The original article was published in Radiation Oncology 2021 16:123

  32. Gastric bleeding negatively impacts the quality of life of patients with unresectable advanced gastric cancer and is frequently lethal. We investigated the efficacy of RT for palliation of gastric bleeding fro...

    Authors: Joongyo Lee, Hwa Kyung Byun, Woong Sub Koom, Yong Chan Lee and Jinsil Seong
    Citation: Radiation Oncology 2021 16:161
  33. Disruption of the tumor-brain barrier in meningioma is a crucial factor in peritumoral brain edema (PTBE). We previously reported the possible effect of osteoporosis on the integrity of the arachnoid trabecula...

    Authors: Sang Mook Kang, Jae Min Kim, Jin Hwan Cheong, Je Il Ryu, Yu Deok Won, Young Soo Kim and Myung-Hoon Han
    Citation: Radiation Oncology 2021 16:160
  34. Invasiveness is a major factor contributing to metastasis of tumour cells. Given the broad variety and plasticity of invasion mechanisms, assessing potential metastasis-promoting effects of irradiation for spe...

    Authors: Jia Mei, Claudia Böhland, Anika Geiger, Iris Baur, Kristina Berner, Steffen Heuer, Xue Liu, Laura Mataite, M. Camila Melo-Narváez, Erdem Özkaya, Anna Rupp, Christian Siebenwirth, Felix Thoma, Matthias F. Kling and Anna A. Friedl
    Citation: Radiation Oncology 2021 16:159
  35. To evaluate the dosimetric and biological benefits of the fixed-jaw (FJ) intensity-modulated radiation therapy (IMRT) technique for patients with T-shaped esophageal cancer.

    Authors: Hua Chen, Ying Huang, Hao Wang, Yan Shao, Ning J. Yue, Hengle Gu, Yanhua Duan, Aihui Feng and Zhiyong Xu
    Citation: Radiation Oncology 2021 16:158
  36. Patients with low-grade gliomas (LGGs) harboring O6-methylguanine-DNA methyltransferase promoter nonmethylation (MGMT-non-pM) have a particularly short survival and are great resistance to chemotherapy. The objec...

    Authors: Yanwei Liu, Yanong Li, Peng Wang, Li Chen, Jin Feng and Xiaoguang Qiu
    Citation: Radiation Oncology 2021 16:157
  37. To investigate the treatment outcomes of passive scattering proton beam therapy using stereotactic ablative radiotherapy (SABR) or hypofractionated radiation therapy (RT) for inoperable patients or those who r...

    Authors: Unurjargal Bayasgalan, Sung Ho Moon, Jong Hwi Jeong, Tae Hyun Kim, Kwan Ho Cho and Yang-Gun Suh
    Citation: Radiation Oncology 2021 16:155
  38. Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction mo...

    Authors: Sang Hee Ahn, EunSook Kim, Chankyu Kim, Wonjoong Cheon, Myeongsoo Kim, Se Byeong Lee, Young Kyung Lim, Haksoo Kim, Dongho Shin, Dae Yong Kim and Jong Hwi Jeong
    Citation: Radiation Oncology 2021 16:154
  39. Common symptoms of oesophageal cancer are dysphagia, pain, and bleeding. These symptoms can be relieved with palliative radiotherapy. The aim of this study was to analyse the outcome of two different palliativ...

    Authors: Halla Sif Ólafsdóttir, Fredrik Klevebro, Nelson Ndegwa and Gabriella Alexandersson von Döbeln
    Citation: Radiation Oncology 2021 16:153
  40. Treatment-related white blood cell (WBC) toxicity has been associated with an inferior prognosis in different malignancies, including anal cancer. The aim of the present study was to investigate predictors of ...

    Authors: Martin P. Nilsson, Anders Johnsson and Jonas Scherman
    Citation: Radiation Oncology 2021 16:152
  41. Meningiomas express the somatostatin receptor (SSTR), which normal bone and brain lack. PET imaging with SSTR ligands such as 68 Ga-DOTATATE have been recently shown to aid in the imaging and identification of me...

    Authors: Emily S. Kowalski, Rahul Khairnar, Anton A. Gryaznov, Vivek Kesari, Antony Koroulakis, Prashant Raghavan, Wengen Chen, Graeme Woodworth and Mark Mishra
    Citation: Radiation Oncology 2021 16:151
  42. Inter-modality image registration between computed tomography (CT) and magnetic resonance (MR) images is associated with systematic uncertainties and the magnitude of these uncertainties is not well documented...

    Authors: Emilia Persson, Sevgi Emin, Jonas Scherman, Christian Jamtheim Gustafsson, Patrik Brynolfsson, Sofie Ceberg, Adalsteinn Gunnlaugsson and Lars E. Olsson
    Citation: Radiation Oncology 2021 16:150
  43. To compare the clinical outcomes of stereotactic body radiation therapy (SBRT) and fractionated radiation therapy (FRT) for primary liver cancer with portal vein tumor thrombus (PVTT).

    Authors: Sujing Zhang, Li He, Changwen Bo, Shufang Yang, Yonghui An, Na Li, Yingchun Zhao, Liping Zhao, Wenhua Ma and Zheng Zheng
    Citation: Radiation Oncology 2021 16:149
  44. The purpose of this study was to analyze the treatment efficacy and safety of stereotactic ablative body radiotherapy (SABR) boost for cervical cancer patients not amenable to brachytherapy.

    Authors: Tae Hoon Lee, Changhoon Song, In Ah Kim, Jae-Sung Kim, Yong Beom Kim, Kidong Kim, Jae Hong No, Dong Hoon Suh, Jin-Beom Chung and Keun-Yong Eom
    Citation: Radiation Oncology 2021 16:148
  45. Image guidance in radiation oncology has resulted in significant improvements in the accuracy and precision of radiation therapy (RT). Recently, the resolution and quality of cone beam computed tomography (CBC...

    Authors: Whitney Sumner, Sangwoo S. Kim, Lucas Vitzthum, Kevin Moore, Todd Atwood, James Murphy, Sayuri Miyauchi, Joseph A. Califano, Loren K. Mell, Arno J. Mundt and Andrew B. Sharabi
    Citation: Radiation Oncology 2021 16:147
  46. A range pull-back device, such as a machine-related range shifter (MRS) or a universal patient-related range shifter (UPRS), is needed in pencil beam scanning technique to treat shallow tumors.

    Authors: Haibo Lin, Chengyu Shi, Sheng Huang, Jiajian Shen, Minglei Kang, Qing Chen, Huifang Zhai, James McDonough, Zelig Tochner, Curtiland Deville, Charles B. Simone II and Stefan Both
    Citation: Radiation Oncology 2021 16:146
  47. Hypofractionation is increasingly being applied in radiotherapy for prostate cancer, requiring higher accuracy of daily treatment deliveries than in conventional image-guided radiotherapy (IGRT). Different ada...

    Authors: Miriam Eckl, Gustavo R. Sarria, Sandra Springer, Marvin Willam, Arne M. Ruder, Volker Steil, Michael Ehmann, Frederik Wenz and Jens Fleckenstein
    Citation: Radiation Oncology 2021 16:145

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