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  1. Radiation medicine has previously utilized planning methods based primarily on anatomic and volumetric imaging technologies such as CT (Computerized Tomography), ultrasound, and MRI (Magnetic Resonance Imaging...

    Authors: Nidhi Sharma, Donald Neumann and Roger Macklis

    Citation: Radiation Oncology 2008 3:25

    Content type: Review

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  2. To expand and test the dosimetric procedure, known as GLAaS, for amorphous silicon detectors to the RapidArc intensity modulated arc delivery with Varian infrastructures and to test the RapidArc dosimetric rel...

    Authors: Giorgia Nicolini, Eugenio Vanetti, Alessandro Clivio, Antonella Fogliata, Stine Korreman, Jiri Bocanek and Luca Cozzi

    Citation: Radiation Oncology 2008 3:24

    Content type: Methodology

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  3. To use amifostine concurrently with radiochemotherapy (CT-RT) or radiotherapy (RT) alone in order to prevent dry eye syndrome in patients with malignancies located in the fronto-orbital region.

    Authors: David Goldblum, Pirus Ghadjar, Juergen Curschmann, Richard Greiner and Daniel Aebersold

    Citation: Radiation Oncology 2008 3:22

    Content type: Research

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  4. Prostate cancer is the leading form of cancer diagnosed among North American men. Most patients present with localized disease, which can be effectively treated with a variety of different modalities. These ar...

    Authors: Kurian Jones Joseph, Riaz Alvi, David Skarsgard, Jon Tonita, Nadeem Pervez, Cormac Small and Patricia Tai

    Citation: Radiation Oncology 2008 3:20

    Content type: Research

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  5. As the majority of prostate cancers (PC) express estrogen receptors, we evaluated the combination of radiation and estrogenic stimulation (estrogen and genistein) on the radiosensitivity of PC cells in vitro.

    Authors: Robert Michael Hermann, Hendrik Andreas Wolff, Hubertus Jarry, Paul Thelen, Carsten Gruendker, Margret Rave-Fraenk, Heinz Schmidberger and Hans Christiansen

    Citation: Radiation Oncology 2008 3:19

    Content type: Research

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  6. Radiotherapy (RT) has become an important treatment modality in pediatric oncology, but its delivery to young children with cancer is challenging and general anesthesia is often needed.

    Authors: Sonja Haeberli, Michael A Grotzer, Felix K Niggli, Markus A Landolt, Claudia Linsenmeier, Roland A Ammann and Nicole Bodmer

    Citation: Radiation Oncology 2008 3:17

    Content type: Research

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  7. Hypofractionated radiotherapy has been used for the treatment of AVMs and brain metastases. Hypofractionation necessitates the use of a relocatable stereotactic frame that has to be applied on several occasion...

    Authors: Peter Lindvall, Per Bergström, Per-Olov Löfroth, Roger Henriksson and A Tommy Bergenheim

    Citation: Radiation Oncology 2008 3:16

    Content type: Research

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  8. We evaluated the acute and late toxicity after high-dose intensity-modulated radiotherapy (IMRT) with fiducial marker-based position verification for prostate cancer. Between 2001 and 2004, 331 patients with p...

    Authors: Irene M Lips, Homan Dehnad, Carla H van Gils, Arto E Boeken Kruger, Uulke A van der Heide and Marco van Vulpen

    Citation: Radiation Oncology 2008 3:15

    Content type: Short report

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  9. The shape of the dose-response curve at low doses differs from the linear quadratic model. The effect of a radio-adaptive response is the centre of many studies and well known inspite that the clinical applica...

    Authors: Silke B Schwarz, Pamela M Schaffer, Ulrike Kulka, Birgit Ertl-Wagner, Roswitha Hell and Moshe Schaffer

    Citation: Radiation Oncology 2008 3:12

    Content type: Research

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  10. Late effects after radiotherapy in childhood and adolescence have mainly been characterized retrospectively with small patient numbers. However, these analyses are limited due to little information regarding o...

    Authors: Tobias Bolling, Andreas Schuck, Hildegard Pape, Christian Rube, Barbara Pollinger, Beate Timmermann, Rolf D Kortmann, Karin Dieckmann and Normann Willich

    Citation: Radiation Oncology 2008 3:10

    Content type: Study protocol

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  11. To report our experience treating soft tissue sarcoma (STS) with high dose rate brachytherapy alone (HBRT) or in combination with external beam radiotherapy (EBRT) in pediatric patients.

    Authors: Gustavo A Viani, Paulo E Novaes, Alexandre A Jacinto, Celia B Antonelli, Antonio Cassio A Pellizzon, Elisa Y Saito and João V Salvajoli

    Citation: Radiation Oncology 2008 3:9

    Content type: Research

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  12. To assess whether an expanded (five level) risk stratification system can be used to identify the sub-group of intermediate risk patients with prostate cancer who benefit from combining androgen deprivation th...

    Authors: Matthew Beasley, Scott G Williams and Tom Pickles

    Citation: Radiation Oncology 2008 3:8

    Content type: Research

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  13. The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes. The purpose of this st...

    Authors: Hans Paul van der Laan, Wil V Dolsma, John H Maduro, Erik W Korevaar and Johannes A Langendijk

    Citation: Radiation Oncology 2008 3:6

    Content type: Research

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  14. The aim of this treatment planning study was to investigate the potential advantages of intensity-modulated (IM) proton therapy (IMPT) compared with IM photon therapy (IMRT) in nasopharyngeal carcinoma (NPC).

    Authors: Zahra Taheri-Kadkhoda, Thomas Björk-Eriksson, Simeon Nill, Jan J Wilkens, Uwe Oelfke, Karl-Axel Johansson, Peter E Huber and Marc W Münter

    Citation: Radiation Oncology 2008 3:4

    Content type: Research

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  15. To evaluate the risk of rectal, bladder and small bowel toxicity in intensity modulated radiation therapy (IMRT) of the prostate only compared to additional irradiation of the pelvic lymphatic region.

    Authors: Matthias Guckenberger, Kurt Baier, Anne Richter, Dirk Vordermark and Michael Flentje

    Citation: Radiation Oncology 2008 3:3

    Content type: Research

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  16. Androgen suppression treatment (AST) might increase the risk of cardiac morbidity in prostate cancer patients. Possible explanations were provided, however, they disregard the potential contribution of prophyl...

    Authors: Carsten Nieder, Adam Pawinski, Nicolaus H Andratschke and Michael Molls

    Citation: Radiation Oncology 2008 3:2

    Content type: Research

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  17. To compare two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the setting of hypofractionated high-risk prostate cancer treatment.

    Authors: Jasper Yuen, George Rodrigues, Kristina Trenka, Terry Coad, Slav Yartsev, David D'Souza, Michael Lock and Glenn Bauman

    Citation: Radiation Oncology 2008 3:1

    Content type: Research

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  18. Radiation dermatitis is a common side effect of radiation therapy (RT). In severe cases, RT must be interrupted until the skin heals, which can compromise treatment. The purpose of the study was to compare an ...

    Authors: Thomas E Merchant, Christina Bosley, Julie Smith, Pam Baratti, David Pritchard, Tina Davis, Chenghong Li and Xiaoping Xiong

    Citation: Radiation Oncology 2007 2:45

    Content type: Research

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  19. Set-up errors are an inherent part of radiation treatment process. Coverage of target volume is a direct function of set-up margins, which should be optimized to prevent inadvertent irradiation of adjacent nor...

    Authors: Tejpal Gupta, Supriya Chopra, Avinash Kadam, Jai Prakash Agarwal, P Reena Devi, Sarbani Ghosh-Laskar and Ketayun Ardeshir Dinshaw

    Citation: Radiation Oncology 2007 2:44

    Content type: Short report

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  20. It is difficult to determine the most effective approach to patient education or tailor education interventions for patients in radiotherapy without tools that assess patients' specific radiation therapy infor...

    Authors: Georgia KB Halkett and Linda J Kristjanson

    Citation: Radiation Oncology 2007 2:43

    Content type: Research

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  21. The study summarised in this report aimed to investigate the interplay between fluence complexity, dose calculation algorithms, dose calculation spatial resolution and delivery characteristics (monitor units, ...

    Authors: Nicolini Giorgia, Fogliata Antonella, Vanetti Eugenio, Clivio Alessandro, Ammazzalorso Filippo and Cozzi Luca

    Citation: Radiation Oncology 2007 2:42

    Content type: Research

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  22. To compare the dosimetric advantage of three different intensity-modulated radiation therapy (IMRT) plans to a three dimensional (3D) conventional radiation treatment for anal cancer with regards to organs-at-...

    Authors: Cathy Menkarios, David Azria, Benoit Laliberté, Carmen Llacer Moscardo, Sophie Gourgou, Claire Lemanski, Jean-Bernard Dubois, Norbert Aillères and Pascal Fenoglietto

    Citation: Radiation Oncology 2007 2:41

    Content type: Research

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  23. The standard treatment of the axilla in breast cancer used to be an axillary lymph node dissection. An axillary lymph node dissection is known to give substantial risks of morbidity. In recent years the sentin...

    Authors: Patty H Spruit, Sabine Siesling, Marloes AG Elferink, Ernest JA Vonk and Carel JM Hoekstra

    Citation: Radiation Oncology 2007 2:40

    Content type: Research

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  24. Recent developments in radiotherapeutic technology have resulted in a new approach to treating patients with localized lung cancer. We report preliminary clinical outcomes using stereotactic radiosurgery with ...

    Authors: Brian T Collins, Kelly Erickson, Cristina A Reichner, Sean P Collins, Gregory J Gagnon, Sonja Dieterich, Don A McRae, Ying Zhang, Shadi Yousefi, Elliot Levy, Thomas Chang, Carlos Jamis-Dow, Filip Banovac and Eric D Anderson

    Citation: Radiation Oncology 2007 2:39

    Content type: Research

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  25. High-dose radiotherapy is standard treatment for patients with brain cancer. However, in preclinical research external beam radiotherapy is limited to heterotopic murine models– high-dose radiotherapy to the m...

    Authors: Joost JC Verhoeff, Lukas JA Stalpers, Annet W Coumou, Kees Koedooder, Cristina Lavini, Cornelis JF Van Noorden, Jaap Haveman, William P Vandertop and Wouter R van Furth

    Citation: Radiation Oncology 2007 2:38

    Content type: Research

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  26. Accelerated partial breast irradiation is commonly done with the MammoSite applicator, which requires symmetry to treat the patient. This paper describes three cases that were asymmetric when initially placed ...

    Authors: Subhakar Mutyala, Walter Choi, Atif J Khan, Ravi Yaparpalvi, Alexandra J Stewart and Phillip M Devlin

    Citation: Radiation Oncology 2007 2:37

    Content type: Research

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  27. To assess the feasibility and early toxicity of selective, IMRT-based dose escalation (simultaneous integrated boost) to biopsy proven dominant intra-prostatic lesions visible on MRI.

    Authors: Anurag K Singh, Peter Guion, Nancy Sears-Crouse, Karen Ullman, Sharon Smith, Paul S Albert, Gabor Fichtinger, Peter L Choyke, Sheng Xu, Jochen Kruecker, Bradford J Wood, Axel Krieger and Holly Ning

    Citation: Radiation Oncology 2007 2:36

    Content type: Research

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  28. To compare non coplanar field (NCF) with coplanar field (CF) -intensity-modulated radiotherapy (IMRT) planning for ethmoid cancer.

    Authors: Antoine Serre, Katia Idri, Pascal Fenoglietto, Norbert Ailleres, Lore Santoro, Claire Lemanski, Renaud Garrel, Marc Makeieff, Ali Allaw, Jean-Bernard Dubois and David Azria

    Citation: Radiation Oncology 2007 2:35

    Content type: Research

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  29. To evaluate the effects of direct machine parameter optimization in the treatment planning of intensity-modulated radiation therapy (IMRT) for hypopharyngeal cancer as compared to subsequent leaf sequencing in...

    Authors: Barbara Dobler, Fabian Pohl, Ludwig Bogner and Oliver Koelbl

    Citation: Radiation Oncology 2007 2:33

    Content type: Research

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  30. Respiration-gated radiotherapy (RGRT) can decrease treatment toxicity by allowing for smaller treatment volumes for mobile tumors. RGRT is commonly performed using external surrogates of tumor motion. We descr...

    Authors: John R van Sörnsen de Koste, Johan P Cuijpers, Frank GM de Geest, Frank J Lagerwaard, Ben J Slotman and Suresh Senan

    Citation: Radiation Oncology 2007 2:32

    Content type: Research

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  31. Oncological results of radiotherapy for locally advanced prostate cancer (PC) are significantly improved by simultaneous application of LHRH analoga (e.g. goserelin). As 85% of PC express LHRH receptors, we in...

    Authors: Robert M Hermann, Dag Schwarten, Stefanie Fister, Carsten Grundker, Margret Rave-Frank, Mirko Nitsche, Andrea Hille, Paul Thelen, Heinz Schmidberger and Hans Christiansen

    Citation: Radiation Oncology 2007 2:31

    Content type: Research

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  32. Smoking is an important risk factor for the development of cancer. Smoking during radiochemotherapy therapy may have a negative influence on prognosis. We evaluated the effect of smoking during radiochemothera...

    Authors: Sabine Kathrin Mai, Grit Welzel, Verena Haegele and Frederik Wenz

    Citation: Radiation Oncology 2007 2:30

    Content type: Research

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  33. To assess acute (primary endpoint) and late toxicity, quality of life (QOL), biochemical or clinical failure (secondary endpoints) of a hypofractionated IMRT schedule for prostate cancer (PC).

    Authors: Sara Junius, Karin Haustermans, Barbara Bussels, Raymond Oyen, Bianca Vanstraelen, Tom Depuydt, Jan Verstraete, Steven Joniau and Hendrik Van Poppel

    Citation: Radiation Oncology 2007 2:29

    Content type: Research

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  34. To investigate whether Radiation therapy (RT) should follow breast conserving surgery in women with ductal carcinoma in situ from breast cancer (DCIS) with objective of decreased mortality, invasive or non inv...

    Authors: Gustavo A Viani, Eduardo J Stefano, Sérgio L Afonso, Lígia I De Fendi, Francisco V Soares, Paola G Leon and Flavio S Guimarães

    Citation: Radiation Oncology 2007 2:28

    Content type: Research

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  35. Results of high-dose chemo-radiotherapy (CRT), using the treatment schedules of EORTC study 08972/22973 or radiotherapy (RT) alone were analyzed among all patients (pts) with Non Small Cell Lung Cancer (NSCLC)...

    Authors: Apollonia LJ Uitterhoeve, Mia GJ Koolen, Rob M van Os, Kees Koedooder, Marlou van de Kar, Bradley R Pieters and Caro CE Koning

    Citation: Radiation Oncology 2007 2:27

    Content type: Short report

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  36. Intensity-modulated radiation therapy (IMRT) affords unparalleled capacity to deliver conformal radiation doses to tumors in the central nervous system. However, to date, there are few reported outcomes from u...

    Authors: Clifton D Fuller, Mehee Choi, Britta Forthuber, Samuel J Wang, Nancy Rajagiriyil, Bill J Salter and Martin Fuss

    Citation: Radiation Oncology 2007 2:26

    Content type: Research

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  37. The ATM protein is activated as a result of ionizing radiation, and genetic variants of the ATM gene may therefore affect the level of radiation-induced damage. Individuals heterozygous for ATM mutations have bee...

    Authors: Hege Edvardsen, Toril Tefre, Laila Jansen, Phuong Vu, Bruce G Haffty, Sophie D Fosså, Vessela N Kristensen and Anne-Lise Børresen-Dale

    Citation: Radiation Oncology 2007 2:25

    Content type: Research

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  38. At Gesellschaft für Schwerionenforschung (GSI) more than 330 patients have been treated with scanned carbon ion beams in a pilot project. To date, only stationary tumors have been treated. In the presence of m...

    Authors: Christoph Bert and Eike Rietzel

    Citation: Radiation Oncology 2007 2:24

    Content type: Research

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  39. Several experimental strategies of radiation-induced central nervous system toxicity prevention have recently resulted in encouraging data. The present review summarizes the background for this research and th...

    Authors: Carsten Nieder, Nicolaus Andratschke and Sabrina T Astner

    Citation: Radiation Oncology 2007 2:23

    Content type: Review

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  40. Impact of non-pharmacological innovations on cancer cure rates is difficult to assess. It remains unclear, whether outcome improves with 2- [18-F]-fluoro-2-deoxyglucose-positron emission tomography and integra...

    Authors: Sacha Rothschild, Gabriela Studer, Burkhardt Seifert, Pia Huguenin, Christoph Glanzmann, J Bernard Davis, Urs M Lütolf, Thomas F Hany and I Frank Ciernik

    Citation: Radiation Oncology 2007 2:22

    Content type: Research

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  41. To determine the usefulness of dose volume histogram (DVH) factors for predicting the occurrence of radiation pneumonitis (RP) after application of stereotactic radiation therapy (SRT) for lung tumors, DVH fac...

    Authors: Hideomi Yamashita, Keiichi Nakagawa, Naoki Nakamura, Hiroki Koyanagi, Masao Tago, Hiroshi Igaki, Kenshiro Shiraishi, Nakashi Sasano and Kuni Ohtomo

    Citation: Radiation Oncology 2007 2:21

    Content type: Research

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