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  1. We have previously shown that small molecule PDGF receptor tyrosine kinase inhibitors (RTKI) can drastically attenuate radiation-induced pulmonary fibrosis if the drug administration starts at the time of radi...

    Authors: Minglun Li, Amir Abdollahi, Hermann-Josef Gröne, Kenneth E Lipson, Claus Belka and Peter E Huber

    Citation: Radiation Oncology 2009 4:66

    Content type: Research

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  2. We regret to report that a proofreading error caused an incorrect legend and description of the contents of table 6 to appear in our original publication of this work. The correct description of table 6 is: Un...

    Authors: Jarad M Martin, Andrew Bayley, Robert Bristow, Peter Chung, Mary Gospodarowicz, Cynthia Menard, Michael Milosevic, Tara Rosewall, Padraig R Warde and Charles N Catton

    Citation: Radiation Oncology 2009 4:65

    Content type: Erratum

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    The original article was published in Radiation Oncology 2009 4:50

  3. Boron neutron capture therapy (BNCT) is a selective radiotherapy, being effective for the treatment of even advanced malignancies in head and neck regions as well as brain tumors and skin melanomas. To clarify...

    Authors: Yusei Fujita, Itsuro Kato, Soichi Iwai, Koji Ono, Minoru Suzuki, Yoshinori Sakurai, Ken Ohnishi, Takeo Ohnishi and Yoshiaki Yura

    Citation: Radiation Oncology 2009 4:63

    Content type: Research

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  4. To review the experience and to evaluate the treatment plan of using helical tomotherapy (HT) for the treatment of cervical cancer.

    Authors: Chen-Hsi Hsieh, Ming-Chow Wei, Hsing-Yi Lee, Sheng-Mou Hsiao, Chien-An Chen, Li-Ying Wang, Yen-Ping Hsieh, Tung-Hu Tsai, Yu-Jen Chen and Pei-Wei Shueng

    Citation: Radiation Oncology 2009 4:62

    Content type: Research

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  5. In locally advanced rectal cancer, 5-Fluorouracil (5-FU)-based chemoradiation is the standard treatment. The main acute toxicity of this treatment is enteritis. Due to its potential radiosensitizing properties...

    Authors: Adalsteinn Gunnlaugsson, Per Nilsson, Elisabeth Kjellén and Anders Johnsson

    Citation: Radiation Oncology 2009 4:61

    Content type: Research

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  6. Primary orbital lymphoma is a rare disease that accounts for 10% of all orbital tumors. Radiotherapy on the orbital cavity is the treatment of choice for this unusual presentation of localized non-Hodgkin's ly...

    Authors: Luigi De Cicco, Laura Cella, Raffaele Liuzzi, Raffaele Solla, Antonio Farella, Giorgio Punzo, Fausto Tranfa, Diego Strianese, Manuel Conson, Giulio Bonavolontà, Marco Salvatore and Roberto Pacelli

    Citation: Radiation Oncology 2009 4:60

    Content type: Research

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  7. The underlying molecular and cellular mechanisms of radiation pneumonitis (RP) are very complex. Several biological factors need to be considered together with the well known dosimetric parameters for understa...

    Authors: Ji-Yoon Kim, Yeon-Sil Kim, Young-Kyoon Kim, Hyun-Jin Park, Seung-Joon Kim, Jin-Hyoung Kang, Young-Pil Wang, Hong-Seok Jang, Sang-Nam Lee and Sei-Chul Yoon

    Citation: Radiation Oncology 2009 4:59

    Content type: Research

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  8. Cervical cancer is treated mainly by surgery and radiotherapy. Toxicity due to radiation is a limiting factor for treatment success. Determination of lymphocyte radiosensitivity by radio-induced apoptosis aris...

    Authors: Elisa Bordón, Luis Alberto Henríquez Hernández, Pedro C Lara, Beatriz Pinar, Fausto Fontes, Carlos Rodríguez Gallego and Marta Lloret

    Citation: Radiation Oncology 2009 4:58

    Content type: Research

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  9. Biological brain tumor imaging using O-(2-[18F]fluoroethyl)-L-tyrosine (FET)-PET combined with inverse treatment planning for locally restricted dose escalation in patients with glioblastoma multiforme seems to b...

    Authors: Marc D Piroth, Michael Pinkawa, Richard Holy, Gabriele Stoffels, Cengiz Demirel, Charbel Attieh, Hans J Kaiser, Karl J Langen and Michael J Eble

    Citation: Radiation Oncology 2009 4:57

    Content type: Research

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  10. The observation that human meningioma cells strongly express somatostatin receptor (SSTR 2) was the rationale to analyze retrospectively in how far DOTATOC PET/CT is helpful to improve target volume delineatio...

    Authors: Barbara Gehler, Frank Paulsen, Mehmet Ö Öksüz, Till-Karsten Hauser, Susanne M Eschmann, Roland Bares, Christina Pfannenberg, Michael Bamberg, Peter Bartenstein, Claus Belka and Ute Ganswindt

    Citation: Radiation Oncology 2009 4:56

    Content type: Research

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  11. Reirradiation to the abdomen could potentially play a role in palliation of symptoms or local control in patients with gastrointestinal malignancies. Our goal was to retrospectively determine rates of toxicity...

    Authors: Waqar Haque, Christopher H Crane, Sunil Krishnan, Marc E Delclos, Milind Javle, Christopher R Garrett, Robert A Wolff and Prajnan Das

    Citation: Radiation Oncology 2009 4:55

    Content type: Short report

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  12. In the present work we compared the spatial uncertainties associated with a MR-based workflow for external radiotherapy of prostate cancer to a standard CT-based workflow. The MR-based workflow relies on targe...

    Authors: Tufve Nyholm, Morgan Nyberg, Magnus G Karlsson and Mikael Karlsson

    Citation: Radiation Oncology 2009 4:54

    Content type: Research

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  13. To evaluate the functionality of the auditory system in patients who underwent radiotherapy and chemotherapy treatment with cisplatin to treat head and neck tumors.

    Authors: Ana Helena B Dell'Aringa, Myrian L Isaac, Gustavo V Arruda, Maria Carolina BN Esteves, Alfredo Rafael Dell'Aringa, José Luis S Júnior and Alexandre F Rodrigues

    Citation: Radiation Oncology 2009 4:53

    Content type: Review

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  14. To investigate the association between dose to various anatomical structures and dysphagia among patients with head and neck cancer treated by definitive intensity-modulated radiotherapy (IMRT) and concurrent ...

    Authors: Baoqing Li, Dan Li, Derick H Lau, D Gregory Farwell, Quang Luu, David M Rocke, Kathleen Newman, Jean Courquin, James A Purdy and Allen M Chen

    Citation: Radiation Oncology 2009 4:52

    Content type: Research

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  15. Prostate radiotherapy (RT) dose escalation has been reported to result in improved biochemical control at the cost of greater late toxicity. We report on the application of 79.8 Gy in 42 fractions of prostate ...

    Authors: Jarad M Martin, Andrew Bayley, Robert Bristow, Peter Chung, Mary Gospodarowicz, Cynthia Menard, Michael Milosevic, Tara Rosewall, Padraig R Warde and Charles N Catton

    Citation: Radiation Oncology 2009 4:50

    Content type: Research

    Published on:

    The Erratum to this article has been published in Radiation Oncology 2009 4:65

  16. The combination of ionizing radiation with the pro-apoptotic TRAIL receptor antibody lexatumumab has been shown to exert considerable synergistic apoptotic effects in vitro and in short term growth delay assay...

    Authors: Patrizia Marini, Dorothea Junginger, Stefan Stickl, Wilfried Budach, Maximilian Niyazi and Claus Belka

    Citation: Radiation Oncology 2009 4:49

    Content type: Research

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  17. Radiotherapy (RT) volumes for anal cancer are large and of moderate complexity when organs at risk (OAR) such as testis, small bowel and bladder are at least partially to be shielded. Volumetric intensity modu...

    Authors: Florian Stieler, Dirk Wolff, Frank Lohr, Volker Steil, Yasser Abo-Madyan, Friedlieb Lorenz, Frederik Wenz and Sabine Mai

    Citation: Radiation Oncology 2009 4:48

    Content type: Research

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  18. Gossypol, a naturally occurring polyphenolic compound has been identified as a small molecule inhibitor of anti-apoptotic Bcl-2 family proteins. It induces apoptosis in a wide range of tumor cell lines and enh...

    Authors: Shuraila F Zerp, Rianne Stoter, Gitta Kuipers, Dajun Yang, Marc E Lippman, Wim J van Blitterswijk, Harry Bartelink, Rogier Rooswinkel, Vincent Lafleur and Marcel Verheij

    Citation: Radiation Oncology 2009 4:47

    Content type: Research

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  19. Alkylphosphocholines represent promising antineoplastic drugs that induce cell death in tumor cells by primary interaction with the cell membrane. Recently we could show that a combination of radiotherapy with...

    Authors: Guido Henke, Lars H Lindner, Michael Vogeser, Hans-Jörg Eibl, Jürgen Wörner, Arndt C Müller, Michael Bamberg, Kirsten Wachholz, Claus Belka and Verena Jendrossek

    Citation: Radiation Oncology 2009 4:46

    Content type: Research

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  20. High grade gliomas (HGG) are typically treated with a combination of surgery, radiotherapy and chemotherapy. Three dimensional (3D) conformal radiotherapy treatment planning is still the main stay of treatment...

    Authors: Leor Zach, Bronwyn Stall, Holly Ning, John Ondos, Barbara Arora, Shankavaram Uma, Robert W Miller, Deborah Citrin and Kevin Camphausen

    Citation: Radiation Oncology 2009 4:45

    Content type: Research

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  21. Meningiomas located in the region of the base of skull are difficult to access. Complex combined surgical approaches are more likely to achieve complete tumor removal, but frequently at a cost of treatment rel...

    Authors: Giuseppe Minniti, Maurizio Amichetti and Riccardo Maurizi Enrici

    Citation: Radiation Oncology 2009 4:42

    Content type: Review

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  22. Programmed cell death (PCD) is essential for development and homeostasis of multicellular organisms and can occur by caspase-dependent apoptosis or alternatively, by caspase-independent PCD (ciPCD). Bcl-2, a c...

    Authors: Andrea Deerberg, Justyna Sosna, Lutz Thon, Claus Belka and Dieter Adam

    Citation: Radiation Oncology 2009 4:41

    Content type: Research

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  23. The availability of alternative sources of information, e. g. the internet, may influence the quantity and quality of information cancer patients receive regarding their disease and treatment. The purpose of t...

    Authors: Johannes Adler, Yvonne Paelecke-Habermann, Patrick Jahn, Margarete Landenberger, Bernd Leplow and Dirk Vordermark

    Citation: Radiation Oncology 2009 4:40

    Content type: Research

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  24. Parameter optimization in the process of inverse treatment planning for intensity modulated radiation therapy (IMRT) is mainly conducted by human planners in order to create a plan with the desired dose distri...

    Authors: Florian Stieler, Hui Yan, Frank Lohr, Frederik Wenz and Fang-Fang Yin

    Citation: Radiation Oncology 2009 4:39

    Content type: Research

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  25. The purpose of this study was to determine the dosimetric effect of on-line position correction for bladder tumor irradiation and to find methods to predict and handle this effect.

    Authors: Dominique C van Rooijen, Jeroen B van de Kamer, René Pool, Maarten CCM Hulshof, Caro CE Koning and Arjan Bel

    Citation: Radiation Oncology 2009 4:38

    Content type: Research

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  26. While IMRT is widely used in treating complex oncological cases in adults, it is not commonly used in pediatric radiation oncology for a variety of reasons. This report evaluates our 9 year experience using st...

    Authors: Florian Sterzing, Eva M Stoiber, Simeon Nill, Harald Bauer, Peter Huber, Jürgen Debus and Marc W Münter

    Citation: Radiation Oncology 2009 4:37

    Content type: Methodology

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  27. The aim of the study was to evaluate self-assessed bowel toxicity after radiotherapy (RT) for prostate cancer. In contrast to rectal bleeding, information concerning irritative symptoms (rectal urgency, pain) ...

    Authors: Michael Pinkawa, Marc D Piroth, Karin Fischedick, Sandra Nussen, Jens Klotz, Richard Holy and Michael J Eble

    Citation: Radiation Oncology 2009 4:36

    Content type: Research

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  28. When combined with adequate tumoricidal doses, accurate target volume delineation remains to be the one of the most important predictive factors for radiotherapy (RT) success in locally advanced or medically i...

    Authors: Berrin Pehlivan, Erkan Topkan, Cem Onal, Gul Nihal Nursal, Oznur Yuksel, Yemliha Dolek, Melek Nur Yavuz and Ali Aydin Yavuz

    Citation: Radiation Oncology 2009 4:35

    Content type: Research

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  29. A study was performed comparing volumetric modulated arcs (RA) and intensity modulation (with photons, IMRT, or protons, IMPT) radiation therapy (RT) for patients with recurrent prostate cancer after RT.

    Authors: Damien C Weber, Hui Wang, Luca Cozzi, Giovanna Dipasquale, Haleem G Khan, Osman Ratib, Michel Rouzaud, Hansjoerg Vees, Habib Zaidi and Raymond Miralbell

    Citation: Radiation Oncology 2009 4:34

    Content type: Research

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  30. In head and neck cancer, bilateral neck irradiation is the standard approach for many tumor locations and stages. Increasing knowledge on the pattern of nodal invasion leads to more precise targeting and norma...

    Authors: Laura Cerezo, Margarita Martín, Mario López, Alicia Marín and Alberto Gómez

    Citation: Radiation Oncology 2009 4:33

    Content type: Research

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  31. To retrospectively evaluate the results after a regimen of surgery, IORT (intraoperative radiotherapy), and EBRT (external beam radiotherapy) for soft-tissue sarcomas

    Authors: Marcus Niewald, Jochen Fleckenstein, Norbert Licht, Caroline Bleuzen and Christian Ruebe

    Citation: Radiation Oncology 2009 4:32

    Content type: Research

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  32. The DNA double-strand break (DSB) is the primary lethal lesion after therapeutic radiation. Thus, the development of assays to detect and to quantitate these lesions could have broad preclinical and clinical i...

    Authors: Dane Avondoglio, Tamalee Scott, Whoon Jong Kil, Mary Sproull, Philip J Tofilon and Kevin Camphausen

    Citation: Radiation Oncology 2009 4:31

    Content type: Research

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  33. Oxygen molecule modulates tumour response to radiotherapy. Higher radiation doses are required under hypoxic conditions to induce cell death. Hypoxia may inhibit the non-homologous end-joining DNA repair throu...

    Authors: Pedro C Lara, Marta Lloret, Bernardino Clavo, Rosa M Apolinario, Luis Alberto Henríquez-Hernández, Elisa Bordón, Fausto Fontes and Agustín Rey

    Citation: Radiation Oncology 2009 4:29

    Content type: Short report

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  34. Conformal external radiotherapy aims to improve tumor control by boosting tumor dose, reducing morbidity and sparing healthy tissues. To meet this objective careful visualization of the tumor and adjacent area...

    Authors: Chiang J Tyng, Rubens Chojniak, Paula NV Pinto, Marcelle A Borba, Almir GV Bitencourt, Ricardo C Fogaroli, Douglas G Castro and Paulo E Novaes

    Citation: Radiation Oncology 2009 4:28

    Content type: Research

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  35. A study was performed comparing dosimetric characteristics of volumetric modulated arcs (RapidArc, RA) and fixed field intensity modulated therapy (IMRT) on patients with bilateral breast carcinoma.

    Authors: Giorgia Nicolini, Alessandro Clivio, Antonella Fogliata, Eugenio Vanetti and Luca Cozzi

    Citation: Radiation Oncology 2009 4:27

    Content type: Methodology

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  36. To evaluate the impact of external beam radiation therapy (XRT) on weekly ultrasound determined post-void residual (PVR) urine volumes in patients with prostate cancer.

    Authors: Peter F Orio III, Gregory S Merrick, Zachariah A Allen, Wayne M Butler, Kent E Wallner, Brian S Kurko and Robert W Galbreath

    Citation: Radiation Oncology 2009 4:26

    Content type: Research

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  37. DCQ (2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide), a synthetic quinoxaline 1,4-dioxide, enhances the cytotoxic effect of ionizing radiation (IR) in vivo and in vitro. We sought to clarify whether incre...

    Authors: Joelle Haykal, Fady Geara, Makhluf J Haddadin, Colin A Smith and Hala Gali-Muhtasib

    Citation: Radiation Oncology 2009 4:25

    Content type: Research

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  38. Despite broad advances in multimodal treatment of locally advanced breast cancer (LABC), 30 to 40% of patients develop loco-regional relapse. The aim of this study was to analyze in a retrospective manner the ...

    Authors: Alberto Alvarado-Miranda, Oscar Arrieta, Carlos Gamboa-Vignolle, David Saavedra-Perez, Rafael Morales-Barrera, Enrique Bargallo-Rocha, Juan Zinser-Sierra, Victor Perez-Sanchez, Teresa Ramirez-Ugalde and Fernando Lara-Medina

    Citation: Radiation Oncology 2009 4:24

    Content type: Research

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  39. Over-expression of cyclooxygenase-2 (COX-2) enzyme has been reported in nasopharyngeal carcinoma (NPC). However, the prognostic significance of this has yet to be conclusively determined. Thus, from our random...

    Authors: Susan Li Er Loong, Jacqueline Siok Gek Hwang, Hui Hua Li, Joseph Tien Seng Wee, Swee Peng Yap, Melvin Lee Kiang Chua, Kam Weng Fong and Terence Wee Kiat Tan

    Citation: Radiation Oncology 2009 4:23

    Content type: Research

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  40. To assess the impact of two multileaf collimator (MLC) systems (2.5 and 5 mm leaf widths) on three-dimensional conformal radiotherapy, intensity-modulated radiotherapy, and dynamic conformal arc techniques for...

    Authors: James A Tanyi, Paige A Summers, Charles L McCracken, Yiyi Chen, Li-Chung Ku and Martin Fuss

    Citation: Radiation Oncology 2009 4:22

    Content type: Research

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  41. survivors of non-Hodgkin's lymphoma (NHL) are well known to be at an increased risk of second malignancies. In this study, we evaluated the incidence and clinical features of head and neck cancer (HNC) occurri...

    Authors: Kazuma Toda, Hitoshi Shibuya, Keiji Hayashi and Fumio Ayukawa

    Citation: Radiation Oncology 2009 4:21

    Content type: Research

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  42. Extracranial metastases from brain meningiomas is a rare, but well-documented entity. Metastases occur mostly in the lungs, pleura and liver, but may also affect lymph nodes and bones. We report here on a pati...

    Authors: Mirna Abboud, George Haddad, Mireille Kattar, Ibrahim Aburiziq and Fady B Geara

    Citation: Radiation Oncology 2009 4:20

    Content type: Short report

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  43. To evaluate the dosimetric differences between Superposition/Convolution (SC) and Monte Carlo (MC) calculated dose distributions for simultaneous integrated boost (SIB) prostate cancer intensity modulated radi...

    Authors: Nesrin Dogan, Ivaylo Mihaylov, Yan Wu, Paul J Keall, Jeffrey V Siebers and Michael P Hagan

    Citation: Radiation Oncology 2009 4:18

    Content type: Research

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