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  1. This study explores whether meningioma expresses epidermal growth factor receptor (EGFR) and determines if there is a correlation between the WHO grade of this tumor and the degree of EGFR expression.

    Authors: A Gabriella Wernicke, Adam P Dicker, Michal Whiton, Jana Ivanidze, Terry Hyslop, Elizabeth H Hammond, Arie Perry, David W Andrews and Lawrence Kenyon

    Citation: Radiation Oncology 2010 5:46

    Content type: Short report

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  2. Thoracic cancer treatment presents dosimetric difficulties due to respiratory motion and lung inhomogeneity. Monte Carlo and deformable image registration techniques have been proposed to be used in four-dimen...

    Authors: Tzung-Chi Huang, Ji-An Liang, Thomas Dilling, Tung-Hsin Wu and Geoffrey Zhang

    Citation: Radiation Oncology 2010 5:45

    Content type: Research

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  3. To assess radiobiological restrictions and tolerance doses as well as other toxic effects derived from repeated applications of single-fraction high dose rate irradiation of small liver volumes in clinical pra...

    Authors: Ricarda Rühl, Lutz Lüdemann, Anna Czarnecka, Florian Streitparth, Max Seidensticker, Konrad Mohnike, Maciej Pech, Peter Wust and Jens Ricke

    Citation: Radiation Oncology 2010 5:44

    Content type: Research

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  4. The aim of this study was to assess the results of curative surgery with and without radiotherapy in patients with T1-2N0-1 oral tongue squamous cell carcinoma (OSCC) and to evaluate survival and prognostic facto...

    Authors: Su Jung Shim, Jihye Cha, Woong Sub Koom, Gwi Eon Kim, Chang Geol Lee, Eun Chang Choi and Ki Chang Keum

    Citation: Radiation Oncology 2010 5:43

    Content type: Research

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  5. To compare the differences in dose-volume data among coplanar intensity modulated radiotherapy (IMRT), noncoplanar IMRT, and helical tomotherapy (HT) among patients with hepatocellular carcinoma (HCC) and port...

    Authors: Chen-Hsi Hsieh, Chia-Yuan Liu, Pei-Wei Shueng, Ngot-Swan Chong, Chih-Jen Chen, Ming-Jen Chen, Ching-Chung Lin, Tsang-En Wang, Shee-Chan Lin, Hung-Chi Tai, Hui-Ju Tien, Kuo-Hsin Chen, Li-Ying Wang, Yen-Ping Hsieh, David YC Huang and Yu-Jen Chen

    Citation: Radiation Oncology 2010 5:40

    Content type: Research

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  6. Concurrent platinum-based radiochemotherapy has been recommended as a standard of care in patients with locally advanced squamous cell head and neck carcinomas. Unfortunately, there is a lack of level one evid...

    Authors: Valentina Krstevska, Igor Stojkovski and Dusko Lukarski

    Citation: Radiation Oncology 2010 5:39

    Content type: Research

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  7. To analyze the rate of larynx preservation in patients of locally advanced hypopharyngeal cancer treated with intensity modulated radiotherapy (IMRT) plus concurrent chemotherapy, and compare the results with ...

    Authors: Wen-Yen Huang, Yee-Min Jen, Chang-Ming Chen, Yu-Fu Su, Chun-Shu Lin, Yaoh-Shiang Lin, Ying-Nan Chang, Hsing-Lung Chao, Kuen-Tze Lin and Li-Ping Chang

    Citation: Radiation Oncology 2010 5:37

    Content type: Research

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  8. To evaluate the association between the clinical, dosimetric factors and severe acute radiation pneumonitis (SARP) in patients with locally advanced non-small cell lung cancer (LANSCLC) treated with concurrent...

    Authors: Anhui Shi, Guangying Zhu, Hao Wu, Rong Yu, Fuhai Li and Bo Xu

    Citation: Radiation Oncology 2010 5:35

    Content type: Research

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  9. Fullerene compounds are known to possess antioxidant properties, a common property of chemical radioprotectors. DF-1 is a dendrofullerene nanoparticle with antioxidant properties previously found to be radiopr...

    Authors: Aaron P Brown, Eun Joo Chung, Mary Ellen Urick, William P Shield III, Anastasia L Sowers, Angela Thetford, Uma T Shankavaram, James B Mitchell and Deborah E Citrin

    Citation: Radiation Oncology 2010 5:34

    Content type: Research

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  10. This paper analyses normal tissue sparing capability of radiation treatment techniques in Hodgkin's lymphoma with large treatment volume.

    Authors: Laura Cella, Raffaele Liuzzi, Mario Magliulo, Manuel Conson, Luigi Camera, Marco Salvatore and Roberto Pacelli

    Citation: Radiation Oncology 2010 5:33

    Content type: Research

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  11. To determine the risk factors of severe radiation pneumonitis (RP) after stereotactic body radiation therapy (SBRT) for primary or secondary lung tumors.

    Authors: Hideomi Yamashita, Shino Kobayashi-Shibata, Atsuro Terahara, Kae Okuma, Akihiro Haga, Reiko Wakui, Kuni Ohtomo and Keiichi Nakagawa

    Citation: Radiation Oncology 2010 5:32

    Content type: Research

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  12. Radiation-induced diarrhea is frequently observed during pelvic radiotherapy. This study was performed to determine the ability of a probiotic containing live lactobacillus acidophilus plus bifidobacterium bif...

    Authors: Imjai Chitapanarux, Taned Chitapanarux, Patrinee Traisathit, Sudkaneung Kudumpee, Ekkasit Tharavichitkul and Vicharn Lorvidhaya

    Citation: Radiation Oncology 2010 5:31

    Content type: Research

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  13. A better understanding of the underlying mechanisms of DNA repair after low- and high-LET radiations represents a research priority aimed at improving the outcome of clinical radiotherapy. To date however, our...

    Authors: Veerle Vandersickel, Monica Mancini, Jacobus Slabbert, Emanuela Marras, Hubert Thierens, Gianpaolo Perletti and Anne Vral

    Citation: Radiation Oncology 2010 5:30

    Content type: Research

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  14. Radiation therapy is an important cancer treatment modality in both adjuvant and definitive setting, however, the use of radiation therapy for elective treatment of regional lymph nodes is controversial for pa...

    Authors: Wenjie Sun, Cheng N Leong, Zhen Zhang and Jiade J Lu

    Citation: Radiation Oncology 2010 5:28

    Content type: Research

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  15. To answer the question if and to which extent acute symptoms at the end and/or several weeks after radiotherapy can predict adverse urinary and gastrointestinal long-term quality of life (QoL).

    Authors: Michael Pinkawa, Richard Holy, Marc D Piroth, Karin Fischedick, Sandra Schaar, Dalma Székely-Orbán and Michael J Eble

    Citation: Radiation Oncology 2010 5:27

    Content type: Research

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  16. Radiation pneumonia and subsequent radiation lung fibrosis are major dose-limiting complications for patients undergoing thoracic radiotherapy. Interleukin-6 (IL-6) is a pleiotropic cytokine and plays importan...

    Authors: Toshiyuki Ogata, Hideya Yamazaki, Teruki Teshima, Ayaka Kihara, Yuko Suzumoto, Takehiro Inoue, Norihiro Nishimoto and Nariaki Matsuura

    Citation: Radiation Oncology 2010 5:26

    Content type: Research

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  17. Endothelial cells (EC) in tumor and normal tissue constitute critical radiotherapy targets. MicroRNAs have emerged as master switchers of the cellular transcriptome. Here, we seek to investigate the role of mi...

    Authors: Mechthild Wagner-Ecker, Christian Schwager, Ute Wirkner, Amir Abdollahi and Peter E Huber

    Citation: Radiation Oncology 2010 5:25

    Content type: Research

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  18. Micrometastases of colorectal liver metastases are present in up to 50% of lesions. In this study we sought to determine the threshold dose for local control of occult micrometastases in patients undergoing CT...

    Authors: Max Seidensticker, Peter Wust, Ricarda Rühl, Konrad Mohnike, Maciej Pech, Gero Wieners, Günther Gademann and Jens Ricke

    Citation: Radiation Oncology 2010 5:24

    Content type: Research

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  19. Mucositis is a toxic side effect of anti-cancer treatments and is a major focus in cancer research. Pro-inflammatory cytokines have previously been implicated in the pathophysiology of chemotherapy-induced gas...

    Authors: Zhi Yi Ong, Rachel J Gibson, Joanne M Bowen, Andrea M Stringer, Jocelyn M Darby, Richard M Logan, Ann SJ Yeoh and Dorothy M Keefe

    Citation: Radiation Oncology 2010 5:22

    Content type: Research

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  20. To determine the variation in target delineation of nasopharyngeal carcinoma and the impact of measures to minimize this variation.

    Authors: Coen RN Rasch, Roel JHM Steenbakkers, Isabelle Fitton, Joop C Duppen, Peter JCM Nowak, Frank A Pameijer, Avraham Eisbruch, Johannes HAM Kaanders, Frank Paulsen and Marcel van Herk

    Citation: Radiation Oncology 2010 5:21

    Content type: Research

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  21. Current staging systems have limited ability to adjust optimal therapy in advanced nasopharyngeal carcinoma (NPC). This study aimed to delineate the correlation between tumor volume, treatment outcome and chem...

    Authors: Ching-Chih Lee, Tze-Ta Huang, Moon-Sing Lee, Shih-Hsuan Hsiao, Hon-Yi Lin, Yu-Chieh Su, Feng-Chun Hsu and Shih-Kai Hung

    Citation: Radiation Oncology 2010 5:20

    Content type: Research

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  22. To study the set-up errors, PTV margin and toxicity of cone beam CT (CBCT) guided hypofractionated radiotherapy with active breathing control (ABC) for patients with non-small cell lung cancer (NSCLC) or metas...

    Authors: Yali Shen, Hong Zhang, Jin Wang, Renming Zhong, Xiaoqing Jiang, Qinfeng Xu, Xin Wang, Sen Bai and Feng Xu

    Citation: Radiation Oncology 2010 5:19

    Content type: Research

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  23. Giant cell tumors are rare neoplasms, representing less than 5% of all bone tumors. The vast majority of giant cell tumors occurs in extremity sites and is treated by surgery alone. However, a small percentage...

    Authors: Falk Roeder, Carmen Timke, Felix Zwicker, Christian Thieke, Marc Bischof, Jürgen Debus and Peter E Huber

    Citation: Radiation Oncology 2010 5:18

    Content type: Research

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  24. To compare target dose distribution, comformality, normal tissue avoidance, and irradiated body volume (IBV) in 3DCRT using classic anatomical landmarks (c3DCRT), 3DCRT fitting the PTV (f3DCRT), and intensity-...

    Authors: Leire Arbea, Luis Isaac Ramos, Rafael Martínez-Monge, Marta Moreno and Javier Aristu

    Citation: Radiation Oncology 2010 5:17

    Content type: Methodology

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  25. The purpose of this pilot study was to detect a correlation between serum cytokine levels and severity of mucositis, necessitating installation of a percutaneous endoscopic gastrostomy tube (PEG) in head and n...

    Authors: Amichay Meirovitz, Michal Kuten, Salem Billan, Roxolyana Abdah-Bortnyak, Anat Sharon, Tamar Peretz, Mordechai Sela, Moshe Schaffer and Vivian Barak

    Citation: Radiation Oncology 2010 5:16

    Content type: Research

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  26. In recent years data from both mouse models and human tumors suggest that loss of one allele of genes involved in DNA repair pathways may play a central role in genomic instability and carcinogenesis. Addition...

    Authors: Fengtao Su, Lubomir B Smilenov, Thomas Ludwig, Libin Zhou, Jiayun Zhu, Guangming Zhou and Eric J Hall

    Citation: Radiation Oncology 2010 5:15

    Content type: Research

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  27. To report about initial technical and clinical experience in preoperative radiation treatment of rectal cancer with volumetric modulated arcs with the RapidArc® (RA) technology.

    Authors: Antonella Richetti, Antonella Fogliata, Alessandro Clivio, Giorgia Nicolini, Gianfranco Pesce, Emanuela Salati, Eugenio Vanetti and Luca Cozzi

    Citation: Radiation Oncology 2010 5:14

    Content type: Research

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  28. To determine the outcome of patients with brain metastasis (BM) from lung cancer treated with an external beam radiotherapy boost (RTB) after whole brain radiotherapy (WBRT).

    Authors: Nathalie Casanova, Zohra Mazouni, Sabine Bieri, Christophe Combescure, Alessia Pica and Damien C Weber

    Citation: Radiation Oncology 2010 5:13

    Content type: Research

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  29. Three-dimensional conformal radiation therapy (3DCRT)/intensity-modulated radiation therapy (IMRT) combined with or without transcatheter arterial chemoembolization (TACE) for locally advanced hepatocellular c...

    Authors: Jian-Dong Zhao, Jin Liu, Zhi-Gang Ren, Ke Gu, Zhen-Hua Zhou, Wen-Tao Li, Zhen Chen, Zhi-Yong Xu, Lu-Ming Liu and Guo-Liang Jiang

    Citation: Radiation Oncology 2010 5:12

    Content type: Study protocol

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  30. Instable and painful vertebral metastases in patients with progressive visceral metastases present a common therapeutic dilemma. We developed a novel approach to deliver intraoperative radiotherapy (IORT) duri...

    Authors: Frederik Wenz, Frank Schneider, Christian Neumaier, Uta Kraus-Tiefenbacher, Tina Reis, René Schmidt and Udo Obertacke

    Citation: Radiation Oncology 2010 5:11

    Content type: Methodology

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  31. FDG-PET/CT imaging has an emerging role in staging and treatment planning of various tumor locations and a number of literature studies show that also the carcinoma of the anal canal may benefit from this diag...

    Authors: Marco Krengli, Maria E Milia, Lucia Turri, Eleonora Mones, Maria C Bassi, Barbara Cannillo, Letizia Deantonio, Gianmauro Sacchetti, Marco Brambilla and Eugenio Inglese

    Citation: Radiation Oncology 2010 5:10

    Content type: Research

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  32. A fourteen years-old boy was treated post-operatively with proton therapy for a recurrent low-grade oligodendroglioma located in the tectal region. Six months after the end of irradiation (RT), a new enhancing...

    Authors: Candice Meyzer, Frédéric Dhermain, Denis Ducreux, Jean-Louis Habrand, Pascale Varlet, Christian Sainte-Rose, Christelle Dufour and Jacques Grill

    Citation: Radiation Oncology 2010 5:9

    Content type: Case report

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  33. The histamine receptor-1 (H1)-antagonist, loratadine has been shown to inhibit growth of human colon cancer xenografts in part due to cell cycle arrest in G2/M. Since this is a radiation sensitive phase of the...

    Authors: Benjamin P Soule, Nicole L Simone, William G DeGraff, Rajani Choudhuri, John A Cook and James B Mitchell

    Citation: Radiation Oncology 2010 5:8

    Content type: Research

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  34. Castleman disease (CD) is a rare benign disorder characterised by hyperplasia of lymphoid tissue that may develop at a single site or throughout the body. The etiology of this disorder is unclear, although the...

    Authors: Iris AC de Vries, Marjolein MS van Acht, Thomas BJ Demeyere, Marnix LM Lybeert, Jean-Paul de Zoete and Grard AP Nieuwenhuijzen

    Citation: Radiation Oncology 2010 5:7

    Content type: Case report

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  35. Sublethal doses of whole brain irradiation (WBI) are commonly administered therapeutically and frequently result in late delayed radiation injuries, manifesting as severe and irreversible cognitive impairment....

    Authors: Kenneth A Jenrow, Stephen L Brown, Jianguo Liu, Andrew Kolozsvary, Karen Lapanowski and Jae Ho Kim

    Citation: Radiation Oncology 2010 5:6

    Content type: Research

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  36. FLAIR and T2 weighted MRIs are used based on institutional preference to delineate high grade gliomas and surrounding edema for radiation treatment planning. Although these sequences have inherent physical dif...

    Authors: Bronwyn Stall, Leor Zach, Holly Ning, John Ondos, Barbara Arora, Uma Shankavaram, Robert W Miller, Deborah Citrin and Kevin Camphausen

    Citation: Radiation Oncology 2010 5:5

    Content type: Research

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  37. Head and neck cancer is treated mainly by surgery and radiotherapy. Normal tissue toxicity due to x-ray exposure is a limiting factor for treatment success. Many efforts have been employed to develop predictiv...

    Authors: Elisa Bordón, Luis Alberto Henríquez-Hernández, Pedro C Lara, Ana Ruíz, Beatriz Pinar, Carlos Rodríguez-Gallego and Marta Lloret

    Citation: Radiation Oncology 2010 5:4

    Content type: Short report

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  38. To assess the accuracy of fractionated stereotactic radiotherapy (FSRT) using a stereotactic mask fixation system.

    Authors: Giuseppe Minniti, Maurizio Valeriani, Enrico Clarke, Marco D'Arienzo, Michelangelo Ciotti, Roberto Montagnoli, Francesca Saporetti and Riccardo Maurizi Enrici

    Citation: Radiation Oncology 2010 5:1

    Content type: Methodology

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  39. The spine is the most common site for bone metastases. Radiation therapy is a common treatment for palliation of pain and for prevention or treatment of spinal cord compression. Helical tomotherapy (HT), a new...

    Authors: Pei-Wei Shueng, Shih-Chiang Lin, Hou-Tai Chang, Ngot-Swan Chong, Yu-Jen Chen, Li-Ying Wang, Yen-Ping Hsieh and Chen-Hsi Hsieh

    Citation: Radiation Oncology 2009 4:71

    Content type: Case report

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  40. Accurate localisation of the lumpectomy cavity (LC) volume is one of the most critical points in 3D-conformal Partial breast irradiation (3D-APBI) treatment planning because the irradiated volume is restricted...

    Authors: Maia Dzhugashvili, Elodie Tournay, Charlotte Pichenot, Ariane Dunant, Eduardo Pessoa, Adel Khallel, Sébastien Gouy, Catherine Uzan, Jean-Rémy Garbay, Françoise Rimareix, Marc Spielmann, Philippe Vielh, Hugo Marsiglia and Céline Bourgier

    Citation: Radiation Oncology 2009 4:70

    Content type: Research

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  41. Glioblastoma multiforme (GBM) is resistant to current cytotoxic therapies, in part because of enhanced DNA repair. Activation of the receptor tyrosine kinase c-Met has been shown to protect cancer cells from D...

    Authors: James W Welsh, Daruka Mahadevan, Ron Ellsworth, Laurence Cooke, David Bearss and Baldassarre Stea

    Citation: Radiation Oncology 2009 4:69

    Content type: Research

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  42. To evaluate clinical outcome after preoperative short-course radiotherapy for rectal cancer with twice daily fractions of 2.9 Gy to a total dose of 29 Gy and adjuvant chemotherapy for pathological stage UICC ≥...

    Authors: Matthias Guckenberger, Joern Wulf, Andreas Thalheimer, Daniel Wehner, Arnulf Thiede, Gottfried Müller, Marco Sailer and Michael Flentje

    Citation: Radiation Oncology 2009 4:67

    Content type: Research

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