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  1. To determine the optimal approach to delineating patient-specific internal gross target volumes (IGTV) from four-dimensional (4-D) computed tomography (CT) image data sets used in the planning of radiation tre...

    Authors: Muthuveni Ezhil, Sastry Vedam, Peter Balter, Bum Choi, Dragan Mirkovic, George Starkschall and Joe Y Chang

    Citation: Radiation Oncology 2009 4:4

    Content type: Research

    Published on:

  2. This study evaluated the dosimetric impact of various treatment techniques as well as collimator leaf width (2.5 vs 5 mm) for three groups of tumors – spine tumors, brain tumors abutting the brainstem, and liv...

    Authors: Q Jackie Wu, Zhiheng Wang, John P Kirkpatrick, Zheng Chang, Jeffrey J Meyer, Mei Lu, Calvin Huntzinger and Fang-Fang Yin

    Citation: Radiation Oncology 2009 4:3

    Content type: Research

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  3. A phase III multi-centre randomised trial (ROSEL) has been initiated to establish the role of stereotactic radiotherapy in patients with operable stage IA lung cancer. Due to rapid changes in radiotherapy tech...

    Authors: Coen W Hurkmans, Johan P Cuijpers, Frank J Lagerwaard, Joachim Widder, Uulke A van der Heide, Danny Schuring and Suresh Senan

    Citation: Radiation Oncology 2009 4:1

    Content type: Study protocol

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  4. To compare morphological gross tumor volumes (GTVs), defined as pre- and postoperative gadolinium enhancement on T1-weighted magnetic resonance imaging to biological tumor volumes (BTVs), defined by the uptake of...

    Authors: Damien C Weber, Thomas Zilli, Franz Buchegger, Nathalie Casanova, Guy Haller, Michel Rouzaud, Philippe Nouet, Giovanna Dipasquale, Osman Ratib, Habib Zaidi, Hansjorg Vees and Raymond Miralbell

    Citation: Radiation Oncology 2008 3:44

    Content type: Research

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  5. Radiation therapy is generally contraindicated for cancer patients with collagen vascular diseases (CVD) such as scleroderma due to an increased risk of fibrosis. The tight skin (TSK) mouse has skin which, in ...

    Authors: Sanath Kumar, Andrew Kolozsvary, Robert Kohl, Mei Lu, Stephen Brown and Jae Ho Kim

    Citation: Radiation Oncology 2008 3:40

    Content type: Research

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  6. To assess the radiation dose delivered to the heart and ipsilateral lung during accelerated partial breast brachytherapy using a MammoSite™ applicator and compare to those produced by whole breast external bea...

    Authors: Alexandra J Stewart, Desmond A O'Farrell, Robert A Cormack, Jorgen L Hansen, Atif J Khan, Subhakar Mutyala and Phillip M Devlin

    Citation: Radiation Oncology 2008 3:39

    Content type: Research

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  7. Image-guidance systems allow accurate interfractional repositioning of IMRT treatments, however, these may require up to 15 minutes. Therefore intrafraction motion might have an impact on treatment precision. ...

    Authors: Judit Boda-Heggemann, Frederick Marc Köhler, Hansjörg Wertz, Michael Ehmann, Brigitte Hermann, Nadja Riesenacker, Beate Küpper, Frank Lohr and Frederik Wenz

    Citation: Radiation Oncology 2008 3:37

    Content type: Research

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  8. To report acute and late toxicity in prostate cancer patients treated by dose escalated intensity-modulated radiation therapy (IMRT) and organ tracking.

    Authors: Pirus Ghadjar, Jacqueline Vock, Daniel Vetterli, Peter Manser, Roland Bigler, Jan Tille, Axel Madlung, Frank Behrensmeier, Roberto Mini and Daniel M Aebersold

    Citation: Radiation Oncology 2008 3:35

    Content type: Research

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  9. Intrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target motion by tracking with the treatment b...

    Authors: Sven Oliver Grözinger, Christoph Bert, Thomas Haberer, Gerhard Kraft and Eike Rietzel

    Citation: Radiation Oncology 2008 3:34

    Content type: Research

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  10. Nestin is an intermediate filament protein that has been implicated in early stages of neuronal lineage commitment. Based on the heterogeneous expression of nestin in GBM and its potential to serve as a marker...

    Authors: Prakash Chinnaiyan, Meihua Wang, Amyn M Rojiani, Philip J Tofilon, Arnab Chakravarti, K Kian Ang, Hua-Zhong Zhang, Elizabeth Hammond, Walter Curran Jr and Minesh P Mehta

    Citation: Radiation Oncology 2008 3:32

    Content type: Research

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  11. Intensity modulated radiotherapy (IMRT) using sliding window technique utilises a leaf sequencing algorithm, which takes some control system limitations like dose rates (DR) and velocity of the leafs (LV) into...

    Authors: Hilke Vorwerk, Daniela Wagner and Clemens F Hess

    Citation: Radiation Oncology 2008 3:31

    Content type: Research

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  12. The primary objective of this study was to determine the maximum tolerated dose (MTD) of escalating doses of radiotherapy (RT) concomitantly with a fixed dose of gemcitabine (300 mg/m2/week) within the same overa...

    Authors: Tom Budiharto, Karin Haustermans, Eric Van Cutsem, Werner Van Steenbergen, Baki Topal, Raymond Aerts, Nadine Ectors, Didier Bielen, Dirk Vanbeckevoort, Laurence Goethals and Chris Verslype

    Citation: Radiation Oncology 2008 3:30

    Content type: Research

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  13. Positron emission tomography (PET) has a potential improvement for staging and radiation treatment planning of various tumor sites. We analyzed the use of 18F-fluorodeoxyglucose (FDG)-PET/computed tomography (CT)...

    Authors: Letizia Deantonio, Debora Beldì, Giuseppina Gambaro, Gianfranco Loi, Marco Brambilla, Eugenio Inglese and Marco Krengli

    Citation: Radiation Oncology 2008 3:29

    Content type: Study protocol

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  14. Treatment options for loco-regional recurrent breast cancer after previous irradiation are limited. The efficacy of chemotherapy might be hampered because of impaired tissue perfusion in preirradiated tissue. ...

    Authors: Florian Würschmidt, Jörg Dahle, Cordula Petersen, Claudia Wenzel, Matthias Kretschmer and Christoph Bastian

    Citation: Radiation Oncology 2008 3:28

    Content type: Research

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  15. A lot of retrospective data concerning the effect of radiotherapy on the painful heel spur (plantar fasciitis) is available in the literature. Nevertheless, a randomized proof of this effect is still missing. ...

    Authors: Marcus Niewald, M Heinrich Seegenschmiedt, Oliver Micke and Stefan Gräber

    Citation: Radiation Oncology 2008 3:27

    Content type: Study protocol

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  16. Radiation medicine has previously utilized planning methods based primarily on anatomic and volumetric imaging technologies such as CT (Computerized Tomography), ultrasound, and MRI (Magnetic Resonance Imaging...

    Authors: Nidhi Sharma, Donald Neumann and Roger Macklis

    Citation: Radiation Oncology 2008 3:25

    Content type: Review

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  17. To expand and test the dosimetric procedure, known as GLAaS, for amorphous silicon detectors to the RapidArc intensity modulated arc delivery with Varian infrastructures and to test the RapidArc dosimetric rel...

    Authors: Giorgia Nicolini, Eugenio Vanetti, Alessandro Clivio, Antonella Fogliata, Stine Korreman, Jiri Bocanek and Luca Cozzi

    Citation: Radiation Oncology 2008 3:24

    Content type: Methodology

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  18. To use amifostine concurrently with radiochemotherapy (CT-RT) or radiotherapy (RT) alone in order to prevent dry eye syndrome in patients with malignancies located in the fronto-orbital region.

    Authors: David Goldblum, Pirus Ghadjar, Juergen Curschmann, Richard Greiner and Daniel Aebersold

    Citation: Radiation Oncology 2008 3:22

    Content type: Research

    Published on:

  19. Prostate cancer is the leading form of cancer diagnosed among North American men. Most patients present with localized disease, which can be effectively treated with a variety of different modalities. These ar...

    Authors: Kurian Jones Joseph, Riaz Alvi, David Skarsgard, Jon Tonita, Nadeem Pervez, Cormac Small and Patricia Tai

    Citation: Radiation Oncology 2008 3:20

    Content type: Research

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  20. As the majority of prostate cancers (PC) express estrogen receptors, we evaluated the combination of radiation and estrogenic stimulation (estrogen and genistein) on the radiosensitivity of PC cells in vitro.

    Authors: Robert Michael Hermann, Hendrik Andreas Wolff, Hubertus Jarry, Paul Thelen, Carsten Gruendker, Margret Rave-Fraenk, Heinz Schmidberger and Hans Christiansen

    Citation: Radiation Oncology 2008 3:19

    Content type: Research

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  21. Radiotherapy (RT) has become an important treatment modality in pediatric oncology, but its delivery to young children with cancer is challenging and general anesthesia is often needed.

    Authors: Sonja Haeberli, Michael A Grotzer, Felix K Niggli, Markus A Landolt, Claudia Linsenmeier, Roland A Ammann and Nicole Bodmer

    Citation: Radiation Oncology 2008 3:17

    Content type: Research

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  22. Hypofractionated radiotherapy has been used for the treatment of AVMs and brain metastases. Hypofractionation necessitates the use of a relocatable stereotactic frame that has to be applied on several occasion...

    Authors: Peter Lindvall, Per Bergström, Per-Olov Löfroth, Roger Henriksson and A Tommy Bergenheim

    Citation: Radiation Oncology 2008 3:16

    Content type: Research

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  23. We evaluated the acute and late toxicity after high-dose intensity-modulated radiotherapy (IMRT) with fiducial marker-based position verification for prostate cancer. Between 2001 and 2004, 331 patients with p...

    Authors: Irene M Lips, Homan Dehnad, Carla H van Gils, Arto E Boeken Kruger, Uulke A van der Heide and Marco van Vulpen

    Citation: Radiation Oncology 2008 3:15

    Content type: Short report

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  24. The shape of the dose-response curve at low doses differs from the linear quadratic model. The effect of a radio-adaptive response is the centre of many studies and well known inspite that the clinical applica...

    Authors: Silke B Schwarz, Pamela M Schaffer, Ulrike Kulka, Birgit Ertl-Wagner, Roswitha Hell and Moshe Schaffer

    Citation: Radiation Oncology 2008 3:12

    Content type: Research

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  25. Late effects after radiotherapy in childhood and adolescence have mainly been characterized retrospectively with small patient numbers. However, these analyses are limited due to little information regarding o...

    Authors: Tobias Bolling, Andreas Schuck, Hildegard Pape, Christian Rube, Barbara Pollinger, Beate Timmermann, Rolf D Kortmann, Karin Dieckmann and Normann Willich

    Citation: Radiation Oncology 2008 3:10

    Content type: Study protocol

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  26. To report our experience treating soft tissue sarcoma (STS) with high dose rate brachytherapy alone (HBRT) or in combination with external beam radiotherapy (EBRT) in pediatric patients.

    Authors: Gustavo A Viani, Paulo E Novaes, Alexandre A Jacinto, Celia B Antonelli, Antonio Cassio A Pellizzon, Elisa Y Saito and João V Salvajoli

    Citation: Radiation Oncology 2008 3:9

    Content type: Research

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  27. To assess whether an expanded (five level) risk stratification system can be used to identify the sub-group of intermediate risk patients with prostate cancer who benefit from combining androgen deprivation th...

    Authors: Matthew Beasley, Scott G Williams and Tom Pickles

    Citation: Radiation Oncology 2008 3:8

    Content type: Research

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  28. The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes. The purpose of this st...

    Authors: Hans Paul van der Laan, Wil V Dolsma, John H Maduro, Erik W Korevaar and Johannes A Langendijk

    Citation: Radiation Oncology 2008 3:6

    Content type: Research

    Published on:

  29. The aim of this treatment planning study was to investigate the potential advantages of intensity-modulated (IM) proton therapy (IMPT) compared with IM photon therapy (IMRT) in nasopharyngeal carcinoma (NPC).

    Authors: Zahra Taheri-Kadkhoda, Thomas Björk-Eriksson, Simeon Nill, Jan J Wilkens, Uwe Oelfke, Karl-Axel Johansson, Peter E Huber and Marc W Münter

    Citation: Radiation Oncology 2008 3:4

    Content type: Research

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  30. To evaluate the risk of rectal, bladder and small bowel toxicity in intensity modulated radiation therapy (IMRT) of the prostate only compared to additional irradiation of the pelvic lymphatic region.

    Authors: Matthias Guckenberger, Kurt Baier, Anne Richter, Dirk Vordermark and Michael Flentje

    Citation: Radiation Oncology 2008 3:3

    Content type: Research

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  31. Androgen suppression treatment (AST) might increase the risk of cardiac morbidity in prostate cancer patients. Possible explanations were provided, however, they disregard the potential contribution of prophyl...

    Authors: Carsten Nieder, Adam Pawinski, Nicolaus H Andratschke and Michael Molls

    Citation: Radiation Oncology 2008 3:2

    Content type: Research

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  32. To compare two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the setting of hypofractionated high-risk prostate cancer treatment.

    Authors: Jasper Yuen, George Rodrigues, Kristina Trenka, Terry Coad, Slav Yartsev, David D'Souza, Michael Lock and Glenn Bauman

    Citation: Radiation Oncology 2008 3:1

    Content type: Research

    Published on:

  33. Radiation dermatitis is a common side effect of radiation therapy (RT). In severe cases, RT must be interrupted until the skin heals, which can compromise treatment. The purpose of the study was to compare an ...

    Authors: Thomas E Merchant, Christina Bosley, Julie Smith, Pam Baratti, David Pritchard, Tina Davis, Chenghong Li and Xiaoping Xiong

    Citation: Radiation Oncology 2007 2:45

    Content type: Research

    Published on:

  34. Set-up errors are an inherent part of radiation treatment process. Coverage of target volume is a direct function of set-up margins, which should be optimized to prevent inadvertent irradiation of adjacent nor...

    Authors: Tejpal Gupta, Supriya Chopra, Avinash Kadam, Jai Prakash Agarwal, P Reena Devi, Sarbani Ghosh-Laskar and Ketayun Ardeshir Dinshaw

    Citation: Radiation Oncology 2007 2:44

    Content type: Short report

    Published on:

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