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  1. To investigate added morbidity associated with the addition of pelvic elective nodal irradiation (ENI) to hypofractionated radiotherapy to the prostate.

    Authors: Andrew M McDonald, Christopher B Baker, Richard A Popple, Kiran Shekar, Eddy S Yang, Rojymon Jacob, Rex Cardan, Robert Y Kim and John B Fiveash
    Citation: Radiation Oncology 2014 9:129
    Content type: Research Published on:

  2. To assess the feasibility and benefit of integrating four-dimensional (4D) Positron Emission Tomography (PET) – computed tomography (CT) for liver stereotactic body radiation therapy (SBRT) planning.

    Authors: Olivier Riou, Benjamin Serrano, David Azria, Benoit Paulmier, Remy Villeneuve, Pascal Fenoglietto, Antonella Artenie, Cécile Ortholan, Marc Faraggi and Juliette Thariat
    Citation: Radiation Oncology 2014 9:127
    Content type: Research Published on:

  3. The study evaluates frequency of and indications for disease-related radiotherapy in the palliative breast cancer (BC) situation and analyzes in which phase of the palliative disease course radiotherapy was ap...

    Authors: Kirsten Steinauer, Markus Wolfram Gross, Dorothy Jane Huang, Serenella Eppenberger-Castori and Uwe Güth
    Citation: Radiation Oncology 2014 9:126
    Content type: Research Published on:

  4. To establish guidelines for the selenium supplementation in radiotherapy we assessed the benefits and risks of selenium supplementation in radiotherapy. Clinical studies on the use of selenium in radiotherapy ...

    Authors: Irma M Puspitasari, Rizky Abdulah, Chiho Yamazaki, Satomi Kameo, Takashi Nakano and Hiroshi Koyama
    Citation: Radiation Oncology 2014 9:125
    Content type: Review Published on:

  6. Intensity-modulated radiotherapy (IMRT) credentialing for a EORTC study was performed using an anthropomorphic head phantom from the Radiological Physics Center (RPC; RPCPH). Institutions were retrospectively req...

    Authors: Damien C Weber, Veronique Vallet, Andrea Molineu, Christos Melidis, Vanda Teglas, Suzanne Naudy, Raphael Moeckli, David S Followill and Coen W Hurkmans
    Citation: Radiation Oncology 2014 9:123
    Content type: Research Published on:

  8. Clinically node negative HNSCC patients have a risk ranging between 18 and 45% of occult metastases, making prophylactic irradiation mandatory. Selective irradiation of nodal target volume based on internation...

    Authors: Jean-François Daisne, Johanne Installé, Benoît Bihin, Marc Laloux, Thierry Vander Borght, Isabelle Mathieu and Georges Lawson
    Citation: Radiation Oncology 2014 9:121
    Content type: Research Published on:

  9. To evaluate the safety and efficacy of Cyberknife stereotactic body radiation therapy (SBRT) and its effect on survival in patients with unresectable huge hepatocellular carcinoma (HCC) unsuitable of other sta...

    Authors: Jenny Y Que, Li-Ching Lin, Kuei-Li Lin, Chia-Hui Lin, Yu-Wei Lin and Ching-Chieh Yang
    Citation: Radiation Oncology 2014 9:120
    Content type: Research Published on:

  10. To evaluate the role of RapidArc (RA) for stereotactic radiosurgery (SRS) of benign brain lesions in comparison to GammaKnife (GK) based technique.

    Authors: Ufuk Abacioglu, Zeynep Ozen, Meltem Yilmaz, Alptekin Arifoglu, Basri Gunhan, Namik Kayalilar, Selcuk Peker, Meric Sengoz, Salih Gurdalli and Luca Cozzi
    Citation: Radiation Oncology 2014 9:119
    Content type: Research Published on:

  11. We prospectively assessed the utility of intensity-modulated radiation therapy (IMRT) with urethral dose reduction and a small margin between the clinical target volume (CTV) and the planning target volume (PT...

    Authors: Shinichi Shimizu, Kentaro Nishioka, Ryusuke Suzuki, Nobuo Shinohara, Satoru Maruyama, Takashige Abe, Rumiko Kinoshita, Norio Katoh, Rikiya Onimaru and Hiroki Shirato
    Citation: Radiation Oncology 2014 9:118
    Content type: Research Published on:

  12. Whole brain radiotherapy (WBRT) plus sequential focal radiation boost is a commonly used therapeutic strategy for patients with brain metastases. However, recent reports on WBRT plus simultaneous in-field boos...

    Authors: Lin Zhou, Jia Liu, Jianxin Xue, Yong Xu, Youling Gong, Lei Deng, Shichao Wang, Renming Zhong, Zhenyu Ding and You Lu
    Citation: Radiation Oncology 2014 9:117
    Content type: Research Published on:

  13. This prospective randomized study aimed to evaluate the role of WBRT + SRS compared to SRS alone and to WBRT alone in improvement of overall survival, brain local control and neurologic manifestations.

    Authors: Mahmoud M El Gantery, HodaM Abd El Baky, Hesham A El Hossieny, Mohamed Mahmoud and Osama Youssef
    Citation: Radiation Oncology 2014 9:116
    Content type: Methodology Published on:

  14. To evaluate clinical outcome after accelerated partial breast irradiation (APBI) in the elderly after high-dose-rate interstitial multi-catheter brachytherapy (HIBT).

    Authors: Caroline Genebes, Marie-Eve Chand, Jocelyn Gal, Mathieu Gautier, Ines Raoust, Tarik Ihrai, Adel Courdi, Jean-Marc Ferrero, Isabelle Peyrottes and Jean-Michel Hannoun-Levi
    Citation: Radiation Oncology 2014 9:115
    Content type: Research Published on:

  15. Metal implants, surgical clips and other foreign bodies may cause ‘streaking’ or ‘star’ artifacts in computed tomography (CT) reconstructions, for example in the vicinity of dental restorations or hip implants...

    Authors: Hendrik Ballhausen, Michael Reiner, Ute Ganswindt, Claus Belka and Matthias Söhn
    Citation: Radiation Oncology 2014 9:114
    Content type: Methodology Published on:

  16. Concurrent chemotherapy and radiation therapy is the preferred standard of care for patients with anal cancer. Several studies have suggested a benefit of intensity-modulated radiation therapy (IMRT) compared ...

    Authors: Stefan Alexander Koerber, Alla Slynko, Matthias F Haefner, David Krug, Clara Schoneweg, Kerstin Kessel, Annette Kopp-Schneider, Klaus Herfarth, Juergen Debus and Florian Sterzing
    Citation: Radiation Oncology 2014 9:113
    Content type: Research Published on:

  17. Stereotactic body radiotherapy (SBRT) is a relatively new treatment for liver tumor. The outcomes of SBRT for liver tumor unfit for ablation and surgical resection were evaluated.

    Authors: Hideomi Yamashita, Hiroshi Onishi, Yasuo Matsumoto, Naoya Murakami, Yukinori Matsuo, Takuma Nomiya and Keiichi Nakagawa
    Citation: Radiation Oncology 2014 9:112
    Content type: Research Published on:

  18. Exposure to radiation provokes cellular responses, which are likely regulated by gene expression networks. MicroRNAs are small non-coding RNAs, which regulate gene expression by promoting mRNA degradation or i...

    Authors: Ling Xie, Jundong Zhou, Shuyu Zhang, Qing Chen, Rensheng Lai, Weiqun Ding, ChuanJun Song, XingJun Meng and Jinchang Wu
    Citation: Radiation Oncology 2014 9:111
    Content type: Research Published on:

  19. To analyze the tumor control, survival outcomes, and toxicity after stereotactic radiosurgery (SRS) for skull base metastases from systemic cancer involving the anterior visual pathway.

    Authors: Giuseppe Minniti, Vincenzo Esposito, Enrico Clarke, Claudia Scaringi, Alessandro Bozzao, Teresa Falco, Vitaliana De Sanctis, Maurizio Maurizi Enrici, Maurizio Valeriani, Mattia Falchetto Osti and Riccardo Maurizi Enrici
    Citation: Radiation Oncology 2014 9:110
    Content type: Study protocol Published on:

  20. To evaluate and compare the risks of secondary cancers from therapeutic doses received by patients with hepatocellular carcinoma (HCC) during intensity-modulated radiotherapy (IMRT), volumetric arc therapy (VM...

    Authors: Dong Wook Kim, Kwangzoo Chung, Weon Kuu Chung, Sun Hyun Bae, Dong Oh Shin, Seongeon Hong, Sung Ho Park, Sung-Yong Park, Chae-Seon Hong, Young Kyung Lim, Dongho Shin, Se Byeong Lee, Hyun-ho Lee, Jiwon Sung and Myonggeun Yoon
    Citation: Radiation Oncology 2014 9:109
    Content type: Research Published on:

  21. We assessed the robustness of passive scattering proton therapy (PSPT) plans for patients in a phase II trial of PSPT for stage III non-small cell lung cancer (NSCLC) by using the worst-case scenario method, a...

    Authors: Zhengfei Zhu, Wei Liu, Michael Gillin, Daniel R Gomez, Ritsuko Komaki, James D Cox, Radhe Mohan and Joe Y Chang
    Citation: Radiation Oncology 2014 9:108
    Content type: Research Published on:

  22. To assess the biochemical recurrence (BCR)-free rate in patients who underwent prostate low-dose-rate brachytherapy (LDR-brachytherapy), using two different definitions (Phoenix definition and PSA ≥ 0.2 ng/mL).

    Authors: Nobumichi Tanaka, Isao Asakawa, Emiko Katayama, Akihide Hirayama, Masatoshi Hasegawa, Noboru Konishi and Kiyohide Fujimoto
    Citation: Radiation Oncology 2014 9:107
    Content type: Research Published on:

  23. To evaluate the volumetric and geometric differences in the ITVs generated by four-dimensional (4D) computed tomography (CT), a modified slow CT scan, and a combination of these CT methods in lung cancer patie...

    Authors: Seong Soon Jang, Gil Ja Huh, Suk Young Park, Po Song Yang, Hae Nam Chung, Jae Hyuk Seo, Ji Chan Park, Young Jun Yang and Eun Youn Cho
    Citation: Radiation Oncology 2014 9:106
    Content type: Research Published on:

  24. In the present study factors affecting survival and toxicity in cerebral metastasized patients treated with stereotactic radiosurgery (SRS) were analyzed with special focus on radiation necrosis.

    Authors: Lars Hendrik Schüttrumpf, Maximilian Niyazi, Silke Birgit Nachbichler, Farkhad Manapov, Nathalie Jansen, Axel Siefert and Claus Belka
    Citation: Radiation Oncology 2014 9:105
    Content type: Research Published on:

  25. The purpose of this study is to evaluate the possible predictors of thyroid disorders after neck radiotherapy, with a focus on radiation dose-volume factors.

    Authors: Zuleyha Akgun, Beste M Atasoy, Zeynep Ozen, Dilek Yavuz, Bahadir Gulluoglu, Meric Sengoz and Ufuk Abacioglu
    Citation: Radiation Oncology 2014 9:104
    Content type: Research Published on:

  26. Radiation fibrosis is not easily measurable although clinical scores have been developed for this purpose. Biomarkers present an alternative more objective approach to quantification, and estimation in blood p...

    Authors: Charlotte B Westbury, Joanne Haviland, Sue Davies, Lone Gothard, Bahja Ahmed Abdi, Mark Sydenham, Jo Bowen, Richard Stratton, Susan C Short and John R Yarnold
    Citation: Radiation Oncology 2014 9:103
    Content type: Research Published on:

  27. To evaluate efficacy and toxicity after salvage brachytherapy (BT) in prostate local recurrence after radiation therapy.

    Authors: Iván Henríquez, Gemma Sancho, Asunción Hervás, Benjamin Guix, Joan Pera, Cristina Gutierrez, Oscar Abuchaibe, Rafael Martínez-Monge, Alejandro Tormo and Alfredo Polo
    Citation: Radiation Oncology 2014 9:102
    Content type: Research Published on:

  28. We attempted to analyze the effects of an increase in the Child-Pugh (CP) score on the overall survival of patients with unresectable hepatocellular carcinoma (HCC) after radiotherapy (RT).

    Authors: Seok Hyun Son, Hong Seok Jang, In-Young Jo, Byung Ock Choi, Jeong Won Jang, Seung Kew Yoon and Chul Seung Kay
    Citation: Radiation Oncology 2014 9:101
    Content type: Research Published on:

  29. Chordomas are relatively rare lesions of the bones. About 30% occur in the sacrococcygeal region. Surgical resection is still the standard treatment. Due to the size, proximity to neurovascular structures and ...

    Authors: Matthias Uhl, Lutz Edler, Alexandra D Jensen, Gregor Habl, Jan Oelmann, Falk Röder, Oliver Jäckel, Jürgen Debus and Klaus Herfarth
    Citation: Radiation Oncology 2014 9:100
    Content type: Study protocol Published on:

  30. To assess the safety and usefulness of neutron brachytherapy (NBT) as an adjuvant in the treatment of patients with gastroesophageal junction adenocarcinoma (GEJAC) with external beam radiation (EBRT), with or...

    Authors: Qifeng Wang, Tao Li, Huiming Liu, Xitang Jia, Bo Liu, Xin Wan and Jinyi Lang
    Citation: Radiation Oncology 2014 9:99
    Content type: Research Published on:

  31. Lymphocyte infiltration is a common feature of radiation-induced pneumonitis and fibrosis, but their contribution to the pathogenic processes is still unclear. Here, we addressed the impact of thorax irradiati...

    Authors: Florian Wirsdörfer, Federica Cappuccini, Muska Niazman, Simone de Leve, Astrid M Westendorf, Lutz Lüdemann, Martin Stuschke and Verena Jendrossek
    Citation: Radiation Oncology 2014 9:98
    Content type: Research Published on:

  32. The objective of this study is to evaluate toxicity and cosmetic outcome in breast cancer patients treated with adjuvant hypo fractionated radiotherapy to the whole breast, and to identify the risk factors for...

    Authors: Patrizia Ciammella, Ala Podgornii, Maria Galeandro, Renato Micera, Dafne Ramundo, Tamara Palmieri, Elisabetta Cagni and Cinzia Iotti
    Citation: Radiation Oncology 2014 9:97
    Content type: Research Published on:

  33. Radiation therapy is one of the recommended treatment options for localized prostate cancer. In randomized trials, dose escalation was correlated with better biochemical control but also with higher rectal tox...

    Authors: Matthias Uhl, Klaus Herfarth, Michael J Eble, Michael Pinkawa, Baukelien van Triest, Robin Kalisvaart, Damien C Weber, Raymond Miralbell, Danny Y Song and Theodore L DeWeese
    Citation: Radiation Oncology 2014 9:96
    Content type: Research Published on:

  34. Long-term survival is rare in patients with glioblastoma (GBM). We set out to determine prognostic factors for patients with favorable and poor prognosis in regard of tumor localization to the subventricular z...

    Authors: Sebastian Adeberg, Tilman Bostel, Laila König, Thomas Welzel, Juergen Debus and Stephanie E Combs
    Citation: Radiation Oncology 2014 9:95
    Content type: Research Published on:

  35. High cure rates for Hodgkin’s lymphoma must be balanced with long-term treatment-related toxicity. Here we report an intensity-modulated radiation therapy (IMRT) technique that achieves adequate target coverag...

    Authors: Khinh Ranh Voong, Kelli McSpadden, Chelsea C Pinnix, Ferial Shihadeh, Valerie Reed, Mohammad R Salehpour, Isidora Arzu, He Wang, David Hodgson, John Garcia, Michalis Aristophanous and Bouthaina S Dabaja
    Citation: Radiation Oncology 2014 9:94
    Content type: Research Published on:

  37. Osteoradionecrosis (ORN) is a critical complication after carbon ion (C-ion) or photon radiotherapy (RT) for head and neck tumors. However, the risk factors for ORN after C-ion RT remain unclear. Therefore, th...

    Authors: Go Sasahara, Masashi Koto, Hiroaki Ikawa, Azusa Hasegawa, Ryo Takagi, Yoshitaka Okamoto and Tadashi Kamada
    Citation: Radiation Oncology 2014 9:92
    Content type: Research Published on:

  39. Data in the literature suggest the existence of oligometastatic disease, a state in which metastases are limited in number and site. Different kinds of local therapies have been used for the treatment of limit...

    Authors: Pierina Navarria, Anna Maria Ascolese, Stefano Tomatis, Luca Cozzi, Fiorenza De Rose, Pietro Mancosu, Filippo Alongi, Elena Clerici, Francesca Lobefalo, Angelo Tozzi, Giacomo Reggiori, Antonella Fogliata and Marta Scorsetti
    Citation: Radiation Oncology 2014 9:91
    Content type: Research Published on:

  40. Anaplastic thyroid cancer (ATC) is an aggressive malignant tumour with a poor prognosis. The median overall survival is described in the literature to be just 6 months, however, in series of selected patients ...

    Authors: Anne-Katrin Dumke, Tanja Pelz and Dirk Vordermark
    Citation: Radiation Oncology 2014 9:90
    Content type: Research Published on:

  41. Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. Despite a multimodal therapy consisting of resection followed by fractionated radiotherapy (RT) combined with the chemotherapeuti...

    Authors: Yvonne Rubner, Carolin Muth, Annedore Strnad, Anja Derer, Renate Sieber, Rolf Buslei, Benjamin Frey, Rainer Fietkau and Udo S Gaipl
    Citation: Radiation Oncology 2014 9:89
    Content type: Research Published on:

  42. Radiotherapy for the treatment of cancer is undergoing an evolution, shifting to the use of heavier ion species. For a plethora of malignancies, current radiotherapy using photons or protons yields marginal be...

    Authors: Cody D Schlaff, Andra Krauze, Arnaud Belard, John J O’Connell and Kevin A Camphausen
    Citation: Radiation Oncology 2014 9:88
    Content type: Review Published on:

  45. Radiotherapy, administered in fractionated as well as ablative settings, is an essential treatment component for breast cancer. Besides the direct tumor cell death inducing effects, there is growing evidence t...

    Authors: Roman Hennel, Nikko Brix, Karin Seidl, Anne Ernst, Heike Scheithauer, Claus Belka and Kirsten Lauber
    Citation: Radiation Oncology 2014 9:85
    Content type: Research Published on:

  46. Cervical cancer is the third most common type of cancer in women worldwide and radiotherapy remains its predominant therapeutic treatment. Artesunate (ART), a derivative of artemisinin, has shown radiosensitiz...

    Authors: Judong Luo, Wei Zhu, Yiting Tang, Han Cao, Yuanyuan Zhou, Rong Ji, Xifa Zhou, Zhongkai Lu, Hongying Yang, Shuyu Zhang and Jianping Cao
    Citation: Radiation Oncology 2014 9:84
    Content type: Research Published on:

  47. To evaluate toxicity and outcome of intensity modulated radiotherapy (IMRT) with simultaneous integrated boost (SIB) to the positive lymph nodes in patients with loco-regional advanced cervical cancer (LRACC).

    Authors: Nikola Cihoric, Coya Tapia, Kamilla Krüger, Daniel M Aebersold, Bernd Klaeser and Kristina Lössl
    Citation: Radiation Oncology 2014 9:83
    Content type: Research Published on:

  48. This clinical study compared four different cases of extensive scalp malignancies treated by intensity-modulated radiation therapy. The merits of coplanar and non-coplanar Step-and-shoot total scalp irradiatio...

    Authors: Christian Ostheimer, Martin Janich, Patrick Hübsch, Reinhard Gerlach and Dirk Vordermark
    Citation: Radiation Oncology 2014 9:82
    Content type: Research Published on:

  50. A discontinuous dose response relationship is a major characteristic of the anti-inflammatory effects of low-dose X-irradiation therapy. Although recent data indicate an involvement of a variety of molecular m...

    Authors: Martin Large, Sebastian Reichert, Stephanie Hehlgans, Claudia Fournier, Claus Rödel and Franz Rödel
    Citation: Radiation Oncology 2014 9:80
    Content type: Research Published on:
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