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  1. Content type: Research

    The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes. The purpose of this st...

    Authors: Hans Paul van der Laan, Wil V Dolsma, John H Maduro, Erik W Korevaar and Johannes A Langendijk

    Citation: Radiation Oncology 2008 3:6

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  2. Content type: Research

    The aim of this treatment planning study was to investigate the potential advantages of intensity-modulated (IM) proton therapy (IMPT) compared with IM photon therapy (IMRT) in nasopharyngeal carcinoma (NPC).

    Authors: Zahra Taheri-Kadkhoda, Thomas Björk-Eriksson, Simeon Nill, Jan J Wilkens, Uwe Oelfke, Karl-Axel Johansson, Peter E Huber and Marc W Münter

    Citation: Radiation Oncology 2008 3:4

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  3. Content type: Research

    To evaluate the risk of rectal, bladder and small bowel toxicity in intensity modulated radiation therapy (IMRT) of the prostate only compared to additional irradiation of the pelvic lymphatic region.

    Authors: Matthias Guckenberger, Kurt Baier, Anne Richter, Dirk Vordermark and Michael Flentje

    Citation: Radiation Oncology 2008 3:3

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  4. Content type: Research

    Androgen suppression treatment (AST) might increase the risk of cardiac morbidity in prostate cancer patients. Possible explanations were provided, however, they disregard the potential contribution of prophyl...

    Authors: Carsten Nieder, Adam Pawinski, Nicolaus H Andratschke and Michael Molls

    Citation: Radiation Oncology 2008 3:2

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  5. Content type: Research

    To compare two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the setting of hypofractionated high-risk prostate cancer treatment.

    Authors: Jasper Yuen, George Rodrigues, Kristina Trenka, Terry Coad, Slav Yartsev, David D'Souza, Michael Lock and Glenn Bauman

    Citation: Radiation Oncology 2008 3:1

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  6. Content type: Research

    Radiation dermatitis is a common side effect of radiation therapy (RT). In severe cases, RT must be interrupted until the skin heals, which can compromise treatment. The purpose of the study was to compare an ...

    Authors: Thomas E Merchant, Christina Bosley, Julie Smith, Pam Baratti, David Pritchard, Tina Davis, Chenghong Li and Xiaoping Xiong

    Citation: Radiation Oncology 2007 2:45

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  7. Content type: Short report

    Set-up errors are an inherent part of radiation treatment process. Coverage of target volume is a direct function of set-up margins, which should be optimized to prevent inadvertent irradiation of adjacent nor...

    Authors: Tejpal Gupta, Supriya Chopra, Avinash Kadam, Jai Prakash Agarwal, P Reena Devi, Sarbani Ghosh-Laskar and Ketayun Ardeshir Dinshaw

    Citation: Radiation Oncology 2007 2:44

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  8. Content type: Research

    It is difficult to determine the most effective approach to patient education or tailor education interventions for patients in radiotherapy without tools that assess patients' specific radiation therapy infor...

    Authors: Georgia KB Halkett and Linda J Kristjanson

    Citation: Radiation Oncology 2007 2:43

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  9. Content type: Research

    The study summarised in this report aimed to investigate the interplay between fluence complexity, dose calculation algorithms, dose calculation spatial resolution and delivery characteristics (monitor units, ...

    Authors: Nicolini Giorgia, Fogliata Antonella, Vanetti Eugenio, Clivio Alessandro, Ammazzalorso Filippo and Cozzi Luca

    Citation: Radiation Oncology 2007 2:42

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  10. Content type: Research

    To compare the dosimetric advantage of three different intensity-modulated radiation therapy (IMRT) plans to a three dimensional (3D) conventional radiation treatment for anal cancer with regards to organs-at-...

    Authors: Cathy Menkarios, David Azria, Benoit Laliberté, Carmen Llacer Moscardo, Sophie Gourgou, Claire Lemanski, Jean-Bernard Dubois, Norbert Aillères and Pascal Fenoglietto

    Citation: Radiation Oncology 2007 2:41

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  11. Content type: Research

    The standard treatment of the axilla in breast cancer used to be an axillary lymph node dissection. An axillary lymph node dissection is known to give substantial risks of morbidity. In recent years the sentin...

    Authors: Patty H Spruit, Sabine Siesling, Marloes AG Elferink, Ernest JA Vonk and Carel JM Hoekstra

    Citation: Radiation Oncology 2007 2:40

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  12. Content type: Research

    Recent developments in radiotherapeutic technology have resulted in a new approach to treating patients with localized lung cancer. We report preliminary clinical outcomes using stereotactic radiosurgery with ...

    Authors: Brian T Collins, Kelly Erickson, Cristina A Reichner, Sean P Collins, Gregory J Gagnon, Sonja Dieterich, Don A McRae, Ying Zhang, Shadi Yousefi, Elliot Levy, Thomas Chang, Carlos Jamis-Dow, Filip Banovac and Eric D Anderson

    Citation: Radiation Oncology 2007 2:39

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  13. Content type: Research

    High-dose radiotherapy is standard treatment for patients with brain cancer. However, in preclinical research external beam radiotherapy is limited to heterotopic murine models– high-dose radiotherapy to the m...

    Authors: Joost JC Verhoeff, Lukas JA Stalpers, Annet W Coumou, Kees Koedooder, Cristina Lavini, Cornelis JF Van Noorden, Jaap Haveman, William P Vandertop and Wouter R van Furth

    Citation: Radiation Oncology 2007 2:38

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  14. Content type: Research

    Accelerated partial breast irradiation is commonly done with the MammoSite applicator, which requires symmetry to treat the patient. This paper describes three cases that were asymmetric when initially placed ...

    Authors: Subhakar Mutyala, Walter Choi, Atif J Khan, Ravi Yaparpalvi, Alexandra J Stewart and Phillip M Devlin

    Citation: Radiation Oncology 2007 2:37

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  15. Content type: Research

    To assess the feasibility and early toxicity of selective, IMRT-based dose escalation (simultaneous integrated boost) to biopsy proven dominant intra-prostatic lesions visible on MRI.

    Authors: Anurag K Singh, Peter Guion, Nancy Sears-Crouse, Karen Ullman, Sharon Smith, Paul S Albert, Gabor Fichtinger, Peter L Choyke, Sheng Xu, Jochen Kruecker, Bradford J Wood, Axel Krieger and Holly Ning

    Citation: Radiation Oncology 2007 2:36

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  16. Content type: Research

    To compare non coplanar field (NCF) with coplanar field (CF) -intensity-modulated radiotherapy (IMRT) planning for ethmoid cancer.

    Authors: Antoine Serre, Katia Idri, Pascal Fenoglietto, Norbert Ailleres, Lore Santoro, Claire Lemanski, Renaud Garrel, Marc Makeieff, Ali Allaw, Jean-Bernard Dubois and David Azria

    Citation: Radiation Oncology 2007 2:35

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  17. Content type: Research

    To evaluate the effects of direct machine parameter optimization in the treatment planning of intensity-modulated radiation therapy (IMRT) for hypopharyngeal cancer as compared to subsequent leaf sequencing in...

    Authors: Barbara Dobler, Fabian Pohl, Ludwig Bogner and Oliver Koelbl

    Citation: Radiation Oncology 2007 2:33

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  18. Content type: Research

    Respiration-gated radiotherapy (RGRT) can decrease treatment toxicity by allowing for smaller treatment volumes for mobile tumors. RGRT is commonly performed using external surrogates of tumor motion. We descr...

    Authors: John R van Sörnsen de Koste, Johan P Cuijpers, Frank GM de Geest, Frank J Lagerwaard, Ben J Slotman and Suresh Senan

    Citation: Radiation Oncology 2007 2:32

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  19. Content type: Research

    Oncological results of radiotherapy for locally advanced prostate cancer (PC) are significantly improved by simultaneous application of LHRH analoga (e.g. goserelin). As 85% of PC express LHRH receptors, we in...

    Authors: Robert M Hermann, Dag Schwarten, Stefanie Fister, Carsten Grundker, Margret Rave-Frank, Mirko Nitsche, Andrea Hille, Paul Thelen, Heinz Schmidberger and Hans Christiansen

    Citation: Radiation Oncology 2007 2:31

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  20. Content type: Research

    Smoking is an important risk factor for the development of cancer. Smoking during radiochemotherapy therapy may have a negative influence on prognosis. We evaluated the effect of smoking during radiochemothera...

    Authors: Sabine Kathrin Mai, Grit Welzel, Verena Haegele and Frederik Wenz

    Citation: Radiation Oncology 2007 2:30

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  21. Content type: Research

    To assess acute (primary endpoint) and late toxicity, quality of life (QOL), biochemical or clinical failure (secondary endpoints) of a hypofractionated IMRT schedule for prostate cancer (PC).

    Authors: Sara Junius, Karin Haustermans, Barbara Bussels, Raymond Oyen, Bianca Vanstraelen, Tom Depuydt, Jan Verstraete, Steven Joniau and Hendrik Van Poppel

    Citation: Radiation Oncology 2007 2:29

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  22. Content type: Research

    To investigate whether Radiation therapy (RT) should follow breast conserving surgery in women with ductal carcinoma in situ from breast cancer (DCIS) with objective of decreased mortality, invasive or non inv...

    Authors: Gustavo A Viani, Eduardo J Stefano, Sérgio L Afonso, Lígia I De Fendi, Francisco V Soares, Paola G Leon and Flavio S Guimarães

    Citation: Radiation Oncology 2007 2:28

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  23. Content type: Short report

    Results of high-dose chemo-radiotherapy (CRT), using the treatment schedules of EORTC study 08972/22973 or radiotherapy (RT) alone were analyzed among all patients (pts) with Non Small Cell Lung Cancer (NSCLC)...

    Authors: Apollonia LJ Uitterhoeve, Mia GJ Koolen, Rob M van Os, Kees Koedooder, Marlou van de Kar, Bradley R Pieters and Caro CE Koning

    Citation: Radiation Oncology 2007 2:27

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  24. Content type: Research

    Intensity-modulated radiation therapy (IMRT) affords unparalleled capacity to deliver conformal radiation doses to tumors in the central nervous system. However, to date, there are few reported outcomes from u...

    Authors: Clifton D Fuller, Mehee Choi, Britta Forthuber, Samuel J Wang, Nancy Rajagiriyil, Bill J Salter and Martin Fuss

    Citation: Radiation Oncology 2007 2:26

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  25. Content type: Research

    The ATM protein is activated as a result of ionizing radiation, and genetic variants of the ATM gene may therefore affect the level of radiation-induced damage. Individuals heterozygous for ATM mutations have bee...

    Authors: Hege Edvardsen, Toril Tefre, Laila Jansen, Phuong Vu, Bruce G Haffty, Sophie D Fosså, Vessela N Kristensen and Anne-Lise Børresen-Dale

    Citation: Radiation Oncology 2007 2:25

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  26. Content type: Research

    At Gesellschaft für Schwerionenforschung (GSI) more than 330 patients have been treated with scanned carbon ion beams in a pilot project. To date, only stationary tumors have been treated. In the presence of m...

    Authors: Christoph Bert and Eike Rietzel

    Citation: Radiation Oncology 2007 2:24

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  27. Content type: Review

    Several experimental strategies of radiation-induced central nervous system toxicity prevention have recently resulted in encouraging data. The present review summarizes the background for this research and th...

    Authors: Carsten Nieder, Nicolaus Andratschke and Sabrina T Astner

    Citation: Radiation Oncology 2007 2:23

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  28. Content type: Research

    Impact of non-pharmacological innovations on cancer cure rates is difficult to assess. It remains unclear, whether outcome improves with 2- [18-F]-fluoro-2-deoxyglucose-positron emission tomography and integra...

    Authors: Sacha Rothschild, Gabriela Studer, Burkhardt Seifert, Pia Huguenin, Christoph Glanzmann, J Bernard Davis, Urs M Lütolf, Thomas F Hany and I Frank Ciernik

    Citation: Radiation Oncology 2007 2:22

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  29. Content type: Research

    To determine the usefulness of dose volume histogram (DVH) factors for predicting the occurrence of radiation pneumonitis (RP) after application of stereotactic radiation therapy (SRT) for lung tumors, DVH fac...

    Authors: Hideomi Yamashita, Keiichi Nakagawa, Naoki Nakamura, Hiroki Koyanagi, Masao Tago, Hiroshi Igaki, Kenshiro Shiraishi, Nakashi Sasano and Kuni Ohtomo

    Citation: Radiation Oncology 2007 2:21

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  30. Content type: Research

    Fibrosis is a common side effect after treatment with ionizing radiation. Several methods to ameliorate debilitating fibrosis have been employed but without consistent results. The goal of this pilot study is ...

    Authors: Nicole L Simone, Benjamin P Soule, Lynn Gerber, Elizabeth Augustine, Sharon Smith, Rosemary M Altemus, James B Mitchell and Kevin A Camphausen

    Citation: Radiation Oncology 2007 2:19

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  31. Content type: Research

    To correlate the metabolic changes with size changes for tumor response by concomitant PET-CT evaluation of lung cancers after radiotherapy.

    Authors: Ching-yee O Wong, Joseph Schmidt, Jeffery S Bong, Suyra Chundru, Larry Kestin, Di Yan, Inga Grills, Marianne Gaskill, Vincent Cheng, Alvaro A Martinez and Darlene Fink-Bennett

    Citation: Radiation Oncology 2007 2:18

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  32. Content type: Research

    Treatment guidelines recommend that curative radiation treatment of prostate cancer be offered only to men whose life expectancy is greater than 10 years. The average life expectancy of North American males is...

    Authors: Paul A Blood and Tom Pickles

    Citation: Radiation Oncology 2007 2:17

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  33. Content type: Research

    Except for early T1,2 N0 stages, the prognosis for patients with oral cavity cancer (OCC) is reported to be worse than for carcinoma in other sites of the head and neck (HNC). The aim of this work was to asses...

    Authors: Gabriela Studer, Roger A Zwahlen, Klaus W Graetz, Bernard J Davis and Christoph Glanzmann

    Citation: Radiation Oncology 2007 2:16

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  34. Content type: Short report

    Carcinoma of the prostate gland is the most frequent malignant tumour affecting male population. While the large majority of tumours is represented by adenocarcinoma, pure squamous cell carcinoma comprises onl...

    Authors: Fernando Munoz, Pierfrancesco Franco, Patrizia Ciammella, Mario Clerico, Mauro Giudici, Andrea Riccardo Filippi and Umberto Ricardi

    Citation: Radiation Oncology 2007 2:15

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  35. Content type: Research

    Hodgkin's lymphoma (HL) survivors who undergo radiotherapy experience increased risks of second cancers (SC) and cardiac sequelae. To reduce such risks, extended-field radiotherapy (RT) for HL has largely been...

    Authors: Eng-Siew Koh, Tu Huan Tran, Mostafa Heydarian, Rainer K Sachs, Richard W Tsang, David J Brenner, Melania Pintilie, Tony Xu, June Chung, Narinder Paul and David C Hodgson

    Citation: Radiation Oncology 2007 2:13

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  36. Content type: Research

    A multi-centre study to assess the value of combined surgical resection and radiotherapy for the treatment of desmoid tumours.

    Authors: Brigitta G Baumert, Martin O Spahr, Arthur Von Hochstetter, Sylvie Beauvois, Christine Landmann, Katrin Fridrich, Salvador Villà, Michael J Kirschner, Guy Storme, Peter Thum, Hans K Streuli, Norbert Lombriser, Robert Maurer, Gerhard Ries, Ernst-Arnold Bleher, Alfred Willi…

    Citation: Radiation Oncology 2007 2:12

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  37. Content type: Research

    Intraoperative Radiotherapy (IORT) is a method by which a critical radiation dose is delivered to the tumour bed immediately after surgical excision. It is being investigated whether a single high dose of radi...

    Authors: Kris S Armoogum, John M Parry, Salam K Souliman, David G Sutton and Colin D Mackay

    Citation: Radiation Oncology 2007 2:11

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  38. Content type: Research

    To evaluate the pathologic response of cervical carcinoma to external beam radiotherapy (EBRT) and high dose rate brachytherapy (HDRB) and outcome.

    Authors: Alexandre A Jacinto, Marcus S Castilho, Paulo ERS Novaes, Pablo R Novick, Gustavo A Viani, João V Salvajoli, Robson Ferrigno, Antonio Cássio A Pellizzon, Stella SS Lima, Maria AC Maia and Ricardo C Fogaroli

    Citation: Radiation Oncology 2007 2:9

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  39. Content type: Research

    To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted to radical prostatectomy (RP) who have achieved complete PSA response and who have never been treated with hormo...

    Authors: Alexandre A Jacinto, Angelo BS Fede, Lívia A Fagundes, João V Salvajoli, Marcus S Castilho, Gustavo A Viani, Ricardo C Fogaroli, Paulo ERS Novaes, Antonio Cássio A Pellizzon, Maria AC Maia and Robson Ferrigno

    Citation: Radiation Oncology 2007 2:8

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  40. Content type: Methodology

    To evaluate the performance of seven different TPS (Treatment Planning Systems: Corvus, Eclipse, Hyperion, KonRad, Oncentra Masterplan, Pinnacle and PrecisePLAN) when intensity modulated (IMRT) plans are desig...

    Authors: Antonella Fogliata, Giorgia Nicolini, Markus Alber, Mats Åsell, Alessandro Clivio, Barbara Dobler, Malin Larsson, Frank Lohr, Friedlieb Lorenz, Jan Muzik, Martin Polednik, Eugenio Vanetti, Dirk Wolff, Rolf Wyttenbach and Luca Cozzi

    Citation: Radiation Oncology 2007 2:7

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  41. Content type: Short report

    To report the toxicity after intensity modulated radiotherapy (IMRT) for patients with localized prostate cancer, as a sole treatment or after radical prostatectomy.

    Authors: Michael J Chen, Eduardo Weltman, Rodrigo M Hanriot, Fábio P Luz, Paulo J Cecílio, José C da Cruz, Frederico R Moreira, Adriana S Santos, Lidiane C Martins and Wladmir Nadalin

    Citation: Radiation Oncology 2007 2:6

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  42. Content type: Review

    Platelet-derived growth factor (PDGF) was originally identified as a constituent of blood serum and subsequently purified from human platelets. PDGF ligand is a dimeric molecule consisting of two disulfide-bon...

    Authors: Minglun Li, Verena Jendrossek and Claus Belka

    Citation: Radiation Oncology 2007 2:5

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  43. Content type: Short report

    Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans or...

    Authors: Robin Cornelissen, Suresh Senan, Imogeen E Antonisse, Hauw Liem, Youke KY Tan, Arjan Rudolphus and Joachim GJV Aerts

    Citation: Radiation Oncology 2007 2:2

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