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  1. Content type: Research

    Hodgkin's lymphoma (HL) survivors who undergo radiotherapy experience increased risks of second cancers (SC) and cardiac sequelae. To reduce such risks, extended-field radiotherapy (RT) for HL has largely been...

    Authors: Eng-Siew Koh, Tu Huan Tran, Mostafa Heydarian, Rainer K Sachs, Richard W Tsang, David J Brenner, Melania Pintilie, Tony Xu, June Chung, Narinder Paul and David C Hodgson

    Citation: Radiation Oncology 2007 2:13

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  2. Content type: Research

    A multi-centre study to assess the value of combined surgical resection and radiotherapy for the treatment of desmoid tumours.

    Authors: Brigitta G Baumert, Martin O Spahr, Arthur Von Hochstetter, Sylvie Beauvois, Christine Landmann, Katrin Fridrich, Salvador Villà, Michael J Kirschner, Guy Storme, Peter Thum, Hans K Streuli, Norbert Lombriser, Robert Maurer, Gerhard Ries, Ernst-Arnold Bleher, Alfred Willi…

    Citation: Radiation Oncology 2007 2:12

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  3. Content type: Research

    Intraoperative Radiotherapy (IORT) is a method by which a critical radiation dose is delivered to the tumour bed immediately after surgical excision. It is being investigated whether a single high dose of radi...

    Authors: Kris S Armoogum, John M Parry, Salam K Souliman, David G Sutton and Colin D Mackay

    Citation: Radiation Oncology 2007 2:11

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  4. Content type: Research

    To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted to radical prostatectomy (RP) who have achieved complete PSA response and who have never been treated with hormo...

    Authors: Alexandre A Jacinto, Angelo BS Fede, Lívia A Fagundes, João V Salvajoli, Marcus S Castilho, Gustavo A Viani, Ricardo C Fogaroli, Paulo ERS Novaes, Antonio Cássio A Pellizzon, Maria AC Maia and Robson Ferrigno

    Citation: Radiation Oncology 2007 2:8

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  5. Content type: Research

    To evaluate the pathologic response of cervical carcinoma to external beam radiotherapy (EBRT) and high dose rate brachytherapy (HDRB) and outcome.

    Authors: Alexandre A Jacinto, Marcus S Castilho, Paulo ERS Novaes, Pablo R Novick, Gustavo A Viani, João V Salvajoli, Robson Ferrigno, Antonio Cássio A Pellizzon, Stella SS Lima, Maria AC Maia and Ricardo C Fogaroli

    Citation: Radiation Oncology 2007 2:9

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  6. Content type: Methodology

    To evaluate the performance of seven different TPS (Treatment Planning Systems: Corvus, Eclipse, Hyperion, KonRad, Oncentra Masterplan, Pinnacle and PrecisePLAN) when intensity modulated (IMRT) plans are desig...

    Authors: Antonella Fogliata, Giorgia Nicolini, Markus Alber, Mats Åsell, Alessandro Clivio, Barbara Dobler, Malin Larsson, Frank Lohr, Friedlieb Lorenz, Jan Muzik, Martin Polednik, Eugenio Vanetti, Dirk Wolff, Rolf Wyttenbach and Luca Cozzi

    Citation: Radiation Oncology 2007 2:7

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  7. Content type: Short report

    To report the toxicity after intensity modulated radiotherapy (IMRT) for patients with localized prostate cancer, as a sole treatment or after radical prostatectomy.

    Authors: Michael J Chen, Eduardo Weltman, Rodrigo M Hanriot, Fábio P Luz, Paulo J Cecílio, José C da Cruz, Frederico R Moreira, Adriana S Santos, Lidiane C Martins and Wladmir Nadalin

    Citation: Radiation Oncology 2007 2:6

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  8. Content type: Review

    Platelet-derived growth factor (PDGF) was originally identified as a constituent of blood serum and subsequently purified from human platelets. PDGF ligand is a dimeric molecule consisting of two disulfide-bon...

    Authors: Minglun Li, Verena Jendrossek and Claus Belka

    Citation: Radiation Oncology 2007 2:5

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  9. Content type: Research

    The sensitizing effects of 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide (DCQ) and ionizing radiation (IR) were determined in four colon cancer cells and in FHs74Int normal intestinal cells.

    Authors: Wafica Itani, Fady Geara, Joelle Haykal, Makhluf Haddadin and Hala Gali-Muhtasib

    Citation: Radiation Oncology 2007 2:1

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  10. Content type: Short report

    Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans or...

    Authors: Robin Cornelissen, Suresh Senan, Imogeen E Antonisse, Hauw Liem, Youke KY Tan, Arjan Rudolphus and Joachim GJV Aerts

    Citation: Radiation Oncology 2007 2:2

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  11. Content type: Research

    Medulloblastoma and other types of tumors that gain access to the cerebrospinal fluid can spread throughout the craniospinal axis. The purpose of this study was to devise a simple multi-compartment kinetic mod...

    Authors: Jeffrey J Meyer, Lawrence B Marks, Edward C Halperin and John P Kirkpatrick

    Citation: Radiation Oncology 2006 1:48

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  12. Content type: Methodology

    Tumors of the skull base pose unique challenges to radiosurgical treatment because of their irregular shapes, proximity to critical structures and variable tumor volumes. In this study, we investigate whether ...

    Authors: Sean P Collins, Nicholas D Coppa, Ying Zhang, Brian T Collins, Donald A McRae and Walter C Jean

    Citation: Radiation Oncology 2006 1:46

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  13. Content type: Research

    The aim of this study was to compare and to validate different dose calculation algorithms for the use in radiation therapy of small lung lesions and to optimize the treatment planning using accurate dose calc...

    Authors: Barbara Dobler, Cornelia Walter, Antje Knopf, Daniella Fabri, Rainer Loeschel, Martin Polednik, Frank Schneider, Frederik Wenz and Frank Lohr

    Citation: Radiation Oncology 2006 1:45

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  14. Content type: Methodology

    Pelvic Radiotherapy (RT) as a postoperative treatment for endometrial cancer improves local regional control. Brachytherapy also improves vaginal control. Both treatments imply significant side effects that a ...

    Authors: Marcus S Castilho, Alexandre A Jacinto, Gustavo A Viani, Andre Campana, Juliana Carvalho, Robson Ferrigno, Paulo ERS Novaes, Ricardo C Fogaroli and Joao V Salvajoli

    Citation: Radiation Oncology 2006 1:44

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  15. Content type: Research

    Hypofractionated radiotherapy may overcome repopulation in rapidly proliferating tumors such as lung cancer. It is more convenient for the patients and reduces health care costs. This study reports our results...

    Authors: Sergio L Faria, Luis Souhami, Lorraine Portelance, Marie Duclos, Te Vuong, David Small and Carolyn R Freeman

    Citation: Radiation Oncology 2006 1:42

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  16. Content type: Research

    4-dimensional CT (4DCT) scans are increasingly used to account for mobility during radiotherapy planning. As variations in respiratory patterns can alter observed motion, with consequent changes in the generat...

    Authors: Ylanga G van der Geld, Frank J Lagerwaard, John R van Sörnsen de Koste, Johan P Cuijpers, Ben J Slotman and Suresh Senan

    Citation: Radiation Oncology 2006 1:43

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  17. Content type: Short report

    We retrospectively evaluated acute toxicity in 88 patients that were treated with capecitabine and concurrent radiotherapy to the upper abdomen. These patients included 28 (32%) with pancreatic adenocarcinoma,...

    Authors: Prajnan Das, Robert A Wolff, James L Abbruzzese, Gauri R Varadhachary, Douglas B Evans, Jean Nicolas Vauthey, Andrew Baschnagel, Marc E Delclos, Sunil Krishnan, Nora A Janjan and Christopher H Crane

    Citation: Radiation Oncology 2006 1:41

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  18. Content type: Research

    Aim of this work was to assess loco-regional disease control in head and neck cancer (HNC) patients treated with postoperative intensity modulated radiation therapy (pIMRT). For comparative purposes, risk feat...

    Authors: Gabriela Studer, Katrin Furrer, Bernard J Davis, Sandro S Stoeckli, Roger A Zwahlen, Urs M Luetolf and Christoph Glanzmann

    Citation: Radiation Oncology 2006 1:40

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  19. Content type: Methodology

    New concepts in radiation oncology are based on the concept that combinations of irradiation and molecular targeted drugs can yield synergistic or at least additive effects. Up to now the combination of two tr...

    Authors: Maximilian Niyazi and Claus Belka

    Citation: Radiation Oncology 2006 1:39

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  20. Content type: Research

    To report the treatment results and prognostic factors of childhood patients with Hodgkin's disease treated with chemotherapy (CT) followed by low dose radiotherapy (RT).

    Authors: Gustavo A Viani, Marcus S Castilho, Paulo E Novaes, Celia G Antonelli, Robson Ferrigno, Cassio A Pellizzon, Ricardo C Fogaroli, Maria A Conte and Joao V Salvajoli

    Citation: Radiation Oncology 2006 1:38

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  21. Content type: Research

    A protocol of electronic portal imaging (EPI) registration for the verification of radiation treatment fields has been implemented at our institution. A template is generated using the reference images, which ...

    Authors: Eric Berthelet, Pauline T Truong, Sergei Zavgorodni, Veronika Moravan, Mitchell C Liu, Jim Runkel, Bill Bendorffe and Dorothy Sayers

    Citation: Radiation Oncology 2006 1:37

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  22. Content type: Research

    Treatment of choroidal melanoma with radiation often involves placement of customized brachytherapy eye-plaques. However, the dosimetric properties inherent in source-based radiotherapy preclude facile dose op...

    Authors: Carlos Esquivel Jr., Clifton D Fuller, Robert G Waggener, Adrian Wong, Martin Meltz, Melissa Blough, Tony Y Eng and Charles R Thomas Jr.

    Citation: Radiation Oncology 2006 1:36

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  23. Content type: Research

    The dose distribution to the rectum, delineated as solid organ, rectal wall and rectal surface, in 3D conformal (3D-CRT) and intensity-modulated radiotherapy treatment (IMRT) planning for localized prostate ca...

    Authors: Matthias Guckenberger, Jürgen Meyer, Kurt Baier, Dirk Vordermark and Michael Flentje

    Citation: Radiation Oncology 2006 1:34

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  24. Content type: Short report

    Mantle Cell Lymphoma (MCL) is a well-known histological and clinical subtype of B-cell non-Hodgkin's Lymphomas. It is usually characterized by an aggressive disease course, presenting with advanced stage disea...

    Authors: Andrea Riccardo Filippi, Pierfrancesco Franco, Marco Galliano and Umberto Ricardi

    Citation: Radiation Oncology 2006 1:35

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  25. Content type: Research

    As a foundation for a dose escalation trial, we sought to characterize duodenal and non-duodenal small bowel organ motion between fractions of pancreatic radiation therapy.

    Authors: Anurag K Singh, Ryan M Tierney, Daniel A Low, Parag J Parikh, Robert J Myerson, Joseph O Deasy, Catherine S Wu, Gisele C Pereira, Sasha H Wahab, Sasa MS Mutics, Perry W Grigsby and Andrew J Hope

    Citation: Radiation Oncology 2006 1:33

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  26. Content type: Short report

    Modern radiotherapy (RT) reduces the side effects at organ at risk. However, skin toxicity is still a major problem in many entities, especially head and neck cancer. Some substances like chemotherapy provide ...

    Authors: Kurt Putnik, Peter Stadler, Christof Schäfer and Oliver Koelbl

    Citation: Radiation Oncology 2006 1:32

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  27. Content type: Methodology

    Intensity modulated radiotherapy (IMRT) is a powerful tool, which might go a long way in reducing radiation doses to critical structures and thereby reduce long term morbidities.

    Authors: Tejinder Kataria, Sheh Rawat, SN Sinha, C Garg, NK Bhalla and PS Negi

    Citation: Radiation Oncology 2006 1:31

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  28. Content type: Research

    We prospectively reviewed response rates, local control, and side effects after non-fractionated stereotactic high single-dose body radiation therapy for lung tumors.

    Authors: Peter Fritz, Hans-Jörg Kraus, Werner Mühlnickel, Udo Hammer, Wolfram Dölken, Walburga Engel-Riedel, Assad Chemaissani and Erich Stoelben

    Citation: Radiation Oncology 2006 1:30

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  29. Content type: Research

    To investigate the outcome of HIV-seropositive patients under highly active antiretroviral treatment (HAART) with anal cancer treated with radiotherapy (RT) alone or in combination with standard chemotherapy (...

    Authors: Christoph Oehler-Jänne, Burkhardt Seifert, Urs M Lütolf and I Frank Ciernik

    Citation: Radiation Oncology 2006 1:29

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  30. Content type: Research

    To report early observation of transient PSA elevations on this pilot study of external beam radiation therapy and magnetic resonance imaging (MRI) guided high dose rate (HDR) brachytherapy boost.

    Authors: Anurag K Singh, Peter Guion, Robert C Susil, Deborah E Citrin, Holly Ning, Robert W Miller, Karen Ullman, Sharon Smith, Nancy Sears Crouse, Denise J Godette, Bronwyn R Stall, CNorman Coleman, Kevin Camphausen and Cynthia Ménard

    Citation: Radiation Oncology 2006 1:28

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  31. Content type: Research

    Salvage therapy in head and neck cancer (HNC) is a controversy issue and the literature is scarce regarding the use of interstitial high-dose rate brachytherapy (I-HDR) in HNC. We evaluated the long-term resul...

    Authors: Antonio CassioAssis Pellizzon, João Victor Salvajoli, Luiz Paulo Kowalski and Andre Lopes Carvalho

    Citation: Radiation Oncology 2006 1:27

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  32. Content type: Research

    The tumor response to preoperative radiotherapy of locally advanced rectal cancer varies greatly, warranting the use of experimental models to assay the efficacy of molecular targeting agents in rectal cancer ...

    Authors: Kjersti Flatmark, Ragnhild V Nome, Sigurd Folkvord, Åse Bratland, Heidi Rasmussen, Mali Strand Ellefsen, Øystein Fodstad and Anne Hansen Ree

    Citation: Radiation Oncology 2006 1:25

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  33. Content type: Research

    Helical Tomotherapy (HT) integrates linear accelerator and computerized tomography (CT) technology to deliver IMRT. Targets are localized (i.e. outlined as gross tumor volume [GTV] and planning target volume [...

    Authors: José A Peñagarícano, Yulong Yan, Chengyu Shi, Mark E Linskey and Vaneerat Ratanatharathorn

    Citation: Radiation Oncology 2006 1:26

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  34. Content type: Research

    To report the relapse and survival rates associated to treatment for patients with stage IC, grade 2 or grade 3 and IB grade 3 diseases considered high risk patients group for relapse.

    Authors: Gustavo A Viani, Barbara F Patia, Antonio C Pellizzon, Marcel D De Melo, Paulo E Novaes, Ricardo C Fogaroli, Maria A Conte and Joao V Salvajoli

    Citation: Radiation Oncology 2006 1:24

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  35. Content type: Research

    The aim of the study was to evaluate the clinical outcome of intensity modulated radiotherapy (IMRT) in 46 patients with paranasal sinus tumors with special respect to treatment-related toxicity.

    Authors: Stephanie E Combs, Stephan Konkel, Daniela Schulz-Ertner, Marc W Münter, Jürgen Debus, Peter E Huber and Christoph Thilmann

    Citation: Radiation Oncology 2006 1:23

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  36. Content type: Research

    There is no consensus as to the prognostic model for brachytherapy of tongue carcinoma. This study was designed to evaluate the prognostic factors for local control based on a large population under a unified ...

    Authors: Sayako Oota, Hitoshi Shibuya, Ryo-ichi Yoshimura, Hiroshi Watanabe and Masahiko Miura

    Citation: Radiation Oncology 2006 1:21

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  37. Content type: Research

    To evaluate the prognostic factors associated with overall survival in patients with brain metastasis treated with whole brain radiotherapy (WBRT) and estimate the potential improvement in survival for patient...

    Authors: Elisa Y Saito, Gustavo A Viani, Robson Ferrigno, Ricardo A Nakamura, Paulo E Novaes, Cassio A Pellizzon, Ricardo C Fogaroli, Maria A Conte and Joao V Salvajoli

    Citation: Radiation Oncology 2006 1:20

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  38. Content type: Review

    Patients with brain metastases represent a heterogeneous group where selection of the most appropriate treatment depends on many patient- and disease-related factors. Eventually, a considerable proportion of p...

    Authors: Carsten Nieder, Anca L Grosu, Sabrina Astner, Reinhard Thamm and Michael Molls

    Citation: Radiation Oncology 2006 1:19

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  39. Content type: Research

    To investigate the potential of parotic gland sparing of intensity modulated radiotherapy (3D-c-IMRT) performed with metallic compensators for head and neck cancer in a clinical series by analysis of dose dist...

    Authors: Thomas G Wendt, Nasrin Abbasi-Senger, Henning Salz, Ines Pinquart, Sven Koscielny, Susi-Marie Przetak and Tilo Wiezorek

    Citation: Radiation Oncology 2006 1:18

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  40. Content type: Research

    Presenting the initial clinical results in the treatment of complex shaped adenoid cystic carcinomas (ACC) of the head and neck region by inverse planned stereotactic IMRT.

    Authors: MW Münter, D Schulz-Ertner, H Hof, A Nikoghosyan, A Jensen, S Nill, P Huber and J Debus

    Citation: Radiation Oncology 2006 1:17

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  41. Content type: Research

    The purpose of the study was the clinical implementation of a kV cone beam CT (CBCT) for setup correction in radiotherapy.

    Authors: Christoph Thilmann, Simeon Nill, Thomas Tücking, Angelika Höss, Bernd Hesse, Lars Dietrich, Rolf Bendl, Bernhard Rhein, Peter Häring, Christian Thieke, Uwe Oelfke, Juergen Debus and Peter Huber

    Citation: Radiation Oncology 2006 1:16

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  42. Content type: Review

    Cervical cancer continues to be a significant health burden worldwide. Globally, the majority of cancers are locally advanced at diagnosis; hence, radiation remains the most frequently used therapeutical modal...

    Authors: Myrna Candelaria, Alicia Garcia-Arias, Lucely Cetina and Alfonso Dueñas-Gonzalez

    Citation: Radiation Oncology 2006 1:15

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  43. Content type: Review

    The risk of severe cardiovascular toxicity, specifically thromboembolic events (TE), in patients with cervical cancer receiving concurrent irradiation and cisplatin chemotherapy is reported to be less than 1% ...

    Authors: Jon C Anders, Perry W Grigsby and Anurag K Singh

    Citation: Radiation Oncology 2006 1:14

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  44. Content type: Research

    To evaluate intensity-modulated radiation therapy (IMRT) as an alternative to conformal radiotherapy (CRT) or 4-field box boost (4FB) in women with gynecologic malignancies who are unsuitable for brachytherapy...

    Authors: Philip Chan, Inhwan Yeo, Gregory Perkins, Anthony Fyles and Michael Milosevic

    Citation: Radiation Oncology 2006 1:13

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