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  1. Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selecti...

    Authors: Huifang He, Jiyuan Li, Ping Jiang, Suqing Tian, Hao Wang, Ruitai Fan, Junqi Liu, Yuyan Yang, Zhibo Liu and Junjie Wang
    Citation: Radiation Oncology 2021 16:216
  2. To evaluate the efficacy of concurrent chemoradiotherapy (CCRT) in subgroups of stage III nasopharyngeal carcinoma (NPC) in the context of intensity-modulated radiotherapy (IMRT).

    Authors: Lei Wang, Zheng Wu, Wanqin Cheng, Dehuan Xie, Feifei Lin, Liangping Xia and Yong Su
    Citation: Radiation Oncology 2021 16:215
  3. To implement a tangential treatment technique for whole breast irradiation using the Varian Halcyon and to compare it with Elekta Synergy Agility plans.

    Authors: Anne Richter, Sonja Wegener, Kathrin Breuer, Gary Razinskas, Stefan Weick, Florian Exner, Klaus Bratengeier, Michael Flentje, Otto Sauer and Bülent Polat
    Citation: Radiation Oncology 2021 16:213
  4. Androgen deprivation therapy (ADT) used for prostate cancer (PCa) management is associated with metabolic and anthropometric toxicity. Metformin given concurrent to ADT is hypothesized to counteract these chan...

    Authors: Julian O. Kim, Megan O. McDonald, Aldrich Ong, Rashmi Koul, Arbind Dubey, William Hunter, Shahida Ahmed, Harvey Quon, Don Yee, Matthew Parliament, Gokulan Sivananthan, Brita Danielson, Lindsay Rowe, Sunita Ghosh and Nawaid Usmani
    Citation: Radiation Oncology 2021 16:212
  5. Radiotherapy may work synergistically with immunotherapy and targeted agents. We aimed to assess the safety and outcomes of stereotactic body radiotherapy (SBRT) plus non-first-line programmed death-1 (PD-1) i...

    Authors: Yang Liu, Zhiling Zhang, Ruiqi Liu, Wensu Wei, Zitong Zhang, Lixin Mai, Shengjie Guo, Hui Han, Fangjian Zhou, Liru He and Pei Dong
    Citation: Radiation Oncology 2021 16:211
  6. Radiotherapy (RT) might lead to atherosclerotic plaque buildup and coronary artery stenosis of breast cancer (BC) survivors, and coronary artery calcium (CAC) might be a sign of preclinical atherosclerosis. Th...

    Authors: Yu-Hsuan Lai, Helen H. W. Chen and Yi-Shan Tsai
    Citation: Radiation Oncology 2021 16:210
  7. In-vivo dosimetry (IVD) is a patient specific measure of quality control and safety during radiotherapy. With regard to current reporting thresholds for significant occurrences in radiotherapy defined by Germa...

    Authors: Sebastian Höfel, Matteo Gandalini, Michael K. Fix, Malte Drescher and Felix Zwicker
    Citation: Radiation Oncology 2021 16:209
  8. Through recent advances in cancer care, the number of long-term survivors has continuously increased. As a result, repetitive use of local radiotherapy for curative or palliative indications might have increas...

    Authors: Sebastian M. Christ, Maiwand Ahmadsei, Lotte Wilke, Anja Kühnis, Matea Pavic, Stephanie Tanadini-Lang and Matthias Guckenberger
    Citation: Radiation Oncology 2021 16:208
  9. There is still no definitely therapeutic evidence of a beneficial effect of chemotherapy with radiotherapy for older patients with esophageal squamous cell carcinoma (ESCC). We aim to determine the influence o...

    Authors: Haishan Wu, Yilin Yu, Qunhao Zheng, Tianxiu Liu, Yahua Wu, Zhiping Wang, Hongying Zheng, Lingyun Liu and Jiancheng Li
    Citation: Radiation Oncology 2021 16:207
  10. In the existing application of beam-matched multiroom proton therapy system, the model based on the commissioning data from the leading treatment room was used as the shared model. The purpose of this study is...

    Authors: Yu-Hua Huang, Chunfeng Fang, Tao Yang, Lin Cao, Gaolong Zhang, Baolin Qu, Yihang Zhang, Zishen Wang and Shouping Xu
    Citation: Radiation Oncology 2021 16:206
  11. Evaluation of delivered dose to the dominant intraprostatic lesion (DIL) for moderately hypofractionated radiotherapy of prostate cancer by cone beam computed tomography (CBCT)-based dose accumulation and targ...

    Authors: Jörg Tamihardja, Sinan Cirsi, Patrick Kessler, Gary Razinskas, Florian Exner, Anne Richter, Bülent Polat and Michael Flentje
    Citation: Radiation Oncology 2021 16:205
  12. The COVID-19 pandemic has stripped many medical students worldwide of their right to quality education. In response, we developed hybrid courses involving aspects of both online and in-person teaching for radi...

    Authors: Tae Hyung Kim, Jin Sung Kim, Hong In Yoon, Joongyo Lee, Jason Joon Bock Lee, Hwa Kyung Byun, Yeona Cho, Yong Bae Kim, Ik Jae Lee, Kyung Hwan Kim and Jee Suk Chang
    Citation: Radiation Oncology 2021 16:204
  13. To study the performance of a proposed deep learning-based autocontouring system in delineating organs at risk (OARs) in breast radiotherapy with a group of experts.

    Authors: Hwa Kyung Byun, Jee Suk Chang, Min Seo Choi, Jaehee Chun, Jinhong Jung, Chiyoung Jeong, Jin Sung Kim, Yongjin Chang, Seung Yeun Chung, Seungryul Lee and Yong Bae Kim
    Citation: Radiation Oncology 2021 16:203
  14. To develop high-quality synthetic CT (sCT) generation method from low-dose cone-beam CT (CBCT) images by using attention-guided generative adversarial networks (AGGAN) and apply these images to dose calculatio...

    Authors: Liugang Gao, Kai Xie, Xiaojin Wu, Zhengda Lu, Chunying Li, Jiawei Sun, Tao Lin, Jianfeng Sui and Xinye Ni
    Citation: Radiation Oncology 2021 16:202
  15. To develop a nomogram model for predicting local progress-free survival (LPFS) in esophageal squamous cell carcinoma (ESCC) patients treated with concurrent chemo-radiotherapy (CCRT).

    Authors: He-San Luo, Ying-Ying Chen, Wei-Zhen Huang, Sheng-Xi Wu, Shao-Fu Huang, Hong-Yao Xu, Ren-Liang Xue, Ze-Sen Du, Xu-Yuan Li, Lian-Xin Lin and He-Cheng Huang
    Citation: Radiation Oncology 2021 16:201
  16. Hypoxia is known to be prevalent in solid tumors such as non-small cell lung cancer (NSCLC) and reportedly correlates with poor prognostic clinical outcome. PET imaging can provide in-vivo hypoxia measurements...

    Authors: Andreas Köthe, Nicola Bizzocchi, Sairos Safai, Antony John Lomax, Damien Charles Weber and Giovanni Fattori
    Citation: Radiation Oncology 2021 16:199
  17. Second head and neck neuroendocrine carcinoma (NEC) after radical radiotherapy for nasopharyngeal carcinoma (NPC) treatment is rarely reported. The prognosis of second cancer is poor, and our research focuses ...

    Authors: Ying-peng Peng, Qiao-dan Liu, Yu-jing Lin, Shun-li Peng, Rong Wang, Xi-wei Xu, Wei Wei, Gui-hua Zhong, Yu-ling Zhou, Ya-qin Zhang, Ye Liu, Si-yang Wang, Hai-yu Hong and Zhi-gang Liu
    Citation: Radiation Oncology 2021 16:198
  18. Approximately one third of cancer patients will develop spinal metastases, that can be associated with back pain, neurological symptoms and deterioration in performance status. Stereotactic radiosurgery (SRS) ...

    Authors: Niccolò Giaj-Levra, Vanessa Figlia, Francesco Cuccia, Rosario Mazzola, Luca Nicosia, Francesco Ricchetti, Michele Rigo, Giorgio Attinà, Claudio Vitale, Gianluisa Sicignano, Antonio De Simone, Stefania Naccarato, Ruggero Ruggieri and Filippo Alongi
    Citation: Radiation Oncology 2021 16:197
  19. Adjuvant therapy is a promising treatment to improve the prognosis of cancer patients, however, the evidence base driving recommendations for adjuvant radiotherapy (ART) or chemotherapy (ACT) in retroperitonea...

    Authors: Xiangji Li, Tong Wu, Mengmeng Xiao, Shanshan Wu, Li Min and Chenghua Luo
    Citation: Radiation Oncology 2021 16:196
  20. Whether adjuvant chemotherapy (AC) after concurrent chemoradiotherapy (CCRT) could provide benefit to esophageal squamous cell carcinoma (ESCC) patients is controversial. Therefore, we decided to investigate t...

    Authors: Ao Liu, Yalin Wang, Xin Wang, Liqiong Zhu, Yu Nie and Minghuan Li
    Citation: Radiation Oncology 2021 16:195
  21. Systemic response to local anticancer treatment is a phenomenon called ‘abscopal effect’. The immune system is thought to play a pivotal role in its occurrence. To date, several cases have been reported, parti...

    Authors: Oliver Vilinovszki, Nicolaus Andratschke, Martin Huellner, Alessandra Curioni-Fontecedro and Stephanie G. C. Kroeze
    Citation: Radiation Oncology 2021 16:194
  22. Stereotactic body radiotherapy (SBRT) is increasingly used for treatment of liver tumors but the effect on metabolic liver function in surrounding tissue is largely unknown. Using 2-deoxy-2-[18F]fluoro-d-galactos...

    Authors: Michael Sørensen, Mette Marie Fode, Jørgen Baltzer Petersen, Marianne Ingerslev Holt and Morten Høyer
    Citation: Radiation Oncology 2021 16:192
  23. To determine the most appropriate radiologic criteria of metastatic retropharyngeal lymph nodes (RLNs) in patients with maxillary sinus cancer (MSC).

    Authors: Yasuo Kosugi, Michimasa Suzuki, Mitsuhisa Fujimaki, Shinichi Ohba, Fumihiko Matsumoto, Yoichi Muramoto, Terufumi Kawamoto, Masaki Oshima, Naoto Shikama and Keisuke Sasai
    Citation: Radiation Oncology 2021 16:190
  24. MR-guided online adaptive stereotactic body radiation therapy (SBRT) for prostate cancer aims to reduce toxicity by full compensation of interfractional uncertainties. However, the process of online adaptation...

    Authors: J. Schaule, M. Chamberlain, L. Wilke, M. Baumgartl, J. Krayenbühl, M. Zamburlini, M. Mayinger, N. Andratschke, S. Tanadini-Lang and M. Guckenberger
    Citation: Radiation Oncology 2021 16:189
  25. In radiotherapy, respiratory-induced tumor motion is typically measured using a single four-dimensional computed tomography acquisition (4DCT). Irregular breathing leads to inaccurate motion estimates, potenti...

    Authors: Duncan den Boer, Johannes K. Veldman, Geertjan van Tienhoven, Arjan Bel and Zdenko van Kesteren
    Citation: Radiation Oncology 2021 16:188
  26. Pelvic radiotherapy is the key treatment for pelvic malignancies, usually including pelvic primary tumour lesions and lymphatic drainage areas in the pelvic region. Therefore, the intestinal tract in the radia...

    Authors: Lina Wang, Xiaohu Wang, Guangwen Zhang, Yan Ma, Qiuning Zhang, Zheng Li, Juntao Ran, Xiaoming Hou, Yichao Geng, Zheng Yang, Shuangwu Feng, Chengcheng Li and Xueshan Zhao
    Citation: Radiation Oncology 2021 16:187
  27. To develop a risk model based on dosimetric metrics to predict local recurrence in nasopharyngeal carcinoma (NPC) patients treated with intensive modulated radiation therapy (IMRT).

    Authors: Wenjun Liao, Jinlan He, Zijian Liu, Maolang Tian, Jiangping Yang, Jiaqi Han and Jianghong Xiao
    Citation: Radiation Oncology 2021 16:186
  28. To investigate the relationship between radiotherapy (RT) and the risk of cerebrovascular mortality (CVM) in head and neck cancer (HNC) survivors aged ≥ 65 years.

    Authors: Qing-Song He, Zhen-Ping Wang, Zhao-Jun Li, Ping Zhou, Chen-Lu Lian, San-Gang Wu and Si-Fang Chen
    Citation: Radiation Oncology 2021 16:185
  29. The role of postoperative radiotherapy (PORT) in cardiovascular-pulmonary disease mortality in patients with stage IIIA-N2 resected non-small cell lung cancer (NSCLC) remains uncertain. The purpose of this pop...

    Authors: Xia Wang, Jiaqi Song, Jie Long, Zhimin Zeng and Anwen Liu
    Citation: Radiation Oncology 2021 16:184
  30. Hybrid magnetic resonance (MR)-guided linear accelerators represent a new horizon in the field of radiation oncology. By harnessing the favorable combination of on-board MR-imaging with the possibility to dail...

    Authors: Francesco Cuccia, Filippo Alongi, Claus Belka, Luca Boldrini, Juliane Hörner-Rieber, Helen McNair, Michele Rigo, Maartje Schoenmakers, Maximilian Niyazi, Judith Slagter, Claudio Votta and Stefanie Corradini
    Citation: Radiation Oncology 2021 16:183
  31. We aimed to assess the feasibility of a dose painting (DP) procedure, known as simultaneous integrated boost intensity modulated radiation Therapy (SIB-IMRT), for treating prostate cancer with dominant intrapr...

    Authors: Seyed Masoud Rezaeijo, Bijan Hashemi, Bahram Mofid, Mohsen Bakhshandeh, Arash Mahdavi and Mohammad Saber Hashemi
    Citation: Radiation Oncology 2021 16:182
  32. In patients with stage III melanoma, the use of adjuvant radiation therapy (RT) after lymph node dissection (LND) may be currently considered in selected high-risk patients to improve tumor control. Melanomas ...

    Authors: Adam R. Wolfe, Priyanka Chablani, Michael R. Siedow, Eric D. Miller, Steve Walston, Kari L. Kendra, Evan Wuthrick and Terence M. Williams
    Citation: Radiation Oncology 2021 16:181
  33. To report preliminary data on treatment outcome and compliance to dose-intensified organ sparing SBRT for prostate cancer using a novel electromagnetic transmitter-based tracking system (RayPilot® System) to a...

    Authors: Raffaella Lucchini, Denis Panizza, Riccardo Ray Colciago, Veronica Vernier, Martina Camilla Daniotti, Valeria Faccenda and Stefano Arcangeli
    Citation: Radiation Oncology 2021 16:180
  34. The purpose of the study was to assess the uterus motions and bladder volume changes of fractional movements in cervical sites throughout the external beam radiotherapy (EBRT) treatment.

    Authors: Xu Li, Lizhen Wang, Zhen Cui, Yukun Li, Pei Liu, Yungang Wang, Jinhong Zhu, Jianmin Zhu, Yong Yin and Zhenjiang Li
    Citation: Radiation Oncology 2021 16:179

    The Correction to this article has been published in Radiation Oncology 2021 16:200

  35. There is limited evidence concerning radiotherapy for painful lymph node metastases (PLM). We evaluated the effectiveness of radiotherapy for PLM using the International Consensus Endpoint in a subgroup analys...

    Authors: Kohsei Yamaguchi, Tetsuo Saito, Ryo Toya, Etsushi Tomitaka, Tomohiko Matsuyama, Yoshiyuki Fukugawa, Takahiro Watakabe, Hirohito Otsuka and Natsuo Oya
    Citation: Radiation Oncology 2021 16:178
  36. The SWORD trial is the first multicenter, single arm, phase II study assessing the safety and efficacy of a PD-1 inhibitor (Sintilimab), stereotactic body radiotherapy (SBRT) and granulocyte–macrophage colony ...

    Authors: Jianjiao Ni, Yue Zhou, Lin Wu, Xinghao Ai, Xiaorong Dong, Qian Chu, Chengbo Han, Xiaofei Wang and Zhengfei Zhu
    Citation: Radiation Oncology 2021 16:177
  37. The aim of this study was to compare the pattern of intra-patient spread of lymph-node (LN)-metastases within the mediastinum as assessed by 18F-FDG PET/CT and systematic endobronchial ultrasound-guided transbron...

    Authors: Maja Guberina, Kaid Darwiche, Hubertus Hautzel, Christoph Pöttgen, Nika Guberina, Thomas Gauler, Till Ploenes, Lale Umutlu, Dirk Theegarten, Clemens Aigner, Wilfried E. E. Eberhardt, Martin Metzenmacher, Marcel Wiesweg, Rüdiger Karpf-Wissel, Martin Schuler, Ken Herrmann…
    Citation: Radiation Oncology 2021 16:176
  38. Contour delineation, a crucial process in radiation oncology, is time-consuming and inaccurate due to inter-observer variation has been a critical issue in this process. An atlas-based automatic segmentation w...

    Authors: Yuka Urago, Hiroyuki Okamoto, Tomoya Kaneda, Naoya Murakami, Tairo Kashihara, Mihiro Takemori, Hiroki Nakayama, Kotaro Iijima, Takahito Chiba, Junichi Kuwahara, Shouichi Katsuta, Satoshi Nakamura, Weishan Chang, Hidetoshi Saitoh and Hiroshi Igaki
    Citation: Radiation Oncology 2021 16:175
  39. Proton beam therapy is a well-established treatment option for patients with uveal melanoma (UM). The treatment procedure, in general, includes placing radiopaque clips to ensure exact eye-positioning during r...

    Authors: Johannes Gollrad, Christopher Rabsahl, Aline-Isabel Riechardt, Jens Heufelder, Andrea Stroux, Ute Goerling, Antonia Joussen, Volker Budach and Dirk Boehmer
    Citation: Radiation Oncology 2021 16:174
  40. This study aimed to investigate the effect of abdominal compression on tumour motion and target volume and to determine suitable planning target volume (PTV) margins for patients treated with lung stereotactic...

    Authors: Yuanjun Qi, Jianbin Li, Yingjie Zhang, Qian Shao, Xijun Liu, Fengxiang Li, Jinzhi Wang, Zhenxiang Li and Wei Wang
    Citation: Radiation Oncology 2021 16:173
  41. To investigate risk factors for developing radiation-associated facial lymphedema (FL) in nasopharyngeal carcinoma (NPC) patients after concurrent chemoradiation (CCRT).

    Authors: Donghyun Kim, Jiho Nam, Wontaek Kim, Dahl Park, Jihyeon Joo, Hosang Jeon and Yongkan Ki
    Citation: Radiation Oncology 2021 16:172
  42. To compare the dosimetric, normal tissue complication probability (NTCP), secondary cancer complication probabilities (SCCP), and excess absolute risk (EAR) differences of volumetric modulated arc therapy (VMA...

    Authors: Yun Zhang, Yuling Huang, Shenggou Ding, Xingxing Yuan, Yuxian Shu, Jinhui Liang, Qingfeng Mao, Chunling Jiang and Jingao Li
    Citation: Radiation Oncology 2021 16:171
  43. Stereotactic Body Radiotherapy (SBRT) has shown effectiveness in treating bone metastases to alleviate pain. The benefit of SBRT may be further harnessed especially when radiating disease from primary malignan...

    Authors: Eric K. Nguyen, Kimmen Quan, Sameer Parpia, Stephan Tran and Anand Swaminath
    Citation: Radiation Oncology 2021 16:170
  44. To evaluate the combined effect of rotational error and dose gradient on target dose coverage in frameless stereotactic radiotherapy.

    Authors: Jai-Woong Yoon, Soah Park, Kwang-Ho Cheong, Sei-Kwon Kang and Tae Jin Han
    Citation: Radiation Oncology 2021 16:169
  45. The objective of this study was to analyze the amplitude of translational and rotational movements occurring during stereotactic body radiotherapy (SBRT) of spinal metastases in two different positioning devic...

    Authors: Ahmed Hadj Henni, David Gensanne, Maximilien Roge, Chantal Hanzen, Guillaume Bulot, Elyse Colard and Sebastien Thureau
    Citation: Radiation Oncology 2021 16:168
  46. To evaluate the influence of target dose heterogeneity on normal tissue dose sparing for peripheral lung tumor stereotactic body radiation therapy (SBRT).

    Authors: Zhigong Wei, Xingchen Peng, Yan Wang, Lianlian Yang, Ling He, Zheran Liu, Jingjing Wang, Xiaoli Mu, Ruidan Li and Jianghong Xiao
    Citation: Radiation Oncology 2021 16:167

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