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Table 5 Predictive factors of the 2-year PFS in multivariate analysis

From: Dynamics in the expression of programmed death ligand 1 and cluster of differentiation 163 in the tumor microenvironment of uterine cervical cancer: a single-center retrospective study

Variables

Multivariate analysis

HR*

95% CI

p-value

PD-1 expression levels

1.18

(0.68, 2.05)

0.56

PD-L1 expression levels

1.03

(1.00, 1.07)

0.04

CD8 expression levels

1.13

(0.97, 1.32)

0.13

CD68 expression levels

1.03

(0.99, 1.06)

0.19

CD163 expression levels

1.06

(1.01, 1.10)

0.02

FoxP3 expression levels

1.24

(0.67, 2.30)

0.49

HIF-1α expression levels

1.00

(0.97, 1.03)

0.89

  1. These data were adjusted for age, EBRT dose at the external os, and HDR-ICBT dose at the external os
  2. PFS progression-free survival, HR hazard ratio, CI confidence interval, PD-L1 programmed death ligand 1, EBRT external-beam radiation therapy, HDR-ICBT high-dose-rate intracavity brachytherapy
  3. *HR was calculated as an increase in one unit of expression level
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Radiation Oncology

ISSN: 1748-717X

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