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Table 2 Baseline characteristics of patients

From: Dynamics in the expression of programmed death ligand 1 and cluster of differentiation 163 in the tumor microenvironment of uterine cervical cancer: a single-center retrospective study

Characteristics

Treatment success

Treatment failure

p-value

Characteristics

Treatment success

Treatment failure

p-value

(n = 12)

(n = 14)

(n = 12)

(n = 14)

Age (year)

EBRT field, n (%)

0.46

 Median (range)

61 (47–89)

49 (33–72)

0.03

 Whole pelvis

11 (92)

14 (100)

 

ECOG Performance Status, n (%)

0.78

 Small pelvis

1 (8)

0 (0)

 

 0

10 (83)

12 (86)

 

Chemotherapy, n (%)

0.58

 1

1 (8)

2 (14)

 

 0 mg/m2

2 (17)

1 (7)

 

 2

1 (8)

0 (0)

 

 ≥ 100 mg/m2

10 (83)

13 (93)

 

Histology, n (%)

1.00

EBRT dose, n (%)

0.20

 Squamous cell carcinoma

12 (100)

13 (93)

 

 1.8 Gy × 28 fr

10 (83)

14 (100)

 

 Adenocarcinoma

0 (0)

1 (7)

 

 1.6 Gy × 31 fr

1 (8)

0 (0)

 

Stage (FIGO 2009), n (%)

0.51

 2.0 Gy × 15 fr

1 (8)

0 (0)

 

 I

1 (8)

3 (21)

 

HDR-ICBT dose at Point A, n (%)

0.59

 II

6 (50)

9 (64)

 

 5 Gy × 2 fr

1 (8)

0 (0)

 

 III

3 (25)

1 (7)

 

 5 Gy × 4 fr

0 (0)

1 (7)

 

 IV

2 (17)

1 (7)

 

 5 Gy × 5 fr

3 (25)

3 (21)

 

Tumor diameter, n (%)

1.00

 5 Gy × 6 fr

8 (67)

6 (43)

 

 < 4 cm

2 (17)

2 (14)

 

 5 Gy × 7 fr

0 (0)

2 (14)

 

 ≥ 4 cm

10 (83)

12 (86)

 

 5 Gy × 8 fr

0 (0)

1 (7)

 

Lymph node metastasis, n (%)

0.23

 5 Gy × 5 fr. + 6 Gy × 1 fr

0 (0)

1 (7)

 

 Negative

7 (58)

4 (29)

 

Treatment effect, n (%)

0.02

 Positive

5 (42)

10 (71)

 

 CR

12 (100)

8 (57)

 

Distant metastasis, n (%)

0.58

 PR

0 (0)

6 (43)

 

 Negative

10 (83)

13 (93)

 

 SD

0 (0)

0 (0)

 

 Positive

2 (17)

1 (7)

 

 PD

0 (0)

0 (0)

 
  1. ECOG Eastern Cooperative Oncology Group, FIGO International Federation of Gynecology and Obstetrics, EBRT external-beam radiation therapy, HDR-ICBT high-dose-rate intracavity brachytherapy, CR complete response, PR partial response, SD stable disease, PD progressive disease