Postoperative radiotherapy for supraglottic cancer on real-world data: can we reduce dose to lymph node levels?

Radiation Oncology

Table 3 Basic characteristics of patients with regional failure

Patient no	Centers	Tumor location	TNM stage	Neck dissection	Dose(Gy)/fraction	Recurrence region	Time to recurrence (months)	Results
1	Center 1	unilateral without midline involvement	T2N2b	Ipsilateral level II-IV neck dissection	50–60/25–30	Contralateral level II (LRR)	34	Complicated with base of tongue cancer, 40 months later
2	Center 2	central	T2N2c	Bilateral level II-IV neck dissection	50/25	Level IV of left neck (LRR)	34	Survival
3	Center 2	unilateral without midline involvement	T3N2b	Bilateral level II-IV neck dissection	50/25	Ipsilateral level III (HRR)	39	Lung metastasis, 56 months later
4	Center 2	central	T3N2b	Bilateral level II-IV neck dissection	50/25	Level II of left neck (HRR)	8	Survival
5	Center 2	unilateral without midline involvement	T4aN3 (ENE)	Bilateral level II-IV neck dissection	50–60/25–30	Ipsilateral level II (HRR)	11	Lost to follow-up

ENE, extra nodal extension; HRL, high-risk levels (involved nodal levels); LRL, low-risk levels (uninvolved nodal levels)

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