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Table 1 Selection of target volumes for supraglottic cancer

From: Postoperative radiotherapy for supraglottic cancer on real-world data: can we reduce dose to lymph node levels?

Center 1

Stage (AJCC/UICC 8th)

CTV1

CTV2

T3-4N0

GTVtb with a margin of 1–1.5 cm and bilateral levels II, III

Bilateral levels IV

N + 

GTVtb with a margin of 1–1.5 cm and involved nodal levels and the next levels

Uninvolved bilateral levels II-IV; Ib or/and V

Dose prescription

60.06 Gy in 33 fractions

50.96 Gy in 28 fractions

Center 2

Stage (AJCC/UICC 8th)

CTV

N0/N + 

GTVtb with a margin of 1–1.5 cm and bilateral levels II-IV

Dose prescription

50 Gy in 25 fractions

ENE or positive margin

 
 

GTVnd-tb, GTVtb

Dose prescription

66–70 Gy

  1. AJCC, American Joint Committee on Cancer; UICC, Union for International Cancer
  2. Control; ENE, extra nodal extension; CTV, nodal clinical target volume