Table 3 Acute treatment toxicities
Toxicity | No. of patients (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
CRT group (n = 70) | RT group (n = 70) | |||||||||
Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | |
Hematological toxicity | ||||||||||
Leukopenia | 2 (2.9) | 11 (15.7) | 46 (65.7) | 9 (12.9) | – | 31 (44.3) | 24 (34.3) | 4 (5.7) | 0 (0.0) | – |
Neutropenia | 7 (10.0) | 28 (40.0) | 18 (25.7) | 9 (12.9) | – | 12 (17.1) | 5 (7.1) | 1 (1.4) | 0 (0.0) | – |
Anemia | 52 (74.3) | 16 (22.9) | 1 (1.4) | 0 (0.0) | 0 (0.0) | 14 (20.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Thrombocytopenia | 40 (57.1) | 18 (25.7) | 4 (5.7) | 0 (0.0) | – | 30 (42.9) | 5 (7.1) | 0 (0.0) | 0 (0.0) | – |
Constitutional symptom | ||||||||||
Fatigue | 43 (61.4) | 11 (15.7) | 2 (2.9) | – | – | 14 (20.0) | 6 (8.6) | 2 (2.9) | – | – |
GI | ||||||||||
Nausea | 26 (37.1) | 21 (30.0) | 5 (7.1) | – | – | 32 (45.7) | 9 (12.9) | 5 (7.1) | – | – |
Vomiting | 16 (22.9) | 6 (8.6) | 1 (1.4) | 0 (0.0) | 0 (0.0) | 6 (8.6) | 5 (7.1) | 1 (1.4) | 0 (0.0) | 0 (0.0) |
Radiation induced | ||||||||||
Dermatitis | 23 (32.9) | 5 (7.1) | 0 (0) | 0 (0) | 0 (0) | 5 (7.1) | 1 (1.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Esophagitis | 49 (70.0) | 11 (15.7) | 1 (1.4) | 0 (0.0) | 0 (0.0) | 39 (55.7) | 5 (7.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Pneumonitis | 36 (51.4) | 17 (24.3) | 2 (2.9) | 0 (0.0) | 2 (2.9) | 27 (38.6) | 13 (18.6) | 1 (1.4) | 0 (0.0) | 0 (0.0) |