Radiotherapy-related details | Clinical experience (years)---Responders N (%) | ||||
---|---|---|---|---|---|
All (n=484) | 1–5 (n=82) | 6–10 (n=121) | 11-20 (n=163) | ≥ 21 (n=118) | |
Total dose | |||||
50 Gy | 382 (78.9) | 56 (68.3) | 98 (81.0) | 133 (81.6) | 95 (80.5) |
54 Gy | 99 (20.5) | 25 (30.5) | 22 (18.2) | 29 (17.8) | 23 (19.5) |
Others | 3 (0.6) | 1 (1.2) | 1 (0.8) | 1 (0.6) | 0 (0.0) |
Targeted region closest to clinical practicea | |||||
Lung stump + ipsilateral hilus + regions containing positive LNs | 283 (58.5) | 42 (51.2) | 62 (51.2) | 99 (60.7) | 80 (67.8) |
Lung stump + ipsilateral mediastinum ± ipsilateral supraclavicular LNsb | 238 (49.3) | 52 (63.4) | 64 (52.9) | 75 (46.3) | 47 (39.8) |
Lung stump + ipsilateral mediastinum ± contralateral upper mediastinum c | 132 (27.3) | 22 (26.8) | 26 (21.5) | 49 (30.1) | 35 (29.7) |
Prophylactic radiotherapy for stumpa | |||||
Surgical margins were near to tumor margins | 375 (77.5) | 56 (68.3) | 89 (73.6) | 131(80.4) | 99 (83.9) |
Central type | 214 (44.2) | 27 (32.9) | 51 (42.1) | 76 (46.6) | 60 (50.8) |
Any condition | 102 (21.1) | 21 (25.6) | 28 (23.1) | 32 (19.6) | 21 (17.8) |
Lung V20 | |||||
<20% | 173 (35.7) | 33 (40.2) | 43 (35.5) | 51 (31.3) | 46 (39.0) |
<25% | 217 (44.8) | 33 (40.2) | 51 (42.1) | 79 (48.5) | 54 (45.8) |
<30% | 87 (18.0) | 16 (19.5) | 24 (19.8) | 32 (19.6) | 15 (12.7) |
Others | 7 (1.4) | 0 (0.0) | 3 (2.5) | 1 (0.6) | 3 (2.5) |
Heart dose constraint a, c | |||||
No limitation | 19 (3.9) | 10 (12.2) | 4 (3.3) | 1 (0.6) | 4 (3.4) |
Yes, Heart V30 | 437 (90.3) | 68 (82.9) | 107 (88.4) | 152 (93.3) | 110 (93.2) |
<30% | 71 (14.7) | 7 (8.5) | 18 (14.9) | 23 (14.1) | 23 (20.9) |
<35% | 45 (9.3) | 6 (7.3) | 5 (4.1) | 17 (11.2) | 17 (15.5) |
<40% | 280 (57.9) | 43 (52.4) | 75 (62.0) | 100 (65.8) | 62 (56.4) |
Other | 41 (8.5) | 12 (14.6) | 9 (7.4) | 12 (7.9) | 8 (7.3) |
Yes, Heart V40 | 244 (50.4) | 30 (36.6) | 60 (49.6) | 89 (54.6) | 65 (55.1) |
<20% | 14 (2.9) | 1 (1.2) | 4 (3.3) | 3 (1.8) | 6 (5.1) |
<25% | 13 (2.7) | 2 (2.4) | 1 (0.8) | 6 (3.7) | 4 (3.4) |
<30% | 207 (42.8) | 26 (31.7) | 53 (43.8) | 76 (46.6) | 52 (44.1) |
Other | 10 (2.1) | 1 (1.2) | 2 (1.7) | 4 (2.5) | 3 (2.5) |