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Table 3 Percentage fulfillment of dose acceptance criteria before and after intra-fractional movement

From: Geometric and dosimetric consequences of intra-fractional movement in single isocenter non-coplanar stereotactic radiosurgery

PTV margin

TC1 (V100%PD > 95%)

TC2 (V95%PD > 99%)

Dmin > 90% (GTV)

TC1 /TC2/Dmin > 90%

V12Gy < 10 cc (Normal brain)

All criteria

Original plan

0 mm

98.2%

98.2%

96.4%

96.4%

98.0%

93.9%

1 mm

98.2%

98.2%

98.2%

98.2%

87.8%

85.7%

2 mm

98.2%

98.2%

98.2%

98.2%

71.4%

69.4%

Simulated plan with intra-fraction movements

0 mm

85.7% (p < 0.001)

78.6% (p < 0.001)

76.8% (p < 0.001)

73.2% (NA)

98.0% (See Table 4)

69.4% (NA)

1 mm

98.2% (p = 0.07)

98.2% (p = 0.66)

98.2% (p < 0.001)

98.2% (NA)

87.8% (See Table 4)

85.7% (NA)

2 mm

98.2% (p = 0.18)

98.2% (p = 0.16)

98.2% (p < 0.001)

98.2% (NA)

71.4% (See Table 4)

69.4% (NA)

  1. The bracketed data show the p-values evaluated for the changes of GTV V100%PD, V95%PD and Dmin before and after intra-fractional movements using the Wilcoxon signed rank tests