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Table 4 Comparisons of the mean values of the dosimetric parameters for RP-risk benefit group

From: CT ventilation image-guided helical Tomotherapy at sparing functional lungs for locally advanced lung cancer: analysis of dose-function metrics and the impact on pulmonary toxicity

Variable

Planning strategy

Anatomical plan

Func_plan Top10

Func_plan Top20

Func_plan Top30

Func_plan Top40

Func_plan Top50

PTV

 V60 (%)

96.47 ± 1.33

96.17 ± 0.47

95.98 ± 0.48

95.98 ± 0.53

95.67 ± 0.57

95.65 ± 0.57

 CI

0.85 ± 0.06

0.86 ± 0.03

0.85 ± 0.06

0.84 ± 0.06

0.76 ± 0.11

0.76 ± 0.11

 HI

0.06 ± 0.01

0.07 ± 0.01

0.07 ± 0.02

0.09 ± 0.02†

0.11 ± 0.04†

0.10 ± 0.03†

Heart

 Dmean(Gy)

14.71 ± 6.16

14.56 ± 6.52

15.21 ± 6.74

15.96 ± 7.87

16.74 ± 8.78

16.99 ± 8.64

Spinal cord

 Dmax(Gy)

32.79 ± 5.50

32.16 ± 6.43

33.87 ± 6.37

37.44 ± 6.49†

40.17 ± 6.89†

40.54 ± 6.90†

Esophagus

 Dmean (Gy)

22.97 ± 6.70

24.08 ± 6.59

23.88 ± 6.98

23.22 ± 7.13

23.70 ± 7.56

23.49 ± 7.55

  1. †p < 0.05 and ††p < 0.01, indicate significantly increased when compared with anatomical plan; Func_plan Top10/20/30/40/50, means top 10%/20%/30%/40%/50% percentile functional volume were defined as the high-functional lung in planning optimization
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Radiation Oncology

ISSN: 1748-717X

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