Table 3 Mean difference in plan quality and OAR dosimetric parameters between treatment techniques
Parameter | Technique | Mean difference (95% CI) | Comparison P value | Global P value |
|---|---|---|---|---|
Conformity index (RTOG) | DCAT vs IMRT | − 0.3 (− 0.4, − 0.1) | 0.0002 | |
DCAT vs VMAT | 0.1 (− 0.04, 0.3) | 0.14 | < .0001 | |
IMRT vs VMAT | 0.4 (0.3, 0.5) | < .0001 | ||
Conformity index (Paddick) | DCAT vs IMRT | 0.098 (0.056, 0.14) | < .0001 | |
DCAT vs VMAT | − 0.027 (− 0.070, 0.016) | 0.21 | < .0001 | |
IMRT vs VMAT | − 0.13 (− 0.17, − 0.083) | < .0001 | ||
Gradient index | DCAT vs IMRT | − 0.4 (− 0.6, − 0.3) | < .0001 | |
DCAT vs VMAT | − 0.4 (− 0.6, − 0.3) | < .0001 | < .0001 | |
IMRT vs VMAT | 0.01 (− 0.2, 0.2) | 0.89 | ||
Brainstem D1cc (Gy) | DCAT vs IMRT | 0.5 (0.1, 1.0) | 0.030 | |
DCAT vs VMAT | 1.1 (0.6 1.5) | < .0001 | < .0001 | |
IMRT vs VMAT | 0.6 (0.1, 1.0) | 0.016 | ||
Cochlea D0.03cc (Gy) | DCAT vs IMRT | − 0.1 (− 0.8, 0.5) | 0.64 | |
DCAT vs VMAT | 2.4 (1.8, 3.0) | < .0001 | < .0001 | |
IMRT vs VMAT | 2.5 (2.0, 3.2) | < .0001 | ||
Cochlea Dmean (Gy) | DCAT vs IMRT | 0.2 (− 0.4, 0.7) | 0.48 | |
DCAT vs VMAT | 2.3 (1.8, 2.9) | < .0001 | < .0001 | |
IMRT vs VMAT | 2.1 (1.6, 2.7) | < .0001 |