Table 3 Dosimetric parameters of ABM and ABM-high for four types of plans
Parameter | OAR doses | Dose differences rate (p value) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
IMRT | IMRT-BMS | IMPT | IMPT-BMS | IMRT versus IMPT | IMRT versus IMRT-BMS | IMPT versus IMPT-BMS | IMRT-BMS versus IMPT-BMS | IMRT-BMS versus IMPT | IMRT versus IMPT-BMS | |
ABM | ||||||||||
V5 | ||||||||||
Median | 100 | 100 | 99.2 | 91.3 | − 0.8% | 0% | − 8.0% | − 8.7% | − 0.8% | − 8.7% |
(min–max) | (94.4–100) | (94.1–100) | (90.9–100) | (85.4–98.9) | < 0.001 | 0.893 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
V10 | ||||||||||
Median | 99.9 | 89.2 | 91.3 | 67.2 | − 8.6% | − 10.7% | − 26.4% | − 24.7% | 2.4% | − 32.7% |
(min–max) | (90.4–100) | (76.7–95.6) | (75.5–95.7) | (56.7–78.3) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.514 | < 0.001 |
V20 | ||||||||||
Median | 91.7 | 67.7 | 68.5 | 39.8 | − 25.3% | − 26.2% | − 41.9% | − 41.2% | 1.2% | − 56.6% |
(min–max) | (75.9–95.6) | (58.6–77.3) | (38.3–80) | (31–50.4) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.922 | < 0.001 |
V30 | ||||||||||
Median | 64.6 | 51.1 | 54.6 | 23.4 | − 15.5% | − 20.9% | − 57.1% | − 54.2% | 6.8% | − 63.8% |
(min–max) | (44–76.5) | (39.3–56.6) | (25.7–89.6) | (16.1–35) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.025 | < 0.001 |
V40 | ||||||||||
Median | 24.9 | 24 | 27.3 | 10.9 | 9.6% | − 3.6% | − 60.1% | − 54.6% | 13.8% | − 56.2% |
(min–max) | (13.1–38.1) | (15.5–35.5) | (10.5–38.9) | (6.4–23.1) | 0.017 | 0.256 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Dmean | ||||||||||
Median | 33.1 | 28.2 | 29.1 | 19.4 | − 12.1% | − 14.8% | − 33.3% | − 31.2% | 3.2% | − 41.4% |
(min–max) | (29–39.7) | (26.4–32.7) | (23.6–35.87) | (17.7–28.5) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.081 | < 0.001 |
ABM-high | ||||||||||
V5 | ||||||||||
Median | 100 | 100 | 99.4 | 89.8 | − 0.6% | 0% | − 9.7% | − 10.2% | − 0.6% | − 10.2% |
(min–max) | (92.9–100) | (92.7–100) | (87.8–100) | (80.5–98) | < 0.001 | 0.249 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
V10 | ||||||||||
Median | 99.9 | 89.7 | 91.7 | 63.1 | − 8.2% | − 10.2% | − 31.2% | − 29.7% | 2.2% | − 36.8% |
(min–max) | (87–100) | (82.4–98.6) | (78–99.2) | (58.7–70.9) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.001 | < 0.001 |
V20 | ||||||||||
Median | 91.8 | 67.7 | 70.2 | 37.8 | − 23.5% | − 26.3% | − 46.2% | − 44.2% | 3.7% | − 58.8% |
(min–max) | (80–97.9) | (36.3–86.4) | (47.1–93.2) | (31.2–45.1) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.118 | < 0.001 |
V30 | ||||||||||
Median | 66.5 | 50.5 | 56 | 21.7 | − 15.8% | − 24.1% | − 61.3% | − 57.0% | 10.9% | − 67.4% |
(min–max) | (50.8–90.9) | (42.9–74.1) | (35.9–89.8) | (18.9–27.9) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.006 | < 0.001 |
V40 | ||||||||||
Median | 30.2 | 26.1 | 32 | 10.6 | 6.0% | − 13.6% | − 66.9% | − 59.4% | 22.6% | − 64.9% |
(min–max) | (17.7–61.1) | (17.9–40) | (16.6–55.3) | (6.6–14.7) | 0.037 | 0.04 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Dmean | ||||||||||
Median | 33.7 | 28.1 | 28.9 | 18.7 | − 14.2% | − 16.6% | − 35.3% | − 33.5% | 2.8% | − 44.5% |
(min–max) | (29–39.7) | (26.4–32.7) | (23.6–35.87) | (17.7–28.5) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.081 | < 0.001 |