Table 3 Prognostic factors of KPS and ADL impairment after reirradiation; univariate analysis

KPS

Male gender

0.88 [0.40; 1.98]

0.763

Initial brain surgery

1.20 [0.48; 3.03]

0.697

Motor deficiency

1.32 [0.45; 3.88]

0.615

Antiepileptic medication

0.71 [0.32; 1.59]

0.405

Headaches

2.44 [1.07; 5.59]

0.035

Age (years) > 60

1.0 [0.45; 2.24]

1

Steroids (mg)

1.47 [0.64; 3.38]

0.363

PTV (cc)*

1.57 [1.19; 2.08]

0.028

KPS (%) ≥ 90

1.51 [0.60; 3.81]

0.388

Time from RTCT to fSBReRT (months) < 12

1.36 [0.59; 3.10]

0.473

Number of recurrences before reirradiation ≥ 1

1.27 [0.50; 3.20]

0.617

Multifocality

1.66 [0.49; 5.62]

0.412

Brain topography

Cortical

1

Subcortical

2.54 [1.00;6.44]

0.050

ADL

Male gender

0.66 [0.24; 1.77]

0.410

Initial brain surgery

0.76 [0.26; 2.21]

0.617

Motor deficiency

2.99 [0.94; 9.54]

0.064

Antiepileptic medication

0.79 [0.29; 2.13]

0.650

Headaches

2.52 [0.91; 6.99]

0.075

Age (years) > 60

0.95 [0.35; 2.57]

0.924

Steroids (mg)

2.12 [0.78; 5.78]

0.141

PTV (cc)*

1.0 [1.0; 1.0]

0.481

KPS (%) ≥ 90

0.26 [0.09; 0.74]

0.011

Time from RTCT to fSBReRT (months) < 12

2.39 [0.77; 7.45]

0.131

Number of recurrences before reirradiation ≥ 1

1.36 [0.43; 4.30]

0.599

Multifocality

1.78 [0.36; 6.98]

0.583

Brain topography

Cortical

1

Subcortical

2.11 [0.68; 6.58]

0.196