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Table 3 Dynamics of the inflammatory serum parameter during and after radiotherapy (RT) (n = 20)

From: Characterization and dynamics of the soluble immunological microenvironment in melanoma patients undergoing radiotherapy

 

pre-RT

mid-RT

post-RT

p (pre vs. mid)

p (pre vs. post)

PD-L1

90.1

92.6

93.3

0.445

0.398

PD-L2

4.4

5.3

6.4

0.263

0.063

IL-6

8.5

8.4

9.5

0.913

0.920

CTLA-4

153.7

102.8

75.3

0.642

0.472

  1. Mean serum levels of the respective parameters before (pre-RT), during (mid-RT) and after completion of RT (post-RT) were assessed. PD-L1, IL-6 and CTLA-4 in pg/ml; PD-L2 in ng/ml. Significance of mean values was tested via one-sample t-tests
  2. CTLA, cytotoxic t-lymphocyte-associated protein; IL, Interleukin; PD-L, programmed death-ligand