From: Neoadjuvant radiotherapy for resectable retroperitoneal sarcoma: a meta-analysis
Trial Name | Status | Primary Aims/Findings | Ref |
---|---|---|---|
Retroperitoneal SArcoma Registry: an International Prospective Initiative (RESAR) (NCT03838718) | Recruiting (12/2030)a | To assess the survival after surgery for primary RPS resection (Sarcoma subtype: primary RPS amenable to surgical resection) | NA |
Proton or Photon RT for Retroperitoneal Sarcoma (NCT01659203) | Recruiting (08/2025)a | To determine the maximum tolerated dose (MTD) of preoperative IG-IMRT with simultaneously integrated boost to the high-risk margin of retroperitoneal sarcoma To determine the local control rate after the protocol treatment (IG-IMPT or IMRT MTD with simultaneously integrated boost to the high-risk margin) followed by surgical resection (Sarcoma subtype: primary RPS) | NA |
Neoadjuvant Irradiation of Retroperitoneal Soft Tissue Sarcoma With Ions Retro-Ion (Retro-Ion) (NCT04219202) | Recruiting (05/2024)a | To evaluate the safety and feasibility of a hypofractionated, accelerated radiation approach based on the incidence of grade 3–5 NCI common terminology criteria for adverse events toxicity and/or termination of the planned therapy for any reason with neoadjuvant radiation with active beam guidance of the retroperitoneal sarcomas using protons or carbon ions before subsequent tumor resection (Sarcoma subtype: RPS which is resectable or marginally resectable) | NA |
Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis (NCT00091351) | Completed (02/2006)b | Compare progression-free survival of patients with primary soft tissue sarcoma of the retroperitoneum or pelvis treated with surgery with vs without preoperative radiotherapy (Sarcoma subtype: primary RPS) | NR |
Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal Sarcoma (NCT05224934) | Recruiting (12/2024)a | To investigate the feasibility and peri-operative complications of preoperative hypo-fractionated radiotherapy followed by surgery for retroperitoneal sarcoma (Sarcoma subtype: primary RPS) | NA |