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Table 4 Operating characteristics of the stopping rule for safety

From: A safety study of intraoperative radiation therapy following stereotactic body radiation therapy and multi-agent chemotherapy in the treatment of localized pancreatic adenocarcinoma: study protocol of a phase I trial

Underlying risk

0.25

0.30

0.35

0.40

% of time study stops

21.6%

32.1%

45%

58.5%

Expected sample size

16.7

15.2

13.4

11.7

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Radiation Oncology

ISSN: 1748-717X

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