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Table 2 Clavien-Dindo classification

From: A safety study of intraoperative radiation therapy following stereotactic body radiation therapy and multi-agent chemotherapy in the treatment of localized pancreatic adenocarcinoma: study protocol of a phase I trial

Grade I

Any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic, and radiological interventions.

Allowed therapeutic regimens are: drugs as antiemetics, antipyretics, analgesics, diuretics, electrolytes, and physiotherapy. This grade also includes wound infections opened at the bedside

Grade II

Requiring pharmacological treatment with drugs other than such allowed for grade I complications

Blood transfusions and total parenteral nutrition are also included

Grade III

Requiring surgical, endoscopic or radiological intervention

IIIa

Intervention not under general anesthesia

IIIb

Intervention under general anesthesia

Grade IV

Life-threatening complication (including CNS complications)* requiring IC/ICU management

IVa

Single organ dysfunction (including dialysis)

IVb

Multi-organ dysfunction

Grade V

Death of a patient

  1. *Brain hemorrhage, ischemic stroke, subarachnoid bleeding, but excluding transient ischemic attacks
  2. CNS Central nervous system, IC Intermediate care, ICU Intensive care unit
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Radiation Oncology

ISSN: 1748-717X

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