Intensity modulated proton therapy for early-stage glottic cancer: high-precision approach to laryngeal function preservation with exceptional treatment tolerability

Table 2 Mean number of CTCAE v4.03 toxicity events and overall toxicity per patient (n = 15)

	Mean	95%-CI	Patients	%
Acute short-term toxicities
CTC grade I	3.3	2.5–4.2	6	40.0
CTC grade II	0.9	0.4–1.3	9	60.0
CTC grade I-II	4.2	3.4–5.0	15	100.0
Late toxicities
CTC grade I	1.7	1.0–2.6	11	73.3
CTC grade II	0.1	0–0.3	2	13.3
CTC grade I-II	1.8	1.2–2.8	13	86.6
Overall toxicities
CTC grade I	4.1	3.1–5.3	5	33.3
CTC grade II	1.0	0.5–1.5	10	66.7
CTC grade I-II	5.1	4.2–6.3	15	100.0

CTCAE Common Terminology Criteria of Adverse Events, CI Confidence interval; Comment: Acute toxicity that continued in the late phase was counted as both acute and late toxicity, but only counted once in the overall toxicity events per patient category. If a patient had more than one toxicity event, only the highest toxicity grade was counted once in the total count category

ISSN: 1748-717X