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Table 1 Patient and treatment characteristics (n = 15 patients)

From: Intensity modulated proton therapy for early-stage glottic cancer: high-precision approach to laryngeal function preservation with exceptional treatment tolerability

 

Patients

%

Sex

Female

1

6.7

Male

14

93.3

T-stage prior to RT

  

T1a

6

40.0

T1b

4

26.7

T2

5

33.3

Smoking

 ≥ 10 pack-years

8

53.3

 < 10 pack-years

1

6.7

Never

6

40.0

RT setting

Additive

2

13.3

Definitive

13

86.7

Gantry beam angle

30°/330°

1

6.7

40°/320°

6

40.0

50°/310°

7

46.6

60°/320°

1

6.7

 

Median

Range

Age prior to RT (years)

68

35–83

KPS prior to RT (%)

90

60–100

BMI prior to RT (kg/m²)

25.9

18.4–30.4

BMI post RT (kg/m²)

24.9

18.1–30.4

Total dose (Gy RBE)

70

66–70

Single dose (Gy RBE)

2.0

1.8–2.3

RT fractions

35

30–35

Treatment time per fraction (min)

6

4–9

PTV (ccm)

63.2

16.0–183.9

CTV (ccm)

22.9

3.4–128.4

GTV (ccm)

1.8

0.4–7.4

Total number of scan spots

4306

1236–11641

Maximum energy protons (MeV/u)

109

91–127

  1. RT Radiotherapy, IMPT Intensity modulated proton therapy, KPS Karnofsky performance score, BMI Body mass index, RBE Relative biological effectiveness, ccm cubic centimeters, PTV Planning target volume, CTV Clinical target volume, GTV Gross tumor volume