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Fig. 5 | Radiation Oncology

Fig. 5

From: Comparing biological effectiveness guided plan optimization strategies for cranial proton therapy: potential and challenges

Fig. 5

Patient 5: Columns display distributions of constant relative biological effectiveness (RBE) weighted dose (D1.1), dose-averaged linear energy transfer (LETd) in voxels above 10 Gy and proton track-ends. Each row shows D1.1, LETd and track-end distributions for one optimization strategy. Primary planning target volume (blue) is shown together with the brainstem (white) and both optic nerves (magenta). DOSEopt: dose-only optimization, TEopt: track-end optimization, LETopt: dose-averaged linear energy transfer (LETd) optimization with dose threshold, DDopt: Dirty dose optimization, DRBEopt: variable RBE-weighted dose optimization

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