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Fig. 2 | Radiation Oncology

Fig. 2

From: Ex vivo γH2AX assay for tumor radiosensitivity in primary prostate cancer patients and correlation with clinical parameters

Fig. 2

Immunofluorescence image of γH2AX foci distribution in PCa patients and corresponding PSMA PET images. Immunofluorescence images from two patients are shown. Patient #14 was classified as radio sensitive, whereas patient #5 as radio resistant. DNA DSB marker γH2AX foci is presented in yellow (Alexa 555), DNA counterstain (in blue) was used to visualize the cell nuclei (Hoechst 33,342) and AMACR in red for PCa visualization. For each patient the PSMA PET scans are shown. The GTVs are marked with blue, respectively. SUV-mean/max values are shown. Abbreviations: PCa: prostate cancer; DNA DSB: double strand breaks; AMACR: AlphaMethylacylCoA Racemase; GTV: gross tumour volume; PSMA PET: positron emission tomography with rostate-specific membrane antigen

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