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Fig. 4 | Radiation Oncology

Fig. 4

From: Ku70 affects the frequency of chromosome translocation in human lymphocytes after radiation and T-cell acute lymphoblastic leukemia

Fig. 4

Effects of Ku70 interference and overexpression on the frequency of chromosome translocations. A Representative western blots images in Ku70 interference (XRCC6-shRNA) and scr-RNA (control) cells. B The protein expression of Ku70 and PARP1 (n = 3) in Ku70 interference (XRCC6-shRNA) and scr-RNA (control) cells. C Analysis of the frequency of chromosome translocations (n = 3) in Ku70 interference (XRCC6-shRNA) and scr-RNA (control) cells. D Representative western blots images in Ku70 overexpression (pcDNA3.1 + Ku70) and pcDNA3.1 (control) cells. E The protein expression of Ku70 and PARP1 (n = 3) in Ku70 overexpression (pcDNA3.1 + Ku70) and pcDNA3.1 (control) cells. F Analysis of the frequency of chromosome translocations (n = 3) in Ku70 overexpression (pcDNA3.1 + Ku70) and pcDNA3.1 (control) cells. *indicates that P < 0.05, **marks that P < 0.01. ***meand that P < 0.001. Sh, short hairpin; Scr, scrambled control

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