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Fig. 2 | Radiation Oncology

Fig. 2

From: Ku70 affects the frequency of chromosome translocation in human lymphocytes after radiation and T-cell acute lymphoblastic leukemia

Fig. 2

Correlation between the frequency of chromosome translocations and the level of Ku70. A Representative images of photomicrographs showed FISH painted human chromosome 1, 4 (green) and 2 (red) in metaphase lymphocytes after X-rays. Chromosomes translocations were displayed with the arrows. B FISH analysis showed that X-ray radiations increased the frequency of chromosome translocations of PBLs. C Pearson correlation analysis of chromosome translocations and Ku70 mRNA showed a significant positive correlation of the frequency of chromosome translocations versus the expression of Ku70 mRNA (Pearson r = 0.4877; P = 0.004). D Pearson correlation analysis of chromosome translocations and Ku70 protein level displayed a significant positive correlation of the frequency of chromosome translocations versus the expression of Ku70 protein (Pearson r = 0.3038; P = 0.0358). *indicates that P < 0.05, and **represents that P < 0.01. ***refers to that P < 0.001

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Radiation Oncology

ISSN: 1748-717X

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