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Fig. 1 | Radiation Oncology

Fig. 1

From: Ku70 affects the frequency of chromosome translocation in human lymphocytes after radiation and T-cell acute lymphoblastic leukemia

Fig. 1

Dose- and time-response of radiation on DSBs and Ku70 in human PBLs. A RT-qPCR analysis of Ku70 mRNA. The expression of Ku70 mRNA accumulated in 1 Gy and 2 Gy X-irradiated PBLs. B, C Representative images and western blot analysis. Ku70 also showed the increment in protein level after 1 Gy and 2 Gy X-ray radiations. D Neutral comet assay. PBLs were isolated and subjected to 0.5 Gy, 1 Gy and 2 Gy X-ray radiations and then subjected to the neutral comet assay after 0 h and 72 h, respectively. E Results of Comet images analyzed. All data are presented as mean value ± SD of three independent experiments. *indicates that P < 0.05, and ***denotes that P < 0.001 compared with the control

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