Table 1 Patients’ and lesions’ characteristics (n = 105)

Age, median (range)

58 (36–85)

Primary tumor

Lung

49 (46.6%)

Breast

23 (22%)

Kidney

11 (10.5%)

Melanoma

10 (9.5%)

Gastrointestinal

5 (4.8%)

Gynecological

5 (4.8%)

Head & neck

1 (0.9%)

Bladder

1 (0.9%)

Concomitant systemic therapy

Chemotherapy

29 (26.2%)

Targeted therapy

28 (25%)

Immunotherapy

15 (13.5%)

Hormone therapy

3 (2.8%)

None

29 (26.2%)

Unknown

7 (6.3%)

Previous WBRT

Yes

15 (14%)

No

90 (86%)

Brainstem site (n = 111)

Midbrain

33 (30%)

Pons

63 (57%)

Medulla oblongata

15 (13%)

Fraction number (n = 111)

1

58 (52.3%)

2

1 (0.9%)

3

38 (34%)

4

2 (1.8%)

5

12 (11%)

Median total dose SRS (Gy) (range)

18 (12–20)

Median total dose HSRT (Gy) (range)

20 (14–32)

Median BED (Gy10) (range)

35.7 (23.8–60)

Median/mean GTV volume SRS (cc) (n = 58)

0.4/1.3 (0.02–2.8)

Median/mean GTV volume HSRT (cc) (n = 53)

0.4/1.5 (0.08–23.6)