Table 4 Univariate and multivariable analysis of FFDM
Variable | All (N = 115) | G2 sarcoma (N = 53) | G3 sarcoma (N = 62) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate analysis | Multivariable analysis | Univariate analysis | Multivariable analysis | Univariate analysis | Multivariable analysis | |||||||
HR (95% CI) | p-Value | HR (95% CI) | p-Value | HR (95% CI) | p-Value | HR (95% CI) | p-Value | HR (95% CI) | p-Value | HR (95% CI) | p-Value | |
Age (in years) | ||||||||||||
< 61 | Ref | Ref | Ref | |||||||||
≥ 61 | 1.137 (.614–2.105) | .683 | .732 (.186–2.883) | .655 | 1.038 (.507–2.125) | .918 | ||||||
Sex | ||||||||||||
Male | Ref | Ref | Ref | |||||||||
Female | .744 (.399–1.387) | .352 | 1.112 (.323–3.823) | .866 | .885 (.406–1.926) | .757 | ||||||
KPS | ||||||||||||
< 90 | Ref | Ref | Ref | Ref | Ref | |||||||
≥ 90 | .476 (.253-.895) | .021* | .569 (.298–1.087) | .088 | 2.361 (.488–11.419) | .285 | .306 (.143-.652) | .002* | .496 (.219–1.135) | .093 | ||
Location | ||||||||||||
Other | Ref | Ref | Ref | |||||||||
Extremity | .818 (.415–1.612) | .561 | 1.893 (.399–8.971) | .421 | .535 (.250–1.143) | .106 | ||||||
Tumor size (in cm) | ||||||||||||
< 8.8 | Ref | Ref | Ref | |||||||||
≥ 8.8 | 1.282 (.686–2.394) | .436 | .766 (.197–2.977) | .700 | 1.284 (.609–2.704) | .511 | ||||||
Resection margin | ||||||||||||
R0 | Ref | Ref | Ref | |||||||||
R1/2 | 1.443 (.510–4.086) | .489 | 2.092 (.417–10.490) | .370 | 1.780 (.415–7.644) | .438 | ||||||
n/a | .624 (.188–2.072) | .441 | - | - | 1.724 (.519–5.727) | .374 | ||||||
Therapy | ||||||||||||
Other therapy | Ref | Ref | Ref | Ref | Ref | |||||||
Neoadjuvant RCT | .344 (.141-.836) | .018* | .415 (.166–1.036) | .059 | .965 (.195–4.767) | .965 | .182 (.061-.540) | .002* | .267 (.083-.862) | .027* | ||
Hyperthermia | ||||||||||||
No | Ref | Ref | Ref | |||||||||
Yes | 1.890 (.857–4.171 | .115 | 2.510 (.514–12.258) | .256 | 1.800 (.714–4.541) | .213 | ||||||